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Floxacillin (Flucloxacillin)

Subscribe to New Research on Floxacillin

Antibiotic analog of CLOXACILLIN.

Also Known As:

Flucloxacillin; Fluorochloroxacillin; 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 6-(((3-(2-chloro-6-fluorophenyl)-5-methyl-4-isoxazolyl)carbonyl)amino)-3,3-dimethyl-7-oxo-, (2S-(2alpha,5alpha,6beta))-

Networked: 249 relevant articles (25 outcomes, 34 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Daly, Ann K: 5 articles (02/2014 - 12/2008)
2.	Pirmohamed, Munir: 5 articles (02/2013 - 06/2009)
3.	Howden, Benjamin P: 3 articles (01/2016 - 05/2002)
4.	Park, B Kevin: 3 articles (02/2013 - 06/2009)
5.	O'Sullivan, Matthew V N: 2 articles (01/2016 - 08/2011)
6.	Robinson, James O: 2 articles (01/2016 - 08/2011)
7.	Roberts, Jason A: 2 articles (10/2014 - 08/2010)
8.	Lipman, Jeffrey: 2 articles (10/2014 - 08/2010)
9.	O'Sullivan, Ronan: 2 articles (06/2014 - 01/2013)
10.	Wakai, Abel: 2 articles (06/2014 - 01/2013)

Related Diseases

1.	Infection 01/01/1999 - "Further studies are needed to identify whether continuous-infusion flucloxacillin can entirely replace intermittent-dose therapy for such infections." 10/01/2014 - "Owing to the complicated nature of the infection, sequential concentrations of free flucloxacillin were measured in plasma and cerebrospinal fluid (CSF) and used to direct antibiotic dosing. " 11/01/2009 - "To determine the usefulness of flucloxacillin as empirical therapy for putative Staphylococcus aureus infections in intensive care unit (ICU) patients in the Netherlands, the antibiotic resistance of S. " 11/01/2009 - "Flucloxacillin, still the empirical choice for putative Staphylococcus aureus infections in intensive care units in the Netherlands." 09/01/2007 - "Flucloxacillin is often used for the treatment of serious infections due to sensitive staphylococci. "
2.	Endocarditis 04/01/2015 - "We investigated whether at this temperature, mecC-MRSA strains respond to flucloxacillin treatment like MSSA strains, using a rat model of endocarditis. " 04/01/2015 - "In vivo effect of flucloxacillin in experimental endocarditis caused by mecC-positive staphylococcus aureus showing temperature-dependent susceptibility in vitro." 12/01/2013 - "Severe bleeding as a result of platelet inhibition caused by floxacillin treatment for endocarditis." 05/01/1995 - "Treatment with an aminoglycoside plus flucloxacillin is commonly used to prevent wound infection and endocarditis after cardiac surgery. " 09/01/2007 - "A 73-year-old woman with endocarditis was treated with flucloxacillin and rifampicin. "
3.	Staphylococcal Infections 04/23/1977 - "These studies showed that 18-hour diffusion sensitivity tests indicate the clinical value of treatment with flucloxacillin for staphylococcal infections of moderate severity more correctly at 37 degrees C than at 30 degrees C." 07/01/2010 - "These data support current Australian recommendations for the use of flucloxacillin or a first-generation cephalosporin as initial treatment of non-life-threatening staphylococcal infections. " 08/01/1994 - "In addition, flucloxacillin (1-2 g every 4 h) could be added if there was clinical suspicion of staphylococcal infection. " 08/01/1993 - "In addition, flucloxacillin (1-2 g, every 4 h) could be added if there was clinical suspicion of staphylococcal infection (17 in each arm). " 01/01/1986 - "A total of twenty-nine children were admitted to the paediatric unit with confirmed or presumed staphylococcal infection and subsequently treated with the narrow spectrum antibiotic--flucloxacillin. "
4.	Cellulitis 01/01/2014 - "Those who have improved substantially (defined as being afebrile, and having a lower cellulitis severity score) will be randomized at day 6 between additional 6 days of oral flucloxacillin (n = 198) or placebo (n = 198). " 01/01/2013 - "This trial aims to establish the non-inferiority of flucloxacillin monotherapy to dual therapy in the treatment of uncomplicated cellulitis among ED patients. " 08/01/2007 - "The cellulitis responded to oral flucloxacillin. " 08/01/2001 - "The efficacy of continuous infusion flucloxacillin in home therapy for serious staphylococcal infections and cellulitis." 01/01/1989 - "Facial cellulitis responsive to flucloxacillin in acute leukemia."
5.	Wound Infection (Wound Infections) 12/01/2015 - "Two patients developed a superficial wound infection, which was resolved with oral flucloxacillin. " 10/01/2013 - "Use of routine prophylactic flucloxacillin did not significantly reduce incidence of post-MMC wound infection (odds ratio, 0.6; 95% confidence interval, 0-1.2). " 10/01/2013 - "Wound infection was present in 0.7% (5 of 646) of flucloxacillin recipients and 1.2% (8 of 645) of non-recipients (P = .4). " 10/01/2011 - "Six of 36 patients (17%) reported wound infection in the placebo group, and four of 34 (12%) in the flucloxacillin group, P=0.736. " 11/01/2006 - "The administration of a single dose of flucloxacillin failed to reduce the rate of wound infection after non-reconstructive breast surgery."

Related Drugs and Biologics

1.	Vancomycin
2.	Teicoplanin
3.	Methicillin (Metin)
4.	Anti-Bacterial Agents (Antibiotics)
5.	Cloxacillin (Tegopen)
6.	Amoxicillin (Wymox)
7.	Fusidic Acid (Fucithalmic)
8.	Amoxicillin-Potassium Clavulanate Combination (Co-amoxiclav)
9.	Aztreonam
10.	Gentamicins (Gentamicin)

Related Therapies and Procedures

1.	Hip Replacement Arthroplasty (Total Hip Replacement)
2.	Intensive Care (Surgical Intensive Care)
3.	Continuous Ambulatory Peritoneal Dialysis (CAPD)
4.	Intravenous Infusions
5.	Antibiotic Prophylaxis