Fenoprofen (Fenoprofen Calcium)

01/01/1983 - "After 7 days there was no significant difference between the efficacy of the two drugs with respect to 'pain at rest', 'pain on movement', 'tenderness' or 'sleep disturbance' but fenoprofen was significantly better when considering 'limitation of movement' and 'The physician's assessment of the severity of the condition'. "
01/01/2011 - "The NNT for at least 50% pain relief over 4 to 6 hours with a single dose of fenoprofen 200 mg compared to placebo was 2.3 (1.9 to 3.0). "
11/15/1983 - "[Fenoprofen as a treatment of postsurgical pain]."
01/01/2011 - "Oral fenoprofen 200 mg is effective at treating moderate to severe acute postoperative pain, based on limited data for at least 50% pain relief over 4 to 6 hours. "
05/01/1984 - "The relative analgesic efficacy of zomepirac sodium 100 mg and fenoprofen calcium 200 mg was evaluated in patients with pain due to surgical removal of dental impactions. "

01/01/1976 - "Some problems in the interpretation of clinical trials: longterm parallel study of fenoprofen in rheumatoid arthritis."
01/01/1976 - "Fenoprofen, a new antirheumatic agent, was evaluated in 45 patients with rheumatoid arthritis in an open study design to simulate the conditions under which the drug will be used. "
01/01/1976 - "Fenoprofen in rheumatoid arthritis: a controlled crossover multi-centre study."
02/02/1974 - "Fenoprofen, a compound with analgesic, anti-inflammatory, and antipyretic properties in animals, has been compared with placebo in a double-blind cross-over trial in 60 patients with rheumatoid arthritis. "
05/05/2007 - "Stereoselective disposition of fenoprofen in plasma and synovial fluid of patients with rheumatoid arthritis."

06/01/1974 - "Two studies on 41 patients with osteoarthrosis of the hip or knee have shown fenoprofen-a compound with analgesic and anti-inflammatory properties-to be an effective addition to the drug treatment of these conditions. "
01/01/1988 - "Enteric-coated fenoprofen in large-joint osteoarthritis."
01/15/1983 - "6X with fenoprofen in osteoarthritis of the hip and knee, fenoprofen was shown to have beneficial analgesic and anti-inflammatory effects which differed significantly from those of placebo. "
01/01/1981 - "Plasma levels after single doses of 300 mg and 600 mg fenoprofen were measured in 10 elderly patients with osteoarthritis. "
01/01/1980 - "Fenoprofen in the treatment of osteoarthrosis of hips and knee joints in the elderly."

12/01/1985 - "Efficacy of fenoprofen in the treatment of primary dysmenorrhea."
12/01/1985 - "Our study lends support to the concept of a "plateau analgesic effect" of nonsteroidal antiinflammatory drugs (NSAIDs): fenoprofen, 200 mg, appears to be as effective as fenoprofen, 400 mg. When this type of drug fails to provide relief for a woman suffering from primary dysmenorrhea, switching to another NSAID may be more appropriate than increasing the dosage and the probability of dosage-related side effects."
12/01/1985 - "We compared fenoprofen calcium, 200 mg; fenoprofen calcium, 400 mg; aspirin, 650 mg; and a placebo in 85 women for the relief of primary dysmenorrhea in a double-blind, clinical trial. "
01/01/1983 - "Comparison of fenoprofen calcium, ibuprofen and placebo in primary dysmenorrhea."
01/01/1983 - "This prospective, double-blind, parallel, two clinic study compared fenoprofen calcium, 200 mg; ibuprofen, 400 mg; and placebo in the treatment of pain due to primary dysmenorrhea. "

05/05/2007 - "The simultaneous disposition of fenoprofen enantiomers in synovial fluid and plasma was studied in 11 patients with arthritis and chronic knee effusions treated with a single oral dose of 600 mg rac-fenoprofen. "
10/01/2004 - "The results indicate that experimental diabetes and adjuvant-induced arthritis influence the fenoprofen enantioselective metabolism."
10/01/2004 - "Enantioselective kinetic disposition of fenoprofen in rats with experimental diabetes or adjuvant-induced arthritis."
10/01/2004 - "This study was aimed to investigate the influence of diabetes or arthritis on the enantioselective metabolism and kinetic disposition of fenoprofen in rats with streptozotocin-induced diabetes or Mycobacteriumtuberculosis adjuvant-induced arthritis. "
01/01/1979 - "Newer nonsteroidal antiinflammatory agents (NSAI's) such as ibuprofen, neproxen, fenoprofen, and tolmetin have broadened the therapeutic choice and increased the chances of providing optimum arthritis control, but require careful assessment of the possibilities for unwanted drug effects when long-term therapy is required. "