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Floxuridine (FUdR)

An antineoplastic antimetabolite that is metabolized to fluorouracil when administered by rapid injection; when administered by slow, continuous, intra-arterial infusion, it is converted to floxuridine monophosphate. It has been used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in malignant neoplasms of the liver and gastrointestinal tract.
Also Known As:
FUdR; Fluorodeoxyuridine; 5 Fluorodeoxyuridine; 5-FUdR; 5-Fluorodeoxyuridine; Uridine, 2'-deoxy-5-fluoro-
Networked: 690 relevant articles (63 outcomes, 117 trials/studies)

Relationship Network

Drug Context: Research Results

Experts

1. Kim, Hye-Sook: 13 articles (11/2020 - 01/2002)
2. Sato, Akira: 13 articles (11/2020 - 01/2006)
3. Wataya, Yusuke: 13 articles (11/2020 - 01/2002)
4. Xiang, Yang: 12 articles (12/2021 - 08/2003)
5. Hiramoto, Akiko: 12 articles (11/2020 - 01/2006)
6. Jarnagin, William R: 10 articles (01/2022 - 07/2009)
7. Kemeny, Nancy E: 9 articles (01/2022 - 05/2009)
8. Satake, Akito: 9 articles (01/2016 - 01/2006)
9. D'Angelica, Michael I: 8 articles (01/2022 - 01/2011)
10. Fong, Yuman: 7 articles (02/2013 - 08/2005)

Related Diseases

1. Neoplasm Metastasis (Metastasis)
2. Colorectal Neoplasms (Colorectal Cancer)
3. Neoplasms (Cancer)
4. Renal Cell Carcinoma (Grawitz Tumor)
5. Trophoblastic Neoplasms (Trophoblastic Tumor)

Related Drugs and Biologics

1. Floxuridine (FUdR)
2. Pharmaceutical Preparations
3. Fluorouracil (Carac)
4. Irinotecan (Camptosar)
5. Mitomycin (Mitomycin-C)
6. Oxaliplatin (Eloxatin)
7. Leucovorin (Folinic Acid)
8. Dexamethasone (Maxidex)
9. 5-fluoro-2'-deoxyuridine
10. Etoposide (VP 16)

Related Therapies and Procedures

1. Drug Therapy (Chemotherapy)
2. Therapeutics
3. Catheters
4. Infusion Pumps (Infusion Pump)
5. Laparotomy