Flurbiprofen (Froben)

An anti-inflammatory analgesic and antipyretic of the phenylalkynoic acid series. It has been shown to reduce bone resorption in periodontal disease by inhibiting CARBONIC ANHYDRASE.
Also Known As:
Froben; Ansaid; Ocufen; 2-Fluoro-alpha-methyl-(1,1'-biphenyl)-4-acetic Acid; Abbott Brand of Flurbiprofen; Allergan Brand of Flurbiprofen Sodium; Apo-Flurbiprofen; Apotex Brand of Flurbiprofen; BTS-18322; Cantabria Brand of Flurbiprofen; Cebutid; Crookes Brand of Flurbiprofen; Dobrofen; E-7869; Flubiprofen; Flugalin; Flurbiprofen Sodium; Fluriproben; Froben SR; Klosterfrau Brand of Flurbiprofen; Knoll Brand of Flurbiprofen; Neo Artrol; Novo-Flurprofen; Novopharm Brand of Flurbiprofen; Nu-Flurbiprofen; Nu-Pharm Brand of Flurbiprofen; Ocuflur; Pfizer Brand of Flurbiprofen; Pharm-Allergan Brand of Flurbiprofen Sodium; Ratiopharm Brand of Flurbiprofen; Recordati Brand of Flurbiprofen; Shire Brand of Flurbiprofen; Strefen; ratio-Flurbiprofen; Apo Flurbiprofen; BTS 18322; BTS18322; E 7869; E7869; Flurbiprofen Pfizer Brand; Novo Flurprofen; Nu Flurbiprofen; Nu Pharm Brand of Flurbiprofen; Pharm Allergan Brand of Flurbiprofen Sodium; Sodium, Flurbiprofen; ratio Flurbiprofen; (1,1'-Biphenyl)-4-acetic acid, 2-fluoro-alpha-methyl-
Networked: 623 relevant articles (90 outcomes, 151 trials/studies)

Relationship Network

Drug Context: Research Results


1. Geisslinger, Gerd: 4 articles (11/2014 - 07/2003)
2. Tegeder, Irmgard: 4 articles (11/2014 - 07/2003)
3. Fujii, Yoshitaka: 4 articles (04/2009 - 01/2004)
4. Del Soldato, P: 4 articles (09/2004 - 09/2001)
5. Bishay, Philipp: 3 articles (11/2014 - 01/2010)
6. Häussler, Annett: 3 articles (11/2014 - 01/2010)
7. Shephard, Adrian: 3 articles (02/2014 - 02/2013)
8. Chen, Yao: 3 articles (12/2013 - 05/2013)
9. Sun, Jianfei: 3 articles (12/2013 - 05/2013)
10. Lehmann, Jochen: 3 articles (12/2013 - 05/2013)

Related Diseases

1. Pain (Aches)
03/24/1986 - "Using the highly sensitive dental pain model, flurbiprofen appears to be an effective, peripherally acting analgesic with a rapid onset of activity. "
03/01/2002 - "The efficacy of flurbiprofen 8.75 mg lozenge over placebo was confirmed: there was a significant difference in pain relief obtained from flurbiprofen 8.75 mg versus placebo, along with a significant reduction of difficulty in swallowing from the time of first assessment and significantly greater reductions in throat soreness and difficulty in swallowing throughout the study period. "
04/10/2014 - "Flurbiprofen in 15 mg/kg and 40 mg/kg doses significantly improved pain tolerance measured by tail flick test (tail flick in FBP15 and FBP40 groups: 96.hour vs 97.hour, 7.01±4.97 vs 8.34±3.61 and 5.06±1.57 vs 7.04±2.49, p<0.05 for both). "
02/01/2013 - "A significant reduction in pain intensity was found in both groups; the average visual analog scale (VAS) score was reduced from 7.8 to 3.0 in the control group and from 7.9 to 2.2 in the flurbiprofen group (P<0.01). "
01/01/1994 - "On day 7, spontaneous pain (the prime efficacy parameter), as evaluated by the patient on a visual analogue scale in the physician's office, showed significant improvement in the 40 mg flurbiprofen patch group compared to control (change from baseline) (p = 0.039), a result corroborated by the evaluation of the periarticular oedema: a reduction of 77.4% was observed in the 40 mg flurbiprofen patch group, compared with 63.8% in the control group (p = 0.025). "
2. Cataract (Cataracts)
3. Postoperative Pain
4. Osteoarthritis
5. Inflammation

Related Drugs and Biologics

1. Indomethacin (Indometacin)
2. Diclofenac (SR 38)
3. Flurbiprofen (Froben)
4. Aspirin (Acetylsalicylic Acid)
5. Naproxen (Naprosyn)
6. Acetaminophen (Paracetamol)
7. Piroxicam (Feldene)
8. Lidocaine (Xylocaine)
9. Morphine (MS Contin)
10. Propofol (Diprivan)

Related Therapies and Procedures

1. Injections
2. Oral Administration
3. Cataract Extraction
4. Intraocular Lens Implantation
5. Angioplasty (Angioplasty, Transluminal)