Esters

02/01/2005 - "Both in vitro and in vivo anti-tumor activity studies for these esters were conducted and the data demonstrated positive results, that is, these esters were active against the tested tumor lines. "
05/20/1999 - "This represents an improvement in both efficiency and potency over the dialkyl ester prodrug strategy in which the inhibitor is indirectly delivered into tumor cells as the [glycyl,glutamyl] diethyl or dicyclopentyl esters. "
06/15/2012 - "Simple, fast and efficient synthesis of β-keto esters from the esters of heteroaryl compounds, its antimicrobial study and cytotoxicity towards various cancer cell lines."
01/01/2005 - "The current study indicates that methyl esters might be a promising chemopreventive and chemotherapeutic agent for treating various forms of cancer by causing apoptosis and proliferation inhibition."
01/01/1982 - "The findings of the present and other studies (4,7) show that TPA and other tumor-promoting esters suppress various in vitro manifestations of natural cell-mediated tumor resistance: (a) prevention of enhancement of macrophage cytocidal activity; (b) suppression of cytocidal capacity by activated macrophages; and (c) suppression of cytolytic activity of NK cells. "

12/01/2014 - "Taken together our results showed for the first time that daucane esters induces apoptotic cell death through a ROS-mediated mechanism in human leukemia cells. "
05/01/2013 - "The effects of P- and HG-alkyl (C4-C18) esters (0.1-100μM) on human leukemia T (Jurkat) cells viability and plasma membrane fluidity were evaluated. "
05/01/2008 - "The synthesis and the in vivo evaluation against leukemias P388 and L1210 of six new alkylating steroidal esters are described. "
02/01/2003 - "Esters 5b and 5c demonstrated great abilities to inhibit growth of the leukemia cells followed by induction of apoptosis; esters 5a, 5e, and 5g induced slight perturbations in the cell cycle at high concentrations; and esters 5d, 5f, and 5h were completely inactive against the cell lines tested. "
02/01/2003 - "Eight 9NC esters 5a-5h were tested for cytotoxicity against human leukemia cell lines HL-60 and U-937. "

04/01/2013 - "The first series of compounds investigated, β-lactam phosphate esters 7a, 8a and 9a, exhibited potent antiproliferative activity and caused microtubule disruption in human breast carcinoma-derived MCF-7 cells. "
01/01/2006 - "Thirty-two new esters of ALA were prepared and their ability to induce porphyrin formation was assessed in the WiDr human carcinoma cell line in vitro and in the normal skin of Balb/c nude mice in vivo. "
12/29/2000 - "Human carcinoma MCF-7 cells failed to express the 5-kb LRAT transcript and to synthesize retinyl esters. "
05/30/1991 - "In the human breast carcinoma cell line, MCF-7, in which the cytostatic effects of butyric esters were the most pronounced, cells accumulated in the G0/G1 phase of the cell cycle. "
08/01/1957 - "[Effect of aliphatic dinitro esters on Ehrlich carcinoma]."

01/01/2008 - "In this review, results from selective published trials with cocoa and chocolate focused on risk for CVD will be discussed along with a study we recently completed evaluating the effects of the daily consumption of flavanol-containing dark chocolate (CocoaVia?) with and without plant sterol esters on CVD markers in a normotensive population with mild hypercholesterolemia. "
01/01/2014 - "Osmotic fragility data suggested that the erythrocyte membrane of hypercholesterolemia was relatively more fragile than that of the normal rats' membrane which could be reversed with the addition of sterol esters in the diet. "
03/01/2013 - "The results suggest that phytosterol esters may be of therapeutic significance and may offer new and effective options for the treatment of hypercholesterolemia-induced changes in the brain."
04/01/2011 - "Effects of prescription omega-3-acid ethyl esters on fasting lipid profile in subjects with primary hypercholesterolemia."
03/01/2007 - "To evaluate the effect of three less explored low-fat milk products enriched with plant stanol esters on serum lipid concentrations in subjects with mild or moderate hypercholesterolemia. "

04/01/2007 - "Plant stanol esters are potentially cost-effective in the prevention of coronary heart disease in men: Bayesian modelling approach."
05/14/2011 - "One gram day of omega-3-acid ethyl esters added to the usual cardiologic treatment in patients with coronary heart disease improves pro BNP levels of patients with preserved left ventricular function without modifying serum inflammatory parameters."
04/01/2007 - "A Bayesian modelling approach was applied to synthesize clinical evidence and evaluate the cost-effectiveness (Euro/quality-adjusted life years) of plant stanol esters in spread in the prevention of coronary heart disease based on published FINRISK and 4S risk functions. "
04/01/2007 - "The cost-effectiveness of plant stanol esters in the prevention of coronary heart disease, however, has remained unevaluated. "
06/01/2002 - "Omega-3 fatty acid ethyl esters increase heart rate variability in patients with coronary disease."