Ergocalciferols (Ergocalciferol)

Derivatives of ERGOSTEROL formed by ULTRAVIOLET RAYS breaking of the C9-C10 bond. They differ from CHOLECALCIFEROL in having a double bond between C22 and C23 and a methyl group at C24.

Also Known As:

Networked: 490 relevant articles (28 outcomes, 50 trials/studies)

Relationship Network

Drug Context: Research Results

Experts

1.	Sato, Yoshihiro: 6 articles (12/2011 - 01/2005)
2.	Iwamoto, Jun: 6 articles (12/2011 - 01/2005)
3.	Thacher, Tom D: 5 articles (09/2014 - 12/2006)
4.	Singh, Rakesh K: 4 articles (11/2013 - 01/2011)
5.	Brard, Laurent: 4 articles (11/2013 - 01/2011)
6.	Kanoko, Tomohiro: 4 articles (07/2006 - 01/2005)
7.	Satoh, Kei: 4 articles (07/2006 - 01/2005)
8.	Pettifor, John M: 3 articles (09/2014 - 12/2006)
9.	Fischer, Philip R: 3 articles (09/2014 - 12/2006)
10.	Kalantar-Zadeh, Kamyar: 3 articles (03/2014 - 09/2009)

Related Diseases

1.	Vitamin D Deficiency 12/01/1996 - "To determine the efficacy of a single oral dose of 150,000 IU of vitamin D2 at the beginning of autumn for preventing winter vitamin D deficiency in children in Ushuaia (55 degrees S). " 01/01/2015 - " studies compared ergocalciferol in patients with CKD and vitamin D deficiency. " 07/15/2005 - "The results of this study demonstrate that a majority of adults with CF have serum 25-OHD levels below 30 ng/ml, and the currently recommended ergocalciferol repletion regimen often does not fully correct vitamin D deficiency and may need to be revised to include even higher dosing of ergocalciferol. " 10/01/2015 - "Vitamin D deficiency or insufficiency is an independent risk factor for VAD in HD patients; its treatment with ergocalciferol is associated with decreased VAD. " 01/01/2015 - "Effects of a 10-day course of a high dose calciferol versus a single mega dose of ergocalciferol in correcting vitamin D deficiency."
2.	Osteomalacia 11/01/1987 - "Both patients were treated with very large doses of vitamin D2 and phosphate without improvement in the osteomalacia or normalization of the serum phosphate. " 04/01/1982 - "The efficacy of vitamin D2 in the dose of 2000 IU daily in reversing anticonvulsant osteomalacia was studied in nine epileptic inpatients. " 01/01/1984 - "A possible role of vitamin D2 in producing osteomalacia is not easy to understand since normal serum levels of 25(OH)-D2, the circulating form of vitamin D2, have been reported. " 08/01/1978 - "Ca infusion (1500 mg/m2/12 h) induced an increase in serum P level to 3.2 mg/100 ml, in tubular phosphate reabsorption from 72 to 90%, while serum iPTH decreased to 33 micron1Eq/ml. Vitamin D2 administration (45 mg) resulted in increased 25-OHCC concentration to 28 ng/ml and in healing of pelvic osteomalacia. " 01/01/1977 - "Effect of long-term vitamin D2 treatment on bone morphometry and biochemical values in anticonvulsant osteomalacia."
3.	Rickets (Rachitis) 01/01/1975 - "Severe rickets which had not responded to large amounts (greater than 200 mg in total) of vitamin D2 was markedly cured with 2.5 mug of 1alpha-OH-D3 given daily for 3 weeks. " 09/01/2010 - "We administered an oral single dose of vitamin D(2) or D(3) of 1.25 mg to 49 Nigerian children--28 with active rickets and 21 healthy controls. " 12/01/2006 - "We administered vitamin D(2), 50,000 IU orally to 16 Nigerian children 15 to 48 months of age with radiographically active rickets. " 09/01/2000 - "once) at 4 mo of age, followed by oral supplementation of 400 IU vitamin D2 daily until weaning, prevents rickets in juvenile chimpanzees raised indoors." 07/01/1981 - "Mild morphological lesions of rickets developed in several boars not receiving supplemental vitamin D2 and in boars supplemented with 100 an 300 IU/kg of feed."
4.	Cystic Fibrosis (Mucoviscidosis) 03/01/2010 - "Transient effectiveness of vitamin D2 therapy in pediatric cystic fibrosis patients." 03/01/2001 - "Diminished and erratic absorption of ergocalciferol in adult cystic fibrosis patients." 07/01/2009 - "Very high-dose ergocalciferol is effective for correcting vitamin D deficiency in children and young adults with cystic fibrosis." 07/15/2005 - "Failure of high-dose ergocalciferol to correct vitamin D deficiency in adults with cystic fibrosis." 10/01/2008 - "To determine the prevalence of vitamin D deficiency (25-hydroxy vitamin D [25-OHD] levels in plasma <30 ng/mL) in pediatric patients with cystic fibrosis (CF), elucidate contributing factors for vitamin D deficiency, and determine the efficacy of ergocalciferol repletion strategies. "
5.	Kidney Diseases (Kidney Disease) 01/01/2013 - "Our aim was to evaluate the efficacy of prescribing ergocalciferol supplementation based on KDOQI guidelines for chronic kidney disease (CKD) stages III-IV in HD patients. " 03/01/2013 - "Ergocalciferol treatment and aspects of mineral homeostasis in patients with chronic kidney disease stage 4-5." 01/01/2013 - "An ergocalciferol-prescribing strategy using the KDOQI guidelines for stage III-IV kidney disease in HD patients with VitD deficiency or insufficiency is inadequate to achieve repletion or maintenance of normal VitD levels." 02/01/2012 - "Ergocalciferol (or a matched placebo) was given daily as per Kidney Disease Outcomes Quality Initiative guidelines. " 01/01/2014 - "Ergocalciferol improved microcirculatory endothelial function in patients with chronic kidney disease and concomitant vitamin D deficiency. "

Related Drugs and Biologics

1.	Vitamin D
2.	Cholecalciferol (Vitamin D3)
3.	hydroxide ion
4.	Calcium
5.	Ergocalciferols (Ergocalciferol)
6.	25-hydroxyvitamin D
7.	Calcifediol (Calcidiol)
8.	1-hydroxycholecalciferol (alfacalcidol)
9.	Alkaline Phosphatase
10.	Phosphorus

Related Therapies and Procedures

1.	Renal Dialysis (Hemodialysis)
2.	Gastrectomy
3.	Aftercare (After-Treatment)
4.	Heterologous Transplantation (Xenotransplantation)
5.	Oral Administration