Premature Cardiac Complexes (Extrasystoles)

A group of cardiac arrhythmias in which the cardiac contractions are not initiated at the SINOATRIAL NODE. They include both atrial and ventricular premature beats, and are also known as extra or ectopic heartbeats. Their frequency is increased in heart diseases.
Also Known As:
Extrasystoles; Extrasystole; Premature Beats; Cardiac Complexes, Premature; Cardiac Complex, Premature; Premature Cardiac Complex; Beat, Premature; Beats, Premature; Complexes, Premature Cardiac; Ectopic Heartbeat; Heartbeat, Ectopic; Heartbeats, Ectopic; Premature Beat; Premature Cardiac Complices; Ectopic Heartbeats
Networked: 814 relevant articles (43 outcomes, 48 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Ventricular Tachycardia
2. Ventricular Premature Complexes (Premature Ventricular Contraction)
3. Tachycardia (Tachyarrhythmias)
4. Atrial Fibrillation
5. Ischemia


1. Antzelevitch, Charles: 6 articles (11/2013 - 01/2003)
2. Curtis, Michael J: 3 articles (12/2015 - 03/2006)
3. Liu, Zhi Jun: 3 articles (01/2013 - 01/2010)
4. Liu, Zhao Lan: 3 articles (01/2013 - 01/2010)
5. Liu, Jian Ping: 3 articles (01/2013 - 01/2010)
6. Yan, Gan-Xin: 3 articles (09/2011 - 08/2004)
7. Razumov, A N: 3 articles (03/2009 - 07/2002)
8. Klemenkov, S V: 3 articles (03/2009 - 07/2002)
9. Verrier, Richard L: 3 articles (10/2008 - 08/2004)
10. Dianat, Mahin: 2 articles (03/2015 - 01/2015)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Premature Cardiac Complexes:
1. Propafenone (Rythmol)FDA LinkGeneric
2. Anti-Arrhythmia AgentsIBA
3. Amiodarone (Amiodarona)FDA LinkGeneric
4. Caffeine (No Doz)FDA LinkGeneric
5. Flecainide (Tambocor)FDA LinkGeneric
6. Mexiletine (Mexitil)FDA LinkGeneric
7. Quinidine (Chinidin)FDA LinkGeneric
8. Isoproterenol (Isoprenaline)FDA LinkGeneric
9. allapininIBA
10. CalciumIBA

Therapies and Procedures

1. Drug Therapy (Chemotherapy)
04/01/2011 - "Usually, no drug therapy is needed for the management of supraventricular or ventricular premature beats but potential promoting factors should be eliminated. "
03/01/1996 - "Individualized antiarrhythmic drug therapy for patients with ventricular tachyarrhythmias may be selected by the noninvasive approach (suppression of spontaneous ventricular premature beats) or the invasive approach (suppression of ventricular tachyarrhythmias induced at an electrophysiologic study). "
01/21/1984 - "Drug therapy of ventricular arrhythmias in patients with cardiac disease sets out to lower the incidence of sudden death and should be used only for dangerous arrhythmias (ventricular premature beats of Lown classes 3 to 5) and in patients with significant heart disease. "
04/01/1988 - "Multivariate regression analysis identified 4 variables as independent predictors of sudden cardiac death: rales (p = 0.009), the number of runs of VT during exercise testing while receiving antiarrhythmic drug therapy (p = 0.0003), a history of congestive heart failure (p = 0.0009) and the number of premature beats on Holter monitoring (p = 0.01). "
01/01/2009 - "Anthracycline chemotherapy, which represents the treatment of choice for many hematologic and metastatic cancers, unfortunately carries with it the possibility of both early cardiotoxic phenomena, occuring during chemotherapy, and also late cardiotoxic manifestations, occuring even months or years from the completion of treatment.THE CLINICAL MANIFESTATIONS OF EARLY CARDIOTOXICITY COMMONLY INCLUDE: ventricular premature beats, supraventricular tachycardia, cardiomyopathy and sudden death.This"
2. Baths
3. Ligation
4. Cardiopulmonary Bypass (Heart-Lung Bypass)
5. Catheters