Fat Necrosis

10/01/1978 - "[Studies of lipase-induced fat necrosis in rats (author's transl)]."
01/01/1946 - "Fat necrosis studies; the effect of feeding lipase-containing vegetable seed on the production of fat necrosis."
12/01/1945 - "Fat necrosis studies; the effect of soybean and peanut feeding on the blood and urine lipase of rabbits and in the production of fat necrosis."
03/01/2015 - "Lipase inhibition reduced fat necrosis, UFAs, organ failure, and mortality but not the parameters of AP induction. "
08/01/1990 - "We report positive intracellular staining of adipocytes with a monoclonal antibody to pancreatic lipase in a lesion of subcutaneous pancreatic fat necrosis, and confirm the role of pancreatic lipase in the pathogenesis of this syndrome."

09/01/1992 - "Inasmuch as edema and fat necrosis are not important determinants of severity, these observations could explain the poor prognostic value of serum amylase activity in patients with acute pancreatitis."
12/01/1975 - "Within a few hours after one injection of fresh human serum by the intraperitoneal route only, mice developed pancreatic acinar cell necrosis and inflammation, fat necrosis, elevated serum amylase and a shocklike state. "
09/01/1992 - "Serum amylase correlated best with edema (r = 0.61) and fat necrosis (r = 0.58), less well with acinar necrosis (r = 0.53) and inflammation (r = 0.50), and poorly with hemorrhage (r = 0.33) and perivascular infiltrate (r = 0.31). "
05/01/1992 - "The lavage alone is followed by a marked decrease of fat necrosis and amylase and lipase activity in serum. "
02/01/1991 - "Its severity was evaluated by the degree of extrapancreatic fat necrosis, the increase in serum amylase and lipase activities, and by histologic investigations. "

07/01/2013 - "Fat necrosis in the breast from methylene blue dye injection."
11/28/2005 - "Skin and fat necrosis of the breast following methylene blue dye injection for sentinel node biopsy in a patient with breast cancer."
07/01/2013 - "While deemed safe and effective, methylene blue dye has been associated with infection, fibrosis, and skin and fat necrosis. "
08/01/1955 - "[Metabolic functions of tocopherols (alpha & gamma) and comparison with methylene blue in experimental steatonecrosis induced by carbon tetrachloride]."

09/01/1988 - "Efficacy of isoprothiolane for the treatment of fat necrosis in cattle."
10/01/1988 - "Therapeutic effect of isoprothiolane on bovine fat necrosis."

01/01/2016 - "Fat necrosis was experienced by 14 (48.2%) patients in the DIEP group, and 4 (17.4%) patients in the DIEP-TAsc group (P = 0.020). "
06/01/2015 - "Fat necrosis develops in breast aesthetic surgery (breast reduction) or reconstructive breast surgery (after abdominal flaps like TRAM or DIEP). "
02/01/2014 - "Both DIEP and muscle-sparing free TRAM flap reconstructions had much higher rates of fat necrosis when irradiated. "
02/01/2014 - "There were no differences in fat necrosis rates between the DIEP and muscle-sparing free TRAM flaps in both the irradiated and nonirradiated groups. "
02/01/2014 - "Irradiated flaps (i.e., both DIEP and muscle-sparing free TRAM flaps) developed fat necrosis at a significantly higher rate (22.5 percent) than the nonirradiated flaps (9.2 percent; p = 0.009). "

10/01/2013 - "Imaging features of fat necrosis vary depending on its stage of evolution and can mimic malignancy in late stages. "
03/01/2013 - "The radiographic and clinical significance of fat necrosis of the breast is that it may mimic malignancy. "
10/01/2012 - "Mammary fat necrosis may closely mimic breast neoplasia, both clinically and radiographically, and is thus frequently biopsied. "
12/01/2011 - "Although most of the changes suggest fat necrosis, an irregular parenchymal mass can develop and mimic a recurrence."
11/01/2008 - "Fat necrosis may mimic malignancy with varying appearances on MRI. "

04/01/2010 - "Influence of the recipient vessel on fat necrosis after breast reconstruction with a free transverse rectus abdominis myocutaneous flap."
05/01/2004 - "With HE staining, the tissue sections from the study group revealed new vessel formation with small diameter, increase in the reactional mesenchymal tissue, granulation tissue, degeneration of the striated muscle fibers, dystrophic calcifications, fat necrosis, and coagulation necrosis (ischemic necrosis). "
12/01/2007 - "Despite this, the incidences of flap loss, fat necrosis, and mastectomy skin flap necrosis were not significantly different between the internal mammary and internal mammary perforator vessel groups. "
06/01/2000 - "In summary, free TRAM flap breast reconstruction in smokers was not associated with a significant increase in the rates of vessel thrombosis, flap loss, or fat necrosis compared with rates in nonsmokers. "
02/01/2014 - "RA-CA causes structural injury to the RA with evidence of histological injury (including intimal hyperplasia, periarterial tissue/fat necrosis and adventitial inflammation) along with intimal tears and medial dissections evident along the entire length of the vessel. "

