Ethyl Ether (Ether)

A mobile, very volatile, highly flammable liquid used as an inhalation anesthetic and as a solvent for waxes, fats, oils, perfumes, alkaloids, and gums. It is mildly irritating to skin and mucous membranes.

Also Known As:

Networked: 2312 relevant articles (51 outcomes, 172 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Kline, Kimberly: 14 articles (12/2012 - 05/2003)
2.	Sanders, Bob G: 14 articles (12/2012 - 05/2003)
3.	Ueoka, Ryuichi: 12 articles (09/2014 - 11/2002)
4.	Gong, Qiuming: 11 articles (04/2014 - 08/2004)
5.	Zhou, Zhengfeng: 11 articles (04/2014 - 08/2004)
6.	Camacho, Javier: 10 articles (01/2015 - 02/2006)
7.	Matsumoto, Yoko: 10 articles (09/2014 - 11/2002)
8.	Sener, Göksel: 10 articles (09/2012 - 05/2002)
9.	Yu, Weiping: 8 articles (12/2012 - 12/2004)
10.	Mollinedo, Faustino: 7 articles (05/2015 - 10/2002)

Related Diseases

1.	Neoplasms (Cancer) 02/01/2009 - "For investigating the overall lipophilicity of the molecule, the 3-O-hexyl ether group present at position-3 of purpurinimide 5 was replaced with a methyl ether substituent, and the resulting product 10 showed improved tumor uptake, but due to its significantly higher uptake in the liver, spleen, and other organs, a poor tumor contrast in whole-body tumor imaging was observed." 11/25/1994 - "rac-ET-18-OCH3 (1) with its R and S enantiomeric forms, 2 and 3, respectively, exhibited modest stereoselectivity in HUT 78 and Namalwa with 1 and 2 slightly more cytotoxic than 3. Ether lipid (EL) analogs 4, 5, and 6 demonstrated significantly greater cytotoxicity in normal peripheral lymphocytes, 4 and 6 exhibited a modest increase in cytotoxicity in HUT 78 and Namalwa (P < 0.05), and 5 demonstrated greater cytotoxicity (P < 0.05) in Namalwa than the parent EL 1. The calculated 24 h ID50 values suggest that the beta-methyl analogs, 9 and 10, were more cytotoxic than the alpha-methyl analogs, 7 and 8, in all the tested cancer cell lines." 11/26/2015 - "This 1b study assessed safety, imaging characteristics, and possible antineoplastic properties and provided further proof-of- concept of phospholipid ether analogues' retention within tumors. " 11/20/2015 - "Previous studies have reported that lowering ether lipid levels by genetic ablation of the ether lipid-generating enzyme alkyl-glycerone phosphate synthase (AGPS) lowers key structural and oncogenic ether lipid levels and alters fatty acid, glycerophospholipid, and eicosanoid metabolism to impair cancer pathogenicity, indicating that AGPS may be a potential therapeutic target for cancer. " 04/01/2015 - "Human ether-a-go-go related gene (herg) encoding HERG K(+) channel has been demonstrated in many previous studies with its association to cell cycle progression and growth in tumor cells. "
2.	Infection 05/01/2014 - "We compared the accuracy of the Kato-Katz method and ether-concentration technique for the diagnosis of soil-transmitted helminth infections within a randomised controlled trial. " 05/01/2014 - "Comparison of the Kato-Katz method and ether-concentration technique for the diagnosis of soil-transmitted helminth infections in the framework of a randomised controlled trial." 01/01/1981 - "As part of an investigation of intestinal parasitic infections of rural Kenyan people, a study was undertaken to examine variations in faecal egg counts and to assess the sensitivity of the ether sedimentation technique of faecal processing in the diagnosis of helminth infections. " 09/01/2015 - "Infection with PRRSV markedly reduced final BW, ADG, and ADFI ( < 0.01) and reduced efficiencies of ADF and ether extract utilization ( = 0.05 and = 0.02, respectively) regardless of vaccination status. " 05/01/2014 - "The ether-concentration method showed similar or slightly higher sensitivity than the Kato-Katz technique based on a single stool sample for all soil-transmitted helminth infections. "
