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Non-Steroidal Estrogens (Estrogens, Non Steroidal)

Non-steroidal compounds with estrogenic activity.

Also Known As:

Estrogens, Non Steroidal; Estrogens, Non-Steroidal; Estrogens, Nonsteroidal; Nonsteroidal Estrogens

Networked: 10 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Chemical Actions and Uses
- Pharmacologic Actions: 160
  - Physiological Effects of Drugs: 1
    - Hormones, Hormone Substitutes, and Hormone Antagonists
      - Hormones: 80400
        Estrogens: 41480
        Non-Steroidal Estrogens: 10
        Phytoestrogens: 1571

Experts

1.	Chi, Dae Yoon: 2 articles (05/2009 - 05/2007)
2.	Katzenellenbogen, John A: 2 articles (05/2009 - 05/2007)
3.	An, Gwangil: 1 article (05/2009)
4.	Carlson, Kathryn E: 1 article (05/2009)
5.	Cheon, Gi Jeong: 1 article (05/2009)
6.	Choi, Tae Hyun: 1 article (05/2009)
7.	Kim, Jung Young: 1 article (05/2009)
8.	Koh, Hun Yeong: 1 article (05/2009)
9.	Lee, Kyo Chul: 1 article (05/2009)
10.	Moon, Byung Seok: 1 article (05/2009)

Related Diseases

1.	Neoplasms (Cancer) 02/01/1997 - "Human exposure to nonsteroidal estrogens in the environment has recently been proposed as a risk factor for endocrine disruption and the development of cancers of the breast and reproductive tract. " 06/07/1976 - "The malignant tumors and adenosis have been associated with the maternal ingestion of nonsteroidal estrogens - stilbesrol or one of its closely related compounds. " 06/01/1999 - "This result confirms our opinion that the strong in vivo activity of this drug on hormone-sensitive breast cancers is mediated by its estrogenic potency by analogy with high dosed steroidal and non-steroidal estrogens. " 01/01/2002 - "Phytoestrogens, plant-derived nonsteroidal estrogens found in high abundance in most soy food products, have been studied for their potential beneficial effects against hormone-dependent cancers and age-related diseases. "
2.	Breast Neoplasms (Breast Cancer) 01/01/1994 - "Synthesis, receptor binding and in vivo distribution of two non-steroidal estrogens as potential breast tumor imaging agents." 05/01/2007 - "C4-[18F]Fluorocyclofenil ([18F]FCF, 6) and C3-[18F]fluoroethylcyclofenil ([18F]FECF, 9), two high-affinity nonsteroidal estrogens, were prepared and investigated as potential agents for imaging estrogen receptors (ERs) in breast tumors. " 05/01/2009 - "We have investigated halogen-substituted non-steroidal estrogens with selective binding affinity for the estrogen receptor beta (ERbeta that might be used for imaging the levels of this ER-subtype in breast tumors by positron emission tomography (PET). " 09/01/1980 - "Steroidal and nonsteroidal estrogens substituted with halogens ortho to the phenolic hydroxyl group in the D ring at C-16 have been prepared as potential estrogen receptor-based imaging agents for human breast tumors. "
3.	Neurodegenerative Diseases (Neurodegenerative Disease) 01/01/2003 - "Together, these data demonstrate that a variety of steroidal and non-steroidal estrogens are potent neuroprotective agents in an animal model of global ischemia, agents that protect neurons critical for learning and memory and susceptible to neurodegenerative diseases."
4.	Clear Cell Adenocarcinoma 05/01/1979 - " In 1971, a Registry of Clear Cell Adenocarcinoma of the Genital Tract in Young Females was established, and shortly thereafter the Food and Drug Administration warned that DES and chemically related nonsteroidal estrogens were contraindicated during pregnancy. "
5.	Ischemia 01/01/2003 - "Together, these data demonstrate that a variety of steroidal and non-steroidal estrogens are potent neuroprotective agents in an animal model of global ischemia, agents that protect neurons critical for learning and memory and susceptible to neurodegenerative diseases."

Related Drugs and Biologics

1.	Estrogen Receptors
2.	Hormones (Hormone)
3.	Halogens
4.	Phytoestrogens (Phytoestrogen)
5.	Estrogen Receptor beta
6.	Neuroprotective Agents
7.	Hydroxyl Radical