Enteropeptidase

01/01/2015 - "In vitro experiments revealed enteropeptidase as a putative substrate for Bace1 suggesting a role in acute pancreatitis. "
04/01/1998 - "As expected, all rats induced with enterokinase and treated with saline died with hemorrhagic pancreatitis within 24 h. "
12/01/1995 - "GDOC caused mild pancreatitis, and pancreatic injury was aggravated when enterokinase was added. "
06/01/1994 - "Duodenopancreatic reflux of duodenal enterokinase may be important in the pathogenesis of experimental and clinical acute pancreatitis. "
01/01/1987 - "These findings show that enterokinase specifically increases the lethality of experimental bile salt pancreatitis and suggest that this bile-borne enzyme may in some cases pose a significant clinical threat."

12/01/2003 - "Expression of enteropeptidase in differentiated enterocytes, goblet cells, and the tumor cells in human duodenum."
02/20/1991 - "According to its aminoterminal amino acid sequence, a molecular mass of 28 kDa by SDS-PAGE, elution pattern in ion-exchange chromatography and ability to be activated by enteropeptidase, the zymogen is identical to that previously isolated from cyst fluid of ovarian tumors. "
06/01/1999 - "In the present study, expression of trypsin in various human cancer cell lines and tissues was studied by gelatin zymography and immunoblotting before and after enterokinase treatment and by immunohistochemistry. "

02/01/2011 - "In conclusion, this study describes the discovery of Pavlov's enterokinase in the human brain, a novel neuronal proteolytic pathway that gives rise to specific protein biomarkers (NfH(476-986) and Nf(H476-1026)) applicable to in vivo monitoring of diffuse axonal injury and neuronal loss in traumatic brain injury."

05/01/1989 - "Results of the studies of large intestine microflora, enterokinase and alkaline phosphatase activity in the feces of 298 children and adults suffering from trichocephaliasis are presented. "

12/01/1974 - "[Histochemical study on enterokinase in duodenal and jejunal biopsies of children with malabsorption syndromes]."