Foot-and-Mouth Disease

03/01/1985 - "Improved foot and mouth disease (FMD) vaccines which have increased efficiency and stability are highly desirable. "
03/01/2009 - "Although present conventional foot-and-mouth disease (FMD) vaccines can prevent clinical disease, protection is short lived ( approximately 6 months), often requiring frequent revaccination for prophylactic control, and vaccination does not induce rapid protection against challenge or prevent the development of the carrier state. "
03/01/2014 - "Inactivated conventional vaccines against foot-and-mouth disease (FMD) are used routinely in endemic countries and are effective against clinical disease. "
01/01/2015 - "Foot-and-mouth disease: overview of motives of disease spread and efficacy of available vaccines."
09/15/2014 - "Inactivated whole virus foot-and-mouth disease (FMD) vaccines are used worldwide for protection against FMD, but not all vaccines induce protection against all genetic variants of the same FMD virus serotype. "

04/01/2012 - "Protection against foot-and-mouth disease (FMD) using DNA technology has been documented for sheep and pigs but not for the highly susceptible species of cattle. "
08/01/2011 - "Improved immune response by ID-pVAC: a secretory DNA vaccine construct delivered by PLG micro particles against foot and mouth disease in guinea pigs."
01/01/2005 - "DNA vaccine has been tested for protection against foot-and-mouth disease. "
04/01/2012 - "In this review, we provide a comprehensive overview of DNA vaccination strategies for foot-and-mouth disease reported in the literature, in which we highlight the studies that have reported protection in the key target species."
09/01/2006 - "DNA vaccination against foot-and-mouth disease via electroporation: study of molecular approaches for enhancing VP1 antigenicity."

01/01/1976 - "Studies about the adjuvant activity of saponin fractions in foot and mouth disease vaccine. "
06/01/1973 - "Studies about the adjuvant activity of saponin fractions in foot and mouth disease vaccine. "
10/01/2012 - "Increased humoral immune responses of pigs to foot-and-mouth disease vaccine supplemented with ginseng stem and leaf saponins."
06/01/1967 - "[On several tests of the value of saponin used alone as an adjuvant in the preparation of foot-and-mouth disease vaccine]."
03/01/1965 - "[On the active immunization of swine against foot-and-mouth disease using saponin vaccine]."

01/01/1977 - "A foot-and-mouth disease trivalent vaccine composed of strains A24 Cruzeiro, O1 Caseros and C2 Resende elicited no immune response in swine when adjuvanted with aluminium hydroxide but was effective when emulsified in oil. "
12/13/2008 - "Ten male Arabian oryx (Oryx leucoryx) were vaccinated with a commercially available standard aqueous foot-and-mouth-disease vaccine containing aluminium hydroxide as an adjuvant, and their antibody titres against serotypes O and A were measured using solid-phase blocking elisa and the virus neutralisation test. "
07/01/1970 - "Immunological studies with cell cultured aluminium hydroxide gel adsorbed formalin inactivated foot and mouth disease type Asia I monovalent vaccine."
10/01/2007 - "Outbreaks of foot-and-mouth disease (FMD) from January 1982 through December 2003 were used to examine variations in serotype- and species-specific risk for three control programmes in Colombia: (1982-1983) vaccination, using an aluminium hydroxide, saponin adjuvant, required but not enforced; (1984-1996) vaccination, using an oil double-emulsion adjuvant, required but not enforced; and (1997-2003) enforced vaccination, using an oil double-emulsion adjuvant, restricted animal movement enforced, and slaughter of infected animals. "
06/21/2002 - "Immune responses of goats against foot-and-mouth disease quadrivalent vaccine: comparison of double oil emulsion and aluminium hydroxide gel vaccines in eliciting immunity."

12/01/2010 - "The relationship of Foot-and-Mouth Disease (FMD) virus antigen payload and single and double vaccinations in conferring protection against virus challenge in sheep was studied. "
10/28/2010 - "In this study, foot-and-mouth disease (FMD) virus antigens were used to generate a genetic vaccine prototype. "
05/01/1986 - "Foot-and-mouth disease vaccination: a multifactorial study of the influence of antigen dose and potentially competitive immunogens on the response of cattle of different ages."
04/01/1966 - "[Preparation of concentrated foot-and-mouth disease antigen on cell culture for the study of 3 "O" type variants: O Flanders--O Sicily 58--O Spain 64]."
06/01/2015 - "Pan-Serotype Diagnostic for Foot-and-Mouth Disease Using the Consensus Antigen of Nonstructural Protein 3B."

12/01/2012 - "This study was designed to describe the status of foot and mouth disease (FMD) in Ethiopia, through analysis of FMD outbreak reports and the detection of antibodies, to address the possibility of establishing a disease-free zone. "
08/01/2011 - "In this study, a sandwich ELISA was developed for rapid detection of the foot-and-mouth disease (FMD) antibodies; it was based on an Escherichia coli-expressed, highly conserved region of the 3ABC nonstructural protein of the FMDV O/TW/99 strain and a monoclonal antibody derived from the expressed protein. "
01/01/2014 - "Maternal antibodies can interfere with foot-and-mouth disease vaccination. "
08/01/2010 - "Antibodies against foot-and-mouth disease (FMD) virus in African buffalos (Syncerus caffer) in selected National Parks in Uganda (2001-2003)."
01/01/2006 - "Evaluation of three 3ABC ELISAs for foot-and-mouth disease non-structural antibodies using latent class analysis."

02/01/1989 - "The resulting novel type of vaccine tripalmitoyl-S-glyceryl-cysteinylserylseryl-FMDV-VP1 (135-154) induces a long-lasting high protection against foot-and-mouth disease and serotype-specific virus-neutralizing antibodies in guinea-pigs after a single administration without any additional adjuvant or carrier. "
11/01/1962 - "Studies on the nature of the nature of the neutralization reaction and the competition for neutralizing antibody between components of the virus system of foot-and-mouth disease."
01/01/1992 - "A potency test method for foot and mouth disease vaccine based on the serum neutralizing antibody response produced in cattle."
01/01/1990 - "[Seasonal variations in the formation of virus-neutralizing antibodies in cattle after vaccination against foot-and-mouth disease]."
04/01/1987 - "Sources of variability in foot and mouth disease vaccine potency estimates based on serum neutralizing antibody assay."

09/01/1969 - "[Control of the activity of anti-foot-and-mouth disease GOA-formol vaccine on mice]."
09/01/1966 - "[On the immunizing properties of GOAL-formol vaccine and GNKI dry virus vaccine against foot-and-mouth disease]."
05/01/1972 - "[Efficacy of foot-and-mouth disease vaccine in pigs treated with formaldehyde GOA saponin prepared with A22 foot-and-mouth virus]."
07/01/1970 - "Immunological studies with cell cultured aluminium hydroxide gel adsorbed formalin inactivated foot and mouth disease type Asia I monovalent vaccine."
01/01/1999 - "The first experimental vaccines against foot-and-mouth disease were made in 1925 by Vallee, Carre and Rinjard using formaldehyde inactivation of tongue tissue from cattle infected with the virus. "

04/01/2012 - "Bovine type III interferon significantly delays and reduces the severity of foot-and-mouth disease in cattle."
10/01/2014 - "In recent years, we have developed novel strategies to control foot-and-mouth disease (FMD), including the use of biotherapeutics such as interferons (IFN) delivered by a replication-defective human adenovirus type 5 (Ad5). "
10/01/2014 - "Type III interferon protects swine against foot-and-mouth disease."
06/22/1963 - "Multiplication, interferon production and sensitivity of virulent and attenuated strains of the virus of foot-and-mouth disease."
10/01/2014 - "Several studies have demonstrated that the delivery of type I, II, or III interferons (IFNs) by inoculation of a replication-defective human adenovirus 5 (Ad5) vector expressing IFNs can effectively control foot-and-mouth disease (FMD) in cattle and swine during experimental infections. "

03/01/1999 - "Evidence of partial protection against foot-and-mouth disease in cattle immunized with a recombinant adenovirus vector expressing the precursor polypeptide (P1) of foot-and-mouth disease virus capsid proteins."
10/01/2015 - "Foot and mouth disease is caused by a non-enveloped virus (FMDV), which disposes several antigenic sites at the surface of their capsid proteins. "
12/01/2005 - "Non-capsid proteins to identify foot-and-mouth disease viral circulation in cattle irrespective of vaccination."
07/01/2002 - "A reverse transcription-dependent polymerase chain reaction (RT-PCR) is described that amplifies the genes encoding the capsid proteins VP1-3 of at least three evolutionary lineages each of the foot-and-mouth disease (FMD) virus types A, Asia1 and O. "
01/01/1993 - "Protection of swine against foot-and-mouth disease with viral capsid proteins expressed in heterologous systems."

03/01/2014 - "Human enterovirus 71 (EV71) is the major causative agent of severe hand-foot-and-mouth diseases (HFMD) in young children, and structural characterization of EV71 during its life cycle can aid in the development of therapeutics against HFMD. "
10/01/2012 - "Novel antiviral therapeutics to control foot-and-mouth disease."

02/01/2013 - "Enhancement of the immune responses to foot-and-mouth disease vaccination in mice by oral administration of a novel polysaccharide from the roots of Radix Cyathulae officinalis Kuan (RC)."
03/26/2009 - "Enhancement of the immune responses to vaccination against foot-and-mouth disease in mice by oral administration of an extract made from Rhizoma Atractylodis Macrocephalae (RAM)."

01/01/2009 - "Pig is used both for the prevention of foot-and-mouth disease and human diseases, sheep is a model for corneal transplantation, and the horse naturally develops arthritis. "

05/01/2004 - "A sloughed hoof in a young bull as a sequela of foot and mouth disease was treated by skin grafting. "

01/01/1953 - "[Foot-and-mouth disease; isotherapy, organotherapy and homeotherapy]."