Endarterectomy (Thromboendarterectomy)

Surgical excision, performed under general anesthesia, of the atheromatous tunica intima of an artery. When reconstruction of an artery is performed as an endovascular procedure through a catheter, it is called ATHERECTOMY.

Also Known As:

Networked: 3494 relevant articles (222 outcomes, 478 trials/studies)

Relationship Network

Therapy Context: Research Results

Experts

1.	Brott, Thomas G: 42 articles (01/2022 - 07/2001)
2.	Brown, Martin M: 41 articles (01/2022 - 01/2004)
3.	Mayer, Eckhard: 36 articles (01/2022 - 03/2002)
4.	Bonati, Leo H: 35 articles (01/2022 - 10/2008)
5.	Howard, George: 27 articles (01/2022 - 07/2001)
6.	Pepke-Zaba, Joanna: 26 articles (07/2021 - 06/2004)
7.	Auger, William R: 26 articles (01/2021 - 09/2004)
8.	Jenkins, David P: 22 articles (03/2022 - 07/2007)
9.	de Perrot, Marc: 21 articles (03/2022 - 09/2007)
10.	Fadel, Elie: 21 articles (01/2022 - 04/2007)

Related Diseases

1.	Pulmonary Hypertension 04/21/2022 - "Pulmonary endarterectomy (PEA) is one of the most effective treatments for chronic thromboembolic pulmonary hypertension (CTEPH). " 01/01/2022 - "However, CTEPH has a highly significant feature that distinguishes it from other forms of pulmonary hypertension: the fact that it can be cured through treatment with pulmonary thromboendarterectomy. " 01/01/2018 - "Pulmonary endarterectomy is the gold standard treatment for chronic thromboembolic pulmonary hypertension and provides immediate correction of hemodynamic parameters in most patients. " 12/01/2011 - "Pulmonary endarterectomy (PEA) is the most effective treatment for chronic thromboembolic pulmonary hypertension (CTEPH). " 02/01/2008 - "Pulmonary endarterectomy is the best treatment for patients with chronic thromboembolic pulmonary hypertension. "
2.	Carotid Stenosis (Carotid Artery Stenosis) 07/01/2018 - "It remains unclear whether carotid artery stenting (CAS) or endarterectomy (CEA) is the best treatment strategy for radiation-induced carotid artery stenosis. " 01/01/1997 - "These results encourage the feasibility of prognostic studies to evaluate the clinical significance of embolic signals and suggest that silent microembolism could be helpful in selecting a high-risk group of asymptomatic or < 70% carotid stenoses for endarterectomy." 01/26/1995 - "Current trials are addressing the question of whether endarterectomy is beneficial for patients with moderate degrees of carotid stenosis. " 09/01/2005 - "Protected stenting has emerged as a safe and effective alternative to endarterectomy for the treatment of carotid stenosis in patients at high operative risk. " 02/01/1996 - "The reported risks of endarterectomy for symptomatic carotid stenosis show significantly greater variability than would be expected by chance. "
3.	Stroke (Strokes) 09/01/2012 - "For symptomatic patients, surgery remains the best option, since stenting is associated with a 61% relative risk increase of periprocedural stroke or death compared to endarterectomy. " 12/01/2011 - "High stroke event rates among carotid artery stenting (CAS)-treated patients in the Carotid Revascularization Endarterectomy Versus Stenting Trial (CREST) lead-in registry generated an a priori hypothesis that age may modify the relative efficacy of CAS versus carotid endarterectomy (CEA). " 06/19/1999 - "We investigated whether the efficacy of endarterectomy would be improved if patients with a high risk of stroke on medical treatment and a low risk of operative stroke or death could be identified. " 01/01/2020 - "Beyond the periprocedural period, carotid stenting is as effective in preventing recurrent stroke as endarterectomy. " 12/01/2022 - "The SCAIL score improved the identification of early recurrent stroke in subgroups who did not experience benefit in endarterectomy trials. "
4.	Pathologic Constriction (Stenosis) 12/01/2020 - "Endarterectomy might be of some benefit for participants with 50% to 69% