Food Hypersensitivity (Food Allergy)

02/01/2012 - "Emerging studies are better designed to assess the true prevalence of IgE-mediated food allergy using formal population sampling frames, standardized and objective outcome data including use of the gold standard oral food challenge, and the capacity to adjust for potential selection bias."
03/01/2011 - "To determine whether specific oral tolerance induction (SOTI) is more effective than avoidance in inducing tolerance in children aged 0-18 years who have immunoglobulin E (IgE)-mediated food allergy. "
06/01/2003 - "Improved diagnostic methods include more precise in vitro and in vivo tests for immunoglobulin E-mediated food allergies, in vitro assays for predicting development of oral tolerance, and novel noninvasive tests for cell-mediated food allergies such as patch testing, cytokine assays, and detection of eosinophil activation markers. "
11/01/2011 - "This review found that OIT with cow's milk or egg is effective in achieving full tolerance or partial tolerance in the majority of patients with IgE mediated food allergy. "
10/01/2009 - "IFN-gamma-induced specific oral tolerance induction (ISOTI) is a promisingly effective treatment for IgE-mediated anaphylactic food allergy. "

09/01/2009 - "This review is dedicated to summarizing current knowledge about the most important food allergen protein families and to presenting data from the EuroPrevall allergen library, a proof-of-concept collection of highly purified, characterized and authenticated food allergens from animal and plant food sources to facilitate improved diagnosis of food allergies."
01/01/2013 - "This paper will discuss the use of animal models for the investigation of the major food allergens; cow's milk, hen's egg, and peanut/other tree nuts, highlight the distinguishing features of each of these models, and provide an overview of how the results from these trials have improved our understanding of these specific allergens and food allergy in general."
10/01/2015 - "FAHF-2 is a safe herbal medication for subjects with food allergy and shows favorable in vitro immunomodulatory effects; however, efficacy for improving tolerance to food allergens is not demonstrated at the dose and duration used."
02/01/2005 - "Results classified subjects into four groups according to the clinical history and prick-tests to common inhalants: group 1: subjects suspected of having a food allergy; group 2: subjects with ongoing atopic disease; group 3: subjects with an underlying predisposition to atopy, as showed by one or more positive results to prick-tests with airborne allergens; group 4: non atopic subjects. "
10/01/2009 - "However, with the improved understanding of tolerance and advances in characterization of food allergens, several therapeutic strategies have been developed and are currently being investigated as potential treatments and/or cures for food allergy."

08/01/2015 - "This unique pan-European birth cohort study using the gold standard diagnostic procedure for food allergies confirmed challenge-proven CMA in <1% of children up to age 2. Affected infants without detectable specific antibodies to cow's milk were very likely to tolerate cow's milk one year after diagnosis, whereas only half of those with specific antibodies in serum 'outgrew' their disease so soon."
01/01/1989 - "High levels of food antibodies in a colostrum sample seem not to offer protection against food allergy in the child."
12/15/2011 - "In these 19 dogs in which an elimination diet was used for the diagnosis of food allergy and in which 14 were probably food allergic and 7 were proven food allergic there were no significant differences in food-specific antibodies before and after an elimination diet of 6-8 weeks."
11/01/2002 - "In diagnostic tests, these antibodies are at the basis of many false-positive test results for food allergy. "
05/01/2000 - "pylori antibodies and AD as the sole manifestation of food allergy. "

01/01/2007 - "Nutritional management is directed towards the prevention of explicitly diet-related deficiencies, the mainstay of treatment of food allergy being strict avoidance of offending antigens in the diet. "
04/01/2000 - "Until now, blinded oral challenge procedures with food antigens have been accepted as the 'gold standard' in diagnosing food allergy, although these tests have practical problems. "
06/01/2015 - "Murine model studies are informing the development of novel live biotherapeutic approaches as an adjunctive therapy to enhance antigen-specific oral desensitization and to promote lasting tolerance in patients with food allergy. "
12/01/2014 - "The aim of this study was to investigate whether prolonged ingestion of antigen by sensitized mice would reverse the metabolic consequences caused by experimental food allergy. "
06/01/2009 - "This review documents the recent advance in the mechanistic study on concurrent use of microbial products and food antigens to study food allergy."

