Fibromuscular Dysplasia

An idiopathic, segmental, nonatheromatous disease of the musculature of arterial walls, leading to STENOSIS of small and medium-sized arteries. There is true proliferation of SMOOTH MUSCLE CELLS and fibrous tissue. Fibromuscular dysplasia lesions are smooth stenosis and occur most often in the renal and carotid arteries. They may also occur in other peripheral arteries of the extremity.
Also Known As:
Dysplasia, Fibromuscular; Dysplasias, Fibromuscular; Fibromuscular Dysplasias
Networked: 298 relevant articles (13 outcomes, 18 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Renal Artery Obstruction (Renal Artery Stenosis)
2. Hypertension (High Blood Pressure)
3. Renovascular Hypertension (Goldblatt Syndrome)
4. Pathologic Constriction (Stenosis)
5. Atherosclerotic Plaque (Atheroma)


1. Zeller, Thomas: 5 articles (01/2014 - 12/2004)
2. Sandmann, W: 3 articles (07/2010 - 12/2002)
3. Voiculescu, A: 3 articles (07/2010 - 12/2002)
4. Cohen, José E: 2 articles (11/2014 - 08/2007)
5. Kalva, Sanjeeva P: 2 articles (06/2014 - 08/2013)
6. Gulati, Rajiv: 2 articles (05/2014 - 01/2014)
7. Grabitz, Klaus: 2 articles (04/2014 - 02/2003)
8. Saw, Jacqueline: 2 articles (04/2014 - 01/2014)
9. Rastan, Aljoscha: 2 articles (01/2014 - 11/2009)
10. Zeller, T: 2 articles (03/2011 - 08/2006)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Fibromuscular Dysplasia:
1. ReninIBA
2. Progesterone Receptors (Progesterone Receptor)IBA
3. FibrinIBA
4. alpha 1-Antitrypsin (alpha 1 Antitrypsin)IBA
5. glucuronyl glucosamine glycan sulfate (Vessel)IBA
6. CollagenIBA
7. Phenobarbital (Luminal)FDA Link
8. Oral ContraceptivesIBA
9. Mesenteric vascular diseaseIBA
10. Cocaine (Cocaine HCl)IBA
09/01/2007 - "More intriguingly, the case suggests a possible relationship between in utero cocaine exposure and the development of fibromuscular dysplasia in the child."
09/01/2007 - "Fibromuscular dysplasia in association with intrauterine cocaine exposure."
01/01/2014 - "RAT has both cardiogenic etiology (arrhythmia, endocarditis, valvular heart disease, coronary disease) and noncardiogenic etiology (renal artery injury and/or instrumentation, fibromuscular dysplasia, coagulation disorders, homocystinuria, cocaine intake). "
01/01/2015 - "Non-cardiovascular conditions were connective tissue disorders, fibromuscular dysplasia, Ehlers-Danlos syndrome, Marfan's syndrome, sarcoidosis, Crohn's disease, polycystic kidney disease, rheumatoid arthritis, vasculitis including giant cell arteritis, polyarteritis nodosa and Takayasu's disease, cocaine use, early or premature labor. "
04/01/1996 - "The reported risk factors of this age group are cardiopathies, hypertension, smoking, hypercholesterolemia, reduction of anticoagulant proteins, hypercoagulable states, antiphospholipid antibodies primary syndrome, antiphospholipid antibodies secondary syndrome, some hemoglobinopathies, hyperviscosity syndromes, vasculitis, collagen vascular diseases, fibromuscular dysplasia, arterial dissections, migraine, myopathy encephalopathy lactic acidosis stroke like episodes, homocystinuria, familial amyloid angiopathy, microangiopathy with retinopathy encephalopathy and deafness, systemic lupus erythematosus, use of cocaine, traumas or manipulations of neck, AIDS. "

Therapies and Procedures

1. Angioplasty (Angioplasty, Transluminal)
2. Balloon Angioplasty
3. Transplants (Transplant)
4. Balloon Dilation
5. Denervation