Ficain

A sulfhydryl proteinase with cysteine at the active site from ficus latex. Preferential cleavage is at tyrosine and phenylalanine residues. EC 3.4.22.3.

Also Known As:

Networked: 28 relevant articles (3 outcomes, 3 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Artyukhov, Valeriy G: 2 articles (12/2020 - 01/2017)
2.	Baidamshina, Diana R: 2 articles (12/2020 - 01/2017)
3.	Bogachev, Mikhail I: 2 articles (12/2020 - 01/2017)
4.	Holyavka, Marina G: 2 articles (12/2020 - 01/2017)
5.	Kayumov, Airat R: 2 articles (12/2020 - 01/2017)
6.	Ieong, H F-H: 1 article (08/2022)
7.	Kumowski, N: 1 article (08/2022)
8.	LaMotte, R H: 1 article (08/2022)
9.	Malewicz, N M: 1 article (08/2022)
10.	Oeck, S: 1 article (08/2022)

Related Diseases

1.	Carcinoma (Carcinomatosis) 07/01/1988 - "The authors performed a study of the effect of ficin in 110 paraffinized specimens, including tonsil, lymph nodes, benign vascular and nerve sheath tumors, and various carcinomas and sarcomas. " 04/01/1994 - "Aim of the present study was to investigate the efficacy of 4 different proteolytic treatments (Ficin, Protease type XIV, Microwave irradiation in Citrate buffer and Microwave irradiation in Lead Tiocyanate), compared to the incubation with buffer only, for the detection of cytokeratins in 10 cases of carcinomas from different organs. "
2.	Infections 12/01/2020 - "Taken together, our data suggest that both soluble and immobilized Ficin appear beneficial for the treatment of biofilm-associated infections, as well as speeding up wound healing and microbial decontamination."
3.	Hemorrhage 11/13/2022 - "Conclusions: A pharmacological approach using a high dose of oral supplementation with MFEs (bromelain, papain, and ficin) was effective in reducing vitreous opacities, even after intraocular hemorrhage. "
4.	Nerve Sheath Neoplasms (Nerve Sheath Neoplasm) 07/01/1988 - "The authors performed a study of the effect of ficin in 110 paraffinized specimens, including tonsil, lymph nodes, benign vascular and nerve sheath tumors, and various carcinomas and sarcomas. "
5.	Sarcoma (Soft Tissue Sarcoma) 07/01/1988 - "The authors performed a study of the effect of ficin in 110 paraffinized specimens, including tonsil, lymph nodes, benign vascular and nerve sheath tumors, and various carcinomas and sarcomas. " 07/01/1988 - "Pepsin was comparatively less active than ficin and bromelain overall but did produce the greatest amplification of vimentin staining in sarcomas. "

Related Drugs and Biologics

1.	Peptide Hydrolases (Proteases)
2.	Bromelains (Bromelain)
3.	Citric Acid (Citrate)
4.	Buffers
5.	Papain
6.	Enzymes
7.	Latex
8.	alpha-Galactosidase (Beano)
9.	Cysteine Proteases (Cysteine Protease)
10.	Cathepsin L

Related Therapies and Procedures

1.	Platelet Transfusion (Blood Platelet Transfusions)
2.	Therapeutics