Fox-Fordyce Disease

Chronic pruritic disease, usually in women, characterized by small follicular papular eruptions in APOCRINE GLANDS areas. It is caused by obstruction and rupture of intraepidermal apocrine ducts.

Also Known As:

Networked: 18 relevant articles (3 outcomes, 0 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1.	Malignant Atrophic Papulosis
2.	Hidradenitis Suppurativa
3.	Hidradenitis
4.	Skin Diseases
5.	Folliculitis (Sycosis)

Experts

1.	Kaya, Zeliha: 1 article (01/2015)
2.	George, Anisha: 1 article (01/2015)
3.	Bhatia, Anuradha: 1 article (01/2015)
4.	Thomas, Emy: 1 article (01/2015)
5.	Kaya Erdoğan, Hilal: 1 article (01/2015)
6.	Bulur, Işıl: 1 article (01/2015)
7.	Paus, Ralf: 1 article (12/2014)
8.	Schneider, Marlon R: 1 article (12/2014)
9.	Bernad, Isabel: 1 article (06/2014)
10.	Irarrazaval, Isabel: 1 article (06/2014)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Fox-Fordyce Disease:

1.	pimecrolimus (Elidel)FDA Link 09/01/2006 - "Pimecrolimus is effective in Fox-Fordyce disease." 05/01/2012 - "Clinical effects of topical pimecrolimus in a patient with Fox-Fordyce disease."
2.	ProgesteroneFDA LinkGeneric 07/01/1956 - "[Remission of Fox-Fordyce disease after gonadotropic hormone serum therapy observed following progesterone injections for disorders of hormonal balance]."
3.	HormonesIBA 07/01/1956 - "[Remission of Fox-Fordyce disease after gonadotropic hormone serum therapy observed following progesterone injections for disorders of hormonal balance]."
4.	Clindamycin (Cleocin)FDA LinkGeneric 01/01/2015 - "Fox-Fordyce disease: a report of 2 cases responding to topical clindamycin." 10/01/1995 - "Fox-Fordyce disease treated with topical clindamycin solution." 01/01/1992 - "Fox-Fordyce disease: successful treatment with topical clindamycin in alcoholic propylene glycol solution."
5.	Propylene Glycol (1,2 Propanediol)FDA LinkGeneric 01/01/1992 - "Fox-Fordyce disease: successful treatment with topical clindamycin in alcoholic propylene glycol solution."
6.	Tacrolimus (Prograf)FDA LinkGeneric 01/01/2015 - "Clinical Effects of Topical Tacrolimus on Fox-Fordyce Disease."
7.	Tretinoin (Retinoic Acid)FDA LinkGeneric 11/01/1979 - "Tretinoin treatment for Fox-Fordyce disease."
8.	Testosterone (Sustanon)FDA Link 05/01/1952 - "Testosterone for apocrine diseases: hidrosadenitis, Fox-Fordyce disease."
9.	Keratins (Keratin)IBA 07/01/2013 - "Laser therapy induces damage to follicular infundibulum, resulting in altered maturation of keratinocytes which led to keratin plugging causing the common pathologic features in Fox-Fordyce disease. "
10.	Dichlorodiphenyldichloroethane (DDD)IBA 06/01/2013 - "Nine case reports have linked Dowling-Degos disease (DDD) to HS and two reports related HS to Fox-Fordyce disease (FF), but because both occur in the axilla this might be a mere coincidence. "

Therapies and Procedures

1.	Injections 07/01/1956 - "[Remission of Fox-Fordyce disease after gonadotropic hormone serum therapy observed following progesterone injections for disorders of hormonal balance]."
2.	Electrocoagulation (Electrocautery) 01/01/1973 - "Fox-Fordyce disease in the post-menopausal period treated successfully with electrocoagulation."
3.	Lasers (Laser) 07/01/2013 - "Differences in the physiologic features of the anatomic sites, in the susceptibility to laser-induced injury among these areas, or additional factors may contribute to Fox-Fordyce disease. " 07/01/2013 - "We report the first case of Fox-Fordyce disease developing in women after completing treatment with a depilatory hair laser appearing in the axillae, umbilicus, and pubis. " 06/01/2014 - "Fox Fordyce disease (FFD) has been recently described as an adverse effect of laser hair removal. " 06/01/2014 - "Fox Fordyce disease as a secondary effect of laser hair removal." 07/01/2013 - "Two recent reports indicated laser hair removal as a novel cause of axillary Fox-Fordyce disease. "
4.	Hair Removal (Depilation) 06/01/2014 - "Fox Fordyce disease (FFD) has been recently described as an adverse effect of laser hair removal. " 06/01/2014 - "Fox Fordyce disease as a secondary effect of laser hair removal." 07/01/2013 - "Two recent reports indicated laser hair removal as a novel cause of axillary Fox-Fordyce disease. " 05/01/2011 - "Fox-Fordyce disease following axillary laser hair removal."
5.	Semiconductor Lasers 07/01/2013 - "We describe a case of Fox-Fordyce disease that developed in a 27-year-old woman 3 months after she had completed two LightSheer Diode laser treatments of her axilla, periumbilical region, and bikini area. "