3.	Carcinoma (Carcinomatosis) 05/01/1992 - "In this study, we present data which indicate that this exogenous molecule altered the endogenous synthesis of the neutral ether, ester-sn-glycerols, in 2 variant cell lines of a rat colon carcinoma. " 01/01/1966 - "[Study of the cytostatic action of an alpha-glyceryl-ether on T 8 carcinoma in rats]." 06/14/2006 - "To determine the potential role of phytochemicals associated with the RPI, we studied in vitro antitumor activities of an ether fraction from RPI using human tumor cell lines, including two human breast carcinoma cell lines (MDA-MB-453 and MCF-7) and two myeloma cell lines (RPMI-8226 and IM-9). " 06/01/1997 - "Synergistic cytotoxic effects of ether phospholipid analogues and ionizing radiation in human carcinoma cells." 05/01/1992 - "The 1-O-octadecyl-2-O-methyl-sn-glycero-3-phosphocholine causes a differential incorporation of hexadecanol into neutral ether ester glycerolipids of 2 variant cell lines of rat colon carcinoma."
4.	Stupor 03/20/1931 - "(4) The application of ether, alcohol, or xylol to the 3 posterior pairs of spiracles, or immersion of these segments in alcohol, was effective in inducing premature reversal at the close of the 5th stage, exclusively forward beating being resumed as soon as narcosis disappeared. " 03/01/2013 - "3 days after the last CP administration the rats were weighted and blood under ether narcosis has been taken for biochemical examination. " 01/01/2012 - "Nowadays, in Russia, diethyl ether is the most popular narcosis for rodent and particular rats. " 05/01/2011 - "Total of 36 white rats, male, body mass 130-150 g., underwent partial resection of the spleen under the ether narcosis. " 12/01/2010 - "After stopping of the experiment (15th day), under the ether narcosis the animals were sacrificed. "
5.	Postherpetic Neuralgia 10/01/1998 - "Topical application of a mixture of acetylsalicylic acid (ASA) and diethyl ether is effective in the treatment of acute herpes zoster and postherpetic neuralgia. " 05/01/1998 - "Skin and plasma levels of acetylsalicylic acid: a comparison between topical aspirin/diethyl ether mixture and oral aspirin in acute herpes zoster and postherpetic neuralgia." 04/01/1997 - "Comments on De Benedittis and Lorenzetti: on topical aspirin/diethyl ether for postherpetic neuralgia, PAIN, 65 (1996) 45-51." 05/01/1998 - "This was done by comparing skin and plasma levels of acetylsalicylic acid (ASA) and salicylic acid (SA) after topically administered ASA/diethyl ether (ADE) mixture in acute herpetic neuralgia (AHN) and postherpetic neuralgia (PHN). " 04/01/1996 - "Topical aspirin/diethyl ether mixture versus indomethacin and diclofenac/diethyl ether mixtures for acute herpetic neuralgia and postherpetic neuralgia: a double-blind crossover placebo-controlled study."

Related Drugs and Biologics

1.	Formaldehyde (Formol)
2.	cidofovir (Vistide)
3.	Halothane (Fluothane)
4.	Antigens
5.	maleic acid (maleate)
6.	methoxyethylene-maleic anhydride copolymer
7.	Triclosan (pHisoHex)
8.	Ethyl Ether (Ether)
9.	Aspirin (Acetylsalicylic Acid)
10.	Sodium Fluoride (Ossin)

Related Therapies and Procedures

1.	Anesthesia
2.	Bone Marrow Transplantation (Transplantation, Bone Marrow)
3.	Aftercare (After-Treatment)
4.	Autologous Transplantation
5.	Neuroleptanalgesia