Subacute Bacterial Endocarditis

ENDOCARDIUM infection that is usually caused by STREPTOCOCCUS. Subacute infective endocarditis evolves over weeks and months with modest toxicity and rare metastatic infection.

Also Known As:

Endocarditis, Subacute Bacterial; Bacterial Endocarditides, Subacute; Bacterial Endocarditis, Subacute; Endocarditides, Subacute Bacterial; Subacute Bacterial Endocarditides; Endocarditis Lenta

Networked: 438 relevant articles (13 outcomes, 13 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1.	Glomerulonephritis
2.	Infections
3.	Endocarditis
4.	Congenital Heart Defects (Congenital Heart Defect)
5.	Systemic Lupus Erythematosus (Libman-Sacks Disease)

Experts

1.	Alves, Joana: 2 articles (07/2016 - 07/2016)
2.	Araújo, Maria Rita: 2 articles (07/2016 - 07/2016)
3.	Freitas, Sara: 2 articles (07/2016 - 07/2016)
4.	Marques, Céline: 2 articles (07/2016 - 07/2016)
5.	Santa-Bárbara, Rita: 2 articles (07/2016 - 07/2016)
6.	Xavier, Célia: 2 articles (07/2016 - 07/2016)
7.	Cunha, Burke A: 2 articles (01/2010 - 03/2003)
8.	Bromley, Kieran: 1 article (01/2022)
9.	Cherrington, Andrea: 1 article (01/2022)
10.	Foster, Nadine E: 1 article (01/2022)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Subacute Bacterial Endocarditis:

1.	Penicillins (Penicillin)FDA Link 05/01/1948 - "Subacute bacterial endocarditis; report of a case treated successfully with penicillin." 05/01/1946 - "Subacute bacterial endocarditis clinically cured with large doses of penicillin by continuous intramuscular drip." 04/01/1951 - "Subacute bacterial endocarditis; a review of 442 patients treated in 14 centers appointed by the Penicillin Trials Committee of the Medical Research Council." 12/29/1947 - "Penicillin in subacute bacterial endocarditis; report to the Medical Research Council on 147 cases treated at 14 centers designated by the Penicillin Trials Committee." 03/16/1946 - "Penicillin in subacute bacterial endocarditis; report to the Medical Research Council on 147 patients treated in 14 centres appointed by the Penicillin Clinical Trials Committee."
2.	Chlortetracycline (Aureomycin)FDA Link 01/12/1952 - "Treatment of subacute bacterial endocarditis with aureomycin." 05/01/1951 - "[Results of first cases of subacute bacterial endocarditis treated with aureomycin]." 03/01/1951 - "Subacute bacterial endocarditis successfully treated with aureomycin." 06/01/1950 - "[Brucellosis simulating endocarditis lenta cured by aureomycin]." 10/01/1953 - "Chlortetracycline (aureomycin) in prevention of bacteremia following oral surgery; attempt to prevent subacute bacterial endocarditis in patients with heart disease."
3.	Antigen-Antibody Complex (Immune Complex)IBA 06/01/1986 - "Secondary to subacute bacterial endocarditis was the presence of high levels of circulating immune complexes. " 08/01/1977 - "It is postulated that purpuric and other cutaneous lesions of subacute bacterial endocarditis are related to circulating immune complexes." 07/13/2017 - "Subacute bacterial endocarditis can have many different presentations; in rare instances, it can present as leukocytoclastic vasculitis owing to the effect of circulating immune complexes and micro-emboli on the vascular endothelium. " 01/01/2017 - "We report the case of a 57-year-old man who presented with subacute bacterial endocarditis secondary to Streptococcus mutans complicated by biopsy-proven immune complex-mediated glomerulonephritis (ICGN). " 01/01/1975 - "These observations suggest that the glomerular localization of very large, poorly soluble or insoluble immune complexes may be responsible for the focal glomerular changes seen in association with subacute bacterial endocarditis, with anaphylactoid purpura, or for some of the most severe lesions developing during chronic immune complex diseases."
4.	Anti-Bacterial Agents (Antibiotics)IBA 11/01/2004 - "The most recent recommendation for subacute bacterial endocarditis prophylactic antibiotic regimens is also described." 03/01/1977 - "Fourteen episodes of subacute bacterial endocarditis in 11 children were successfully treated with antibiotics, which in 13 cases were given largely by mouth. " 05/01/1976 - "Two years later the operation was repeated with the use of antibiotic cover, because the patient developed a paraprosthetic leak following subacute bacterial endocarditis with Staphylococcus aureus. " 04/01/1971 - "[Selection of antibiotics in the treatment of subacute bacterial endocarditis]." 10/01/1960 - "Isolation of a Corynebacterium and its transitional forms from a case of subacute bacterial endocarditis treated with antibiotics."
5.	Streptomycin (Streptomycin Sulfate)FDA Link 08/11/1951 - "[Endocarditis lenta and streptomycin]." 08/19/1950 - "Streptomycin in subacute bacterial endocarditis; report of 3 cases." 01/01/1950 - "Subacute bacterial endocarditis in a child, 10 months old, successfully treated with streptomycin." 11/03/1949 - "Streptomycin in the treatment of subacute bacterial endocarditis; review of the literature and report of a case caused by Bacteroides." 08/20/1949 - "The use of streptomycin in the treatment of subacute bacterial endocarditis; report of a case."
6.	Antineutrophil Cytoplasmic Antibodies (ANCA)IBA 01/01/2000 - "To report a potentially important limitation of antineutrophil cytoplasmic antibody (ANCA) testing: positive results in patients with subacute bacterial endocarditis (SBE). " 12/26/2012 - "Subacute bacterial endocarditis (SBE) occasionally exhibits positive cytoplasmic anti-neutrophil cytoplasmic antibody (c-ANCA) of the anti-proteinase-3 (PR-3) type. " 01/01/2012 - "Symptomatic anti-neutrophil cytoplasmic antibody-positive disease complicating subacute bacterial endocarditis: to treat or not to treat?" 12/14/2010 - "Seventeen cases of subacute bacterial endocarditis (SBE) associated with antineutrophil cytoplasmic antibody (ANCA) have been reported. " 12/14/2010 - "A case of mistaken identity: subacute bacterial endocarditis associated with p-antineutrophil cytoplasmic antibody."
7.	Erythromycin (Erycette)FDA LinkGeneric 12/31/1955 - "Subacute bacterial endocarditis treated by intravenously given erythromycin; report of a case." 09/03/1955 - "[The treatment of subacute bacterial endocarditis with erythromycin]." 01/21/1955 - "[Erythromycin therapy of subacute bacterial endocarditis]." 01/01/1955 - "[Osler's endocarditis lenta with Streptococci resistant to other antibiotics cured by erythromycin]." 10/01/1977 - "Erythromycin may be used as prophylactic therapy for subacute bacterial endocarditis and for recurrence of acute rheumatic fever in patients who are allergic to penicillin. "
8.	Tetracycline (Achromycin)FDA LinkGeneric 04/01/1955 - "[A case of subacute bacterial endocarditis cured with tetracycline]." 07/01/1954 - "[Tetracycline in the therapy of subacute bacterial endocarditis]." 01/01/1988 - "A combination of streptomycin, tetracycline and rifampicin with or without steroids was used successfully in neurobrucellosis, septicaemic shock and subacute bacterial endocarditis."
9.	Tumor Necrosis Factor Receptors (Tumor Necrosis Factor Receptor)IBA 12/01/1993 - "When patients with malaria were used as a control group of acute intravascular infection with high circulating TNF values, the ratio between soluble TNF receptors and TNF on admission was significantly greater in the patients with subacute bacterial endocarditis. " 12/01/1993 - "Circulating tumor necrosis factor alpha (TNF), soluble TNF receptors, and interleukin-6 in human subacute bacterial endocarditis."
10.	Prednisone (Sone)FDA LinkGeneric 06/01/1958 - "[A case of subacute bacterial endocarditis caused by staphylococcus treated with polyantibiotics and prednisone and cured with novobiocin]."