05/01/2015 - "This study investigated which zonal tissue would be more secure from the risk of fat necrosis between Holm zones II and III and examined the risk factors of fat necrosis in a clinical series of medial row perforator-based deep inferior epigastric artery perforator (DIEP) flaps. "

06/01/2005 - "In previous studies, we have demonstrated that Kupffer cells isolated from rats with CCl4-induced steatonecrosis produced more reactive oxygen intermediates than cells isolated from normal rats. "

01/01/1986 - "The histopathological study of lymphatic organs structure did not reveal any specific changes but the symptoms of focal degeneration and fat necrosis were found in livers of mice born from ampicillin treated mothers. "

09/01/2013 - "To investigate the significance and images characters of ultrasound and mammography in the diagnosis of fat necrosis after fat transplantation in breasts(FTB). "
09/01/2013 - "[The significance of ultrasound and mammography in the diagnosis of fat necrosis after fat transplantation in breasts]."
01/01/2000 - "Early work with fat transplantation, when the fat was injected subcutaneously or transplanted in bulk, was disappointing with significant loss of volume from central fat necrosis. "
05/01/1998 - "Four of the cases developed two to six days after transplantation, but in the fifth case, fat necrosis developed ten months after transplantation. "
03/01/1989 - "Transplantation of a large amount of fat will result in fat necrosis. "

09/01/2002 - "A lower rate of partial flap (fat) necrosis is associated with microvascular free-flap transfer compared with the conventional (unipedicled) TRAM flap because of its potentially improved blood supply. "
02/01/2013 - "Fat tissue can be injured by ischaemia in free flap surgeries, leading to the development of fat necrosis. "
01/01/2008 - "Our data demonstrated that the incidence of partial flap loss and fat necrosis in the microvascularly augmented group was significantly lower than that in the unipedicled flap group (P < 0.01), and also lower than that in the free flap group with a statistically marginal significance (P = 0.055). "
12/01/2005 - "For the free flap group, two patients (13.3%) developed complete flap loss, but none suffered fat necrosis. "
04/01/2014 - "Fat necrosis is one of the most common complications following free flap breast reconstruction. "

09/01/2010 - "Patient demographics and complications were identified, including initial size of fat necrosis, number of ultrasound-assisted liposuction treatments, and final size of fat necrosis. "
09/01/2010 - "The article describes a case series of patients with fat necrosis treated with ultrasound-assisted liposuction. "
06/01/2008 - "UAL is safer and less invasive than traditional treatments for fat necrosis including direct excision and suction-assisted liposuction."
08/01/1996 - "Liposuction will improve the silhouette in most patients, but an open approach may be required where fat necrosis and heterotopic calcification have occurred."
09/01/2010 - "This case series describes the successful use of ultrasound-assisted liposuction for treatment of fat necrosis after autologous breast reconstruction. "

02/01/2015 - "A classification system for fat necrosis in autologous breast reconstruction."
10/01/2013 - "Fat necrosis requiring excision was present in 5.2 percent of breast reconstructions, and there were three flap losses (2.2 percent). "
05/01/2013 - "Compromised perfusion in autologous breast reconstruction results in fat necrosis and flap loss. "
05/01/2013 - "Fat necrosis (FN) is a common complication of autologous breast reconstruction, yet no classification system exists to describe it. "
05/01/2013 - "A classification system for fat necrosis in autologous breast reconstruction."

11/01/2007 - "Fat necrosis after partial-breast irradiation with brachytherapy or electron irradiation versus standard whole-breast radiotherapy--4-year results of a randomized trial."
04/01/2015 - "Brachytherapy patients trended towards more frequent biopsies as a result of fat necrosis to rule out a recurrence (11.2 vs. 6.7 %, p = 0.13). "
02/01/2015 - "To investigate the incidence of and potential risk factors for fat necrosis in high dose-rate (HDR) balloon-based breast brachytherapy (BBB). "
02/01/2015 - "The incidence of fat necrosis in balloon-based breast brachytherapy."
11/01/2007 - "To examine the incidence and clinical relevance of fat necrosis after accelerated partial-breast irradiation (PBI) using interstitial high-dose-rate brachytherapy (HDR-BT) in comparison with partial-breast electron irradiation (ELE) and whole-breast irradiation (WBI). "