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Fructose

A monosaccharide in sweet fruits and honey that is soluble in water, alcohol, or ether. It is used as a preservative and an intravenous infusion in parenteral feeding.

Also Known As:

Apir Levulosa; Baxter Brand of Fructose; Bieffe Brand of Fructose; Braun Brand of Fructose; Ern Brand of Fructose; Fleboplast Levulosa; Fresenius Kabi Brand of Fructose; Grifols Brand of Fructose; Instituto Farmacologico Brand of Fructose; Levulosa; Levulosa Baxter; Levulosa Braun; Levulosa Grifols; Levulosa Ibys; Levulosa Ife; Levulosa Mein; Levulosado Bieffe Medit; Levulosado Braun; Levulosado Vitulia; Plast Apyr Levulosa Mein; Levulosa, Apir; Levulosa, Fleboplast; Levulose

Networked: 2828 relevant articles (136 outcomes, 441 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Carbohydrates: 4088
- Monosaccharides: 152
  - Hexoses: 107
    - Fructose: 2828
  - Ketoses: 4
    - Fructose: 2828

Experts

1.	Johnson, Richard J: 43 articles (11/2015 - 12/2005)
2.	Havel, Peter J: 26 articles (06/2015 - 02/2002)
3.	Adeli, Khosrow: 26 articles (12/2014 - 01/2002)
4.	Anuradha, C V: 22 articles (05/2010 - 01/2002)
5.	Stanhope, Kimber L: 19 articles (06/2015 - 07/2007)
6.	Nakagawa, Takahiko: 18 articles (09/2015 - 12/2005)
7.	Tappy, Luc: 18 articles (08/2015 - 07/2005)
8.	Lanaspa, Miguel A: 17 articles (09/2015 - 03/2010)
9.	Ishimoto, Takuji: 13 articles (09/2015 - 01/2011)
10.	Sautin, Yuri Y: 13 articles (02/2015 - 10/2007)

Related Diseases

1.	Insulin Resistance 08/01/2014 - "ZSP also markedly improved the HDL-C level, homeostasis model assessment for insulin resistance (HOMA-IR) and β-cell function (HOMA-β), and decreased the atherogenic index (AI) of the mice exposed to high-fructose water. " 08/01/2010 - "The study evaluated the protective effects of Cissus quadrangularis stem extract (CQEt) on oxidant-antioxidant balance and insulin resistance (IR) in rats fed high fat-high fructose diet (HFFD) and also tested its free-radical scavenging property in vitro. " 10/05/2015 - "NFAT inhibitor tributylhexadecylphosphoniumbromide, ameliorates high fructose induced insulin resistance and nephropathy." 06/01/2013 - "Activation of PPARα ameliorates hepatic insulin resistance and steatosis in high fructose-fed mice despite increased endoplasmic reticulum stress." 10/01/2012 - "Amla (Emblica officinalis) extract is effective in preventing high fructose diet-induced insulin resistance and atherogenic dyslipidemic profile in ovariectomized female albino rats."
2.	Hypertriglyceridemia 06/01/2011 - "Globularia alypum aqueous extract decreases hypertriglyceridemia and ameliorates oxidative status of the muscle, kidney, and heart in rats fed a high-fructose diet." 01/01/2015 - "In the present study, a high-fructose diet (HFrD) fed rat model of hypertriglyceridemia was employed to further delineate the underlying mechanism by which NDGA exerts its anti-hypertriglyceridemic action. " 01/01/2013 - "In the study of hypertriglyceridemia induced by fructose, AEBO in doses of 400 mg/kg and 800 mg/kg reduced TG levels by 48.2% and 48.7%, respectively. " 01/01/2011 - "These studies provide novel insight into the mechanisms involved in fructose-mediated hepatic hypertriglyceridemia and identify fructose-uptake as a new potential therapeutic target for lipid-associated diseases." 09/01/2009 - "This study evaluated the effects that different doses of MATK-90 had on lipid levels and clinical parameters in male Wistar rats fed a high-fructose diet used to induce hypertriglyceridemia (TAG > or = 300 mg/dL). "
3.	Hyperinsulinism (Hyperinsulinemia) 02/01/2014 - "Rats were fed 25 % fructose solution for hyperinsulinemia with L.casei Zhang for prevention or therapy. " 11/01/2011 - "Therefore, to further clarify the detailed mechanisms of perivascular nervous system malfunction induced by chronic hyperinsulinemia, we investigated the neurogenic vascular responses and distribution of perivascular nerves using mesenteric vascular beds isolated from fructose-loaded rats with hyperinsulinemia. " 04/01/2011 - "FR dams demonstrated increased total caloric intake and maternal hyperinsulinemia at E21 as well as increased maternal plasma fructose levels at E21 and P10. " 06/01/2008 - "Compared with control diet, fructose feeding induced hyperinsulinemia, HOMA-IR and increased triglyceride (all P<0.01). " 06/30/2007 - "The increase in GIR was lower in fructose-fed groups than in control groups under similar hyperinsulinemia. "
4.	Hypertension (High Blood Pressure) 05/01/2015 - "This study evaluates the effect of hydro-alcoholic celery leaf extract onsystolic blood pressure (SBP), heart rate (HR) and lipid profile in animals' model of hypertension induced by fructose. " 01/01/2014 - "Although most controlled feeding trials have failed to show an adverse effect of fructose on blood pressure, concerns continue to be raised regarding the role of fructose in hypertension. " 01/01/2012 - "Future studies are needed to address whether fructose-stimulated NHE3 activity may contribute to renal injury and hypertension." 11/01/2011 - "This study investigated whether RA supplementation prevents cardiac abnormalities and hypertension in fructose-fed rats (FFR). " 02/01/2011 - "Further studies are warranted in order to understand the role of fructose in the development of hypertension."
5.	Hyperlipidemias (Hyperlipidemia) 01/01/2011 - "The results of present study indicate that Mentha piperita had significant beneficial effects against fructose-induced hyperlipidemia and showed good antioxidant activity. " 12/01/1995 - "In this study we assessed the acute effects of the consumption of varying amounts of fat and fructose on the magnitude of postprandial lipemia. " 01/01/2015 - "The ingestion of a fructose-containing beverage combined with fat cream exacerbates postprandial lipidemia in young healthy women." 01/01/2015 - "Eight apparently healthy men (Mean ± SEM; age = 27 ± 2 years) participated in a crossover study to examine the effects of acute resistance exercise on next-day postprandial lipemia resulting from a high-fructose, high-fat meal. " 01/01/2015 - "Resistance Exercise Attenuates High-Fructose, High-Fat-Induced Postprandial Lipemia."

Related Drugs and Biologics

1.	Glucose (Dextrose)
2.	Insulin (Novolin)
3.	Sucrose (Saccharose)
4.	Lipoproteins (Lipoprotein)
5.	Cholesterol
6.	formycin diphosphate (FDP)
7.	Blood Glucose (Blood Sugar)
8.	Nitric Oxide (Nitrogen Monoxide)
9.	pioglitazone (Actos)
10.	Mannose (D-Mannose)

Related Therapies and Procedures

1.	Boron Neutron Capture Therapy
2.	Oral Administration
3.	Total Parenteral Nutrition
4.	Ovariectomy (Oophorectomy)
5.	Drug Therapy (Chemotherapy)