Therapies and Procedures

1.	Therapeutics 01/01/1949 - "Bacteriological studies on three morphologically and biochemically distinguishable streptococcal groups in endocarditis lenta; their importance for therapy." 11/19/1960 - "[Diagnosis and therapy of subacute bacterial endocarditis]." 03/30/1956 - "[Pathogen demonstration and choice of therapy in endocarditis lenta]." 01/01/1956 - "[Therapy and prognosis of subacute bacterial endocarditis]." 09/01/1953 - "[Diagnosis and therapy of subacute bacterial endocarditis]."
2.	Nursing Care 04/20/1983 - "Nursing care study: subacute bacterial endocarditis." 08/26/1981 - "Nursing care study: subacute bacterial endocarditis."
3.	Thrombolytic Therapy 08/01/1980 - "Fibrinolytic therapy in subacute bacterial endocarditis: an experimental study."
4.	Splenectomy 09/01/1962 - "Splenectomy in refractory subacute bacterial endocarditis." 05/27/1957 - "[Problem of splenectomy in endocarditis lenta, with report of a case]." 04/18/1952 - "[The place of splenectomy in the management of subacute bacterial endocarditis]." 04/06/1952 - "[Splenectomy in endocarditis lenta; new contributions to the therapy of endocarditis lenta]." 03/11/1960 - "[Successful splenectomy after repeated bacteremia after subacute bacterial endocarditis]."
5.	Antibiotic Prophylaxis 07/01/2016 - "Consider antibiotic prophylaxis for subacute bacterial endocarditis. " 07/01/2016 - "Consider antibiotic prophylaxis for subacute bacterial endocarditis. " 11/01/1982 - "To determine compliance with 1977 American Heart Association (AHA) recommendations for antibiotic prophylaxis (AbP) of subacute bacterial endocarditis (SBE), we mailed a questionnaire to 1019 licensed dentists from Dade County, Florida. " 11/01/1982 - "Antibiotic prophylaxis of subacute bacterial endocarditis for adult patients by dentists in Dade County, Florida." 01/01/2010 - "Viridans streptococcal (Streptococcus intermedius) mitral valve subacute bacterial endocarditis (SBE) in a patient with mitral valve prolapse after a dental procedure: the importance of antibiotic prophylaxis."