01/01/2006 - "Anti-IgE monoclonal antibody is the first potential therapy for food allergy that is under-going testing in clinical trials."
01/01/2014 - "This review focuses on non-allergen specific (anti-IgE, Chinese herbal formula, etc..) and allergen specific treatments for food allergy. "
12/01/2003 - "Response to "effect of anti-IgE therapy in patients with food allergy"."
08/01/2003 - "Effect of anti-IgE therapy in patients with food allergy."
07/01/2003 - "In food allergy patients, the density of eosinophils, the presence of intraepithelial eosinophils, and the rate of degranulation showed a highly significant correlation to the initial basal release of ECP by mucosal tissue (Kendall tau = 0.619, 0.381, and 0.609, respectively; p < 0.05 for all) but not to their capability to be stimulated with anti-IgE. "

09/01/2014 - "In addition, a combination of OIT with omalizumab, which was found to increase the threshold doses of the offending foods without producing adverse reactions, may be effective and useful in the treatment of food allergies. "
02/01/2013 - "Clinical trials using omalizumab in patients with food allergy resulted in achieving tolerance to higher amounts of the allergen in some patients. "
01/01/2015 - "Other novel approaches, including the use of omalizumab in combination with OIT, may be useful in food allergy treatment. "
01/01/2014 - "OIT combined with omalizumab increased the threshold doses of food without adverse reactions and may be of benefit in food allergy treatment. "
01/01/2014 - "These phase 1 data demonstrate that rush OIT to multiple foods with 16 weeks of treatment with omalizumab could allow for a fast desensitization in subjects with multiple food allergies. "

05/01/2013 - "Consequently, the patient gave positive results for all PR-10 proteins from birch, alder, hazel, apple, peach, peanut, hazelnut, and soybean, so we diagnosed him with Pollen Food Allergy Syndrome (PFAS) induced by cross reactivity with pollens of birch family and fruits of rose family. "
01/01/2015 - "We revealed in previous studies that nitration of food proteins reduces the risk of de novo sensitization in a murine food allergy model. "
08/01/2009 - "This article reviews recent studies that address one of the major unanswered questions in food allergy research: what attributes of food or food proteins contribute to or enhance food allergenicity?"
08/01/2008 - "The study aimed at detecting adults with food allergy to wheat and screening them for the presence of specific bronchial reactivity to inhaled wheat proteins. "
09/01/2003 - "Lipid transfer proteins (LTPs) are clinically relevant plant food panallergens and have been proposed as ideal tools to study true food allergy. "

12/01/2014 - "Strategies that favor IgG responses might prove useful in the management of food allergy."
01/01/2011 - "In this study we evaluated the clinical utility of specific IgG4 dosing against food in adult patients with suspected food allergy/intolerance. "
07/01/2000 - "This preliminary, descriptive study after extensive clinical experience demonstrates specific IgG food RASTs done in 114 consecutive patients with strong positive histories for delayed food allergy. "
11/01/1987 - "Long-term studies in prevention of food allergy: patterns of IgG anti-cow's milk antibody responses."
01/01/2015 - "Food hypersensitivities were determined by specific IgG ImmunoCAP(®) assays. "

07/01/1986 - "The efficacy of ketotifen in a controlled double-blind food challenge study in patients with food allergy."
07/01/1986 - "The results of this study suggest that ketotifen may be useful for some patients with food allergy."
07/01/1986 - "The effectiveness of oral ketotifen was compared with that of placebo in 26 patients with food allergy in a randomized, double-blind parallel study. "
03/01/1980 - "A study of the protective effect of ketotifen in food allergy."
11/01/1987 - "Ketotifen, benzocycloheptathiophene, (Zaditen) an orally active, anti-allergic and anti-asthmatic drug in a dose of 1 mg twice daily was given from 2 to 20 months in 20 selected patients with food allergy (FA) or food intolerance (FI). "

01/01/2012 - "The epitopes for OVA323-339-specific CD4⁺T cells from OVA23-3 food allergy model and DO11.10 tolerant induction model mice were analyzed. "
01/01/2011 - "The pathophysiology of food allergy (FA) relies on immune reactions triggered by epitopes, i.e. "
01/01/2010 - "The glycation structures of AGEs are suggested to function as pathogenesis-related immune epitopes in food allergy. "
01/01/2009 - "Characterization of allergenic epitopes provides fundamental knowledge for understanding mechanisms of food allergy. "
08/01/1999 - "In food allergy, sensitization and treatment are allergen specific; therefore, for primary prevention (avoiding sensitization) and secondary prevention of food allergy (avoiding symptoms in an already sensitized subject), a product without immunogenic and allergenic epitopes should be given in each case. "

01/01/2014 - "Additional bigger, multicentric and hopefully randomized-controlled studies must answer multiple questions including optimal dose, ideal duration of immunotherapy, degree of protection, efficacy for different ages, severity and type of food allergy responsive to treatment. "
06/01/2010 - "Additional studies must answer multiple questions including optimal dose, ideal duration of oral/sublingual immunotherapy, degree of protection, efficacy for different ages, severity and type of food allergy responsive to treatment and need for patient protection during home administration. "
01/01/2015 - "Oral immunotherapy (OIT) is a significant focus of food allergy research and appears to be effective in inducing desensitization. "
09/01/2014 - "Immunotherapy is a significant focus for treating food allergies, and oral immunotherapy (OIT) appears to be particularly effective in inducing desensitization. "
07/01/2015 - "Oral immunotherapy (OIT) may be an effective treatment for food allergy in children. "

05/24/2003 - "An interruption of oral contraception induced an increase of the C1-INH level from 0.201 to 0.224 g/L (p < 0.002) and of the C1-INH functional assay fom 0.396 to 0.702 U (p < 0.0001), associated with a recovery or a marked improvement of the clinical symptoms formerly ascribed to food allergy. "
03/14/2003 - "Discontinuation of oral contraception induced an increase in C1 INH levels and C1 INH activity, associated with recovery or marked improvement of the clinical symptoms formerly attributed to food allergy. "

08/01/2004 - "The data source was PubMed, using a search algorithm selecting for clinical studies of AEDS, diet therapy and food allergy in all children to October 2003. "
05/01/2000 - "Current concepts in the field of prophylaxis and diet therapy of food allergy are reviewed. "
07/01/1996 - "[Evaluation of IGF1 and IGFBP3 during diet therapy in patients with food allergy with complex nutritional risk]."
01/01/1996 - "[The characteristics of diet therapy for children with a food allergy]."
01/01/1995 - "[Use of a specialized product based on soya in diet therapy of food hypersensitivity]."

09/01/2011 - "Research on traditional Chinese medicine herbal medicines for treating food allergy is rare. "
06/01/2006 - "Food allergy specifically does not seem to be a disorder traditionally recognized in the traditional Chinese medicine literature. "
11/01/2005 - "To evaluate the immunoregulatory effects of the Lonicera water extract in the ovalbulmin (OVA)-sensitized BALB/c mice and to explore feasibility of treating food allergy with the traditional Chinese medicine (TCM). "
01/01/2014 - "A Traditional Chinese Medicine (TCM) formula prevents anaphylaxis in murine food allergy models, and has immunomodulatory effects in humans. "
09/01/2011 - "This review article discusses promising traditional Chinese medicine interventions for asthma, food allergy, and comorbid conditions, and explores their possible mechanisms of action."

07/01/2012 - "Since there is still no cure for food allergy, the only available treatment is strict avoidance of the culprit food and provision of emergency treatment. "
06/01/2014 - "The impact of the increase of food allergy has driven package labeling laws, legislation on emergency treatment availability in schools and other public places, and school policy. "
01/01/2009 - "Food allergy may be life-threatening and its management continues to consist of avoiding relevant allergens and, in the case of accidental ingestion, initiation of appropriate emergency therapy. "
12/01/2006 - "Food allergy may be life threatening and its management continues to consist of avoiding relevant allergens and, in the case of accidental ingestion, initiation of appropriate emergency therapy. "
05/01/2004 - "The management of food allergies continues to consist of educating patients on how to avoid relevant allergens, to recognize early symptoms of an allergic reaction in case of an accidental ingestion, and to initiate the appropriate emergency therapy. "