Fats

The glyceryl esters of a fatty acid, or of a mixture of fatty acids. They are generally odorless, colorless, and tasteless if pure, but they may be flavored according to origin. Fats are insoluble in water, soluble in most organic solvents. They occur in animal and vegetable tissue and are generally obtained by boiling or by extraction under pressure. They are important in the diet (DIETARY FATS) as a source of energy. (Grant & Hackh's Chemical Dictionary, 5th ed)

Networked: 1479 relevant articles (38 outcomes, 159 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Willett, Walter C: 13 articles (10/2015 - 07/2002)
2.	La Vecchia, Carlo: 11 articles (10/2013 - 02/2002)
3.	Bosetti, Cristina: 7 articles (10/2013 - 02/2002)
4.	Negri, Eva: 7 articles (10/2013 - 06/2002)
5.	Hu, Frank B: 6 articles (10/2015 - 07/2005)
6.	Qiu, Li: 5 articles (01/2015 - 01/2010)
7.	Zhang, Jun: 5 articles (01/2015 - 01/2010)
8.	Li, Zheng: 5 articles (01/2015 - 01/2010)
9.	Franceschi, Silvia: 5 articles (10/2013 - 06/2002)
10.	La Vecchia, C: 5 articles (07/2012 - 03/2001)

Related Diseases

1.	Body Weight (Weight, Body) 07/01/2013 - "Indeed, data from analytical and experimental studies indicated a relation between increased consumption of some food categories such as fruits and vegetables, fiber and whole grains, fish, and moderate consumption of alcohol and reduced risk of major chronic degenerative diseases, whereas increased total caloric intake, body weight, meat, and fats are associated with greater risk. " 08/01/1999 - "Postprandial samples were taken on day 21, 3 h after lunch (n 18), and on the last day of the study 2, 4, 6 and 8 h after a fat load containing 1.2 g of one of the milk fats/kg body weight (n 8). " 04/01/1993 - "Although FO fats ate slightly less total energy than the other groups, there were no differences among groups in body weight at any time during the study. " 10/01/1985 - "As part of this study, two fats, varying in fatty acid composition, were also compared but found not to affect significantly body weight gain or feed efficiency. " 11/01/2014 - "The control group showed 17% greater body weight and 20% more epididymal fats compared with the vaccinated group. "
2.	Atherosclerosis 04/20/1999 - "Intensive lipid-lowering therapy in the Familial Atherosclerosis Treatment Study (FATS) resulted in significant improvement in CAD. " 09/01/2014 - "Prolonged combination lipid therapy is associated with reduced carotid intima-media thickness: a case-control study of the 20-year Familial Atherosclerosis Treatment - Observational Study (FATS-OS)." 03/01/2007 - "Epidemiologic studies and clinical trials have shown that diet and, in particular, the consumption of fats, influence the body's metabolism and can affect the development of atherosclerosis and resulting cardiovascular repercussions. " 02/26/1998 - "Patients in the original Familial Atherosclerosis Treatment Study (FATS) cohort were subgrouped into those with triglyceride levels < or = 120 mg/dL (n = 26) and those with triglyceride levels > or = 190 mg/dL (n = 40). " 01/01/1993 - "In the Familial Atherosclerosis Treatment Study (FATS), the reduction in clinical events (75%) far outweighed the modest frequency and magnitude of lesion regression observed among those receiving intensive lipid-lowering therapy. "
3.	Neoplasms (Cancer) 08/01/2014 - "This study investigates the use of demographic and clinical variables to create an easy scoring system for predicting adrenal tumor functionality (functional adrenal tumors, or FATs). " 01/01/2013 - "A diet completely free of fats cannot be easily administered to humans, but experimental studies in mice can be done to determine whether this extreme condition influences tumor development. " 01/01/2012 - "Recent studies of FATS (for Fragile-site Associated Tumor Suppressor), a new CACG at FRA10F, reveal an active role of this CACG in regulating DNA damage checkpoints and suppressing tumorigenesis. " 05/01/1998 - "The purpose of this study was to determine whether the fats exert their effects by altering the expression of genes that affect cancer development. " 09/01/1993 - "However, the influence of animal fats is seen both in animal studies and epidemiological studies of breast and bowel cancer. "
4.	Coronary Disease (Coronary Heart Disease) 01/01/2015 - "Potential of trans fats policies to reduce socioeconomic inequalities in mortality from coronary heart disease in England: cost effectiveness modelling study." 03/01/1996 - "More controlled studies are needed to assess definitely the impact of different hydrogenated fats on risk of coronary heart disease." 01/01/1968 - "[Value of the study of resorption of labelled fats in coronary disease]." 08/15/2014 - "That there could now be seriously conflicting scientific opinion over the role of saturated fats in the aetiopathogenesis of coronary heart disease is a terrifying indictment of our limited understanding of the role of the modern diet in disease. " 01/01/2013 - "Advice to substitute polyunsaturated fats for saturated fats is a key component of worldwide dietary guidelines for coronary heart disease risk reduction. "
5.	Hypertension (High Blood Pressure) 08/01/1999 - "The Dietary Approaches to Stop Hypertension (DASH) clinical trial demonstrated that a diet that emphasizes fruits, vegetables, and low-fat dairy products, includes whole grains, nuts, fish, and poultry, and is reduced in fats, red meats, sweets, and sugar-containing beverages can be highly effective in lowering blood pressure. " 07/01/1999 - "The Dietary Approaches to Stop Hypertension (DASH) diet, rich in fruits, vegetables, nuts, and low-fat dairy foods, with reduced saturated and total fats, was found in clinical trials to lower blood pressure substantially and significantly. " 11/01/2015 - "We developed the Facilitators of and Barriers to Adherence to Hypertension Treatment Scale (FATS) with input from focus groups with 20 AA women. " 09/01/2015 - "An adherence score was computed by comparing consumption frequency of 10 food groups (fruits, vegetables, total dairy, low-fat dairy, meat, total grains, high-fiber grains, legumes, fats, sweets) from the Dietary Approaches to Stop Hypertension (DASH) diet guidelines. " 02/01/2011 - "Prudent (higher intake of fruits, vegetables, legumes, fish, poultry, and whole grains), Western (higher intake of red and processed meats, saturated fats, and sweets), and Dietary Approach to Stop Hypertension (DASH)-style dietary patterns (also greater intake of vegetables, fruits, and whole grains). "

Related Drugs and Biologics

1.	Carbohydrates
2.	Cholesterol
3.	Oils
4.	Glucose (Dextrose)
5.	Omega-3 Fatty Acids (Omega 3 Fatty Acids)
6.	Unsaturated Fatty Acids (Polyunsaturated Fatty Acids)
7.	Fatty Acids (Saturated Fatty Acids)
8.	Dietary Fats (Ghee)
9.	Proteins (Proteins, Gene)
10.	Antioxidants

Related Therapies and Procedures

1.	Transplants (Transplant)
2.	Suction (Suction Drainage)
3.	Parenteral Nutrition
4.	Estrogen Replacement Therapy
5.	Mediterranean Diet