Ephemeral Fever

An Ephemerovirus infection of cattle caused by bovine ephemeral fever virus (EPHEMERAL FEVER VIRUS, BOVINE). It is characterized by respiratory symptoms, increased oropharyngeal secretions and lacrimation, joint pains, tremor, and stiffness.

Also Known As:

Networked: 30 relevant articles (0 outcomes, 4 trials/studies)

Disease Context: Research Results

Related Diseases

1.	Infection
2.	Rabies (Hydrophobia)
3.	Parturient Paresis
4.	Paralysis (Palsy)
5.	Lumpy Skin Disease

Experts

1.	Walker, Peter J: 2 articles (02/2014 - 01/2008)
2.	Hunt, N: 1 article (12/2015)
3.	Hunt, R: 1 article (12/2015)
4.	Elliot, N: 1 article (12/2015)
5.	Walsh, S: 1 article (12/2015)
6.	Melville, L F: 1 article (12/2015)
7.	Barigye, R: 1 article (12/2015)
8.	Davis, S: 1 article (12/2015)
9.	Ting, Lu-Jen: 1 article (10/2014)
10.	Lee, Fan: 1 article (10/2014)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Ephemeral Fever:

1.	VaccinesIBA 09/01/1995 - "Field trials of ephemeral fever vaccines." 04/01/1973 - "Studies on vaccines against bovine ephemeral fever." 09/01/1995 - "Various bovine ephemeral fever (BEF) vaccines were tested between 1982 and 1984 in 24 Queensland herds; neutralising antibody responses were monitored and six of the herds were closely observed following natural challenge with ephemeral fever. " 12/01/1991 - "Vaccines are being developed for the cattle tick, Babesia, Anaplasma, sheep blowfly, buffalo fly and bovine ephemeral fever." 07/13/1985 - "Various vaccines containing the 919 strain of ephemeral fever virus were evaluated in experimental calves and in commercial cattle. "
2.	Complement System Proteins (Complement)IBA 01/01/1987 - "Preliminary studies of the complement fixation test to confirm the diagnosis of bovine ephemeral fever." 06/01/1983 - "Fluorescent antibody studies and complement fixation tests related the virus to bovine ephemeral fever (BEF) virus. "
3.	Glycoproteins (Glycoprotein)IBA 01/01/2008 - "Antigenic characterization of bovine ephemeral fever rhabdovirus G and GNS glycoproteins expressed from recombinant baculoviruses." 06/01/2006 - "DNA sequence analysis of glycoprotein G gene of bovine ephemeral fever virus and development of a double oil emulsion vaccine against bovine ephemeral fever." 11/01/1992 - "The genome of bovine ephemeral fever rhabdovirus contains two related glycoprotein genes." 01/01/1992 - "Glycoprotein-specific monoclonal antibodies (MAbs) were used to select escape mutants of bovine ephemeral fever (BEF) virus to determine the escape frequency for different epitopes and to construct an epitope map. "
4.	AntibodiesIBA 12/01/1998 - "No antibodies were detected in animals of herds which had no recorded clinical history of bovine ephemeral fever. " 01/01/1987 - "The CF antibodies to BEF virus were found to persist in 34 (89%) of 38 cattle which were bled 6 years after natural exposure to ephemeral fever. " 01/01/1987 - "CF antibodies were detected in all of 31 cattle after convalescence from experimental infection with BEF virus, in 208 (98%) of 213 cattle observed to have shown clinical ephemeral fever in an epidemic, in 96 cattle in these herds which did not show clinical signs of ephemeral fever and 16 cattle from herds in northern China outside the epidemic area. " 12/01/1990 - "These sera were tested for antibodies against foot-and-mouth disease, bovine herpes virus types 1 and 2, lumpy skin disease, bovine viral diarrhoea, Akabane, bovine ephemeral fever, bluetongue, enzootic bovine leucosis, African horse sickness and African swine fever viruses and Brucella abortus based on the expected species susceptibility. " 12/15/2015 - "Kinetics of pro-inflammatory cytokines, interleukin-10, and virus neutralising antibodies during acute ephemeral fever virus infections in Brahman cattle."
5.	EpitopesIBA 11/01/1998 - "Location of neutralizing epitopes on the G protein of bovine ephemeral fever rhabdovirus." 01/01/1992 - "Glycoprotein-specific monoclonal antibodies (MAbs) were used to select escape mutants of bovine ephemeral fever (BEF) virus to determine the escape frequency for different epitopes and to construct an epitope map. "
6.	Neutralizing AntibodiesIBA 10/10/2014 - "National and regional surveillance data indicated that 2 of the 3 major epizootics and 87% regional outbreaks were associated with lower neutralizing antibody titers and immunity coverage, reflecting the importance of population immunity for the control of bovine ephemeral fever. "
7.	Karyopherins (Importin)IBA 02/01/2014 - "Bovine ephemeral fever rhabdovirus α1 protein has viroporin-like properties and binds importin β1 and importin 7."
8.	Intergenic DNA (Junk DNA)IBA 06/01/1997 - "Genome organization and transcription strategy in the complex GNS-L intergenic region of bovine ephemeral fever rhabdovirus."
9.	GTP-Binding Proteins (G-Protein)IBA 11/01/1998 - "Location of neutralizing epitopes on the G protein of bovine ephemeral fever rhabdovirus."
10.	Interleukin-10 (Interleukin 10)IBA 12/15/2015 - "Kinetics of pro-inflammatory cytokines, interleukin-10, and virus neutralising antibodies during acute ephemeral fever virus infections in Brahman cattle."

Therapies and Procedures

1.	Intravenous Injections 07/01/1996 - "Ephemeral fever was induced by the intravenous injection of blood leucocyte layer from a clinical case. " 04/01/1985 - "Following intravenous injection of bovine ephemeral fever (BEF) virus 6 cattle were autopsied after clinical disease became evident. "
2.	Injections 06/01/1987 - "Antibody responses in cattle to 2 oil emulsion ephemeral fever vaccines were not satisfactory after a single injection, and severe local reactions were encountered when booster injections were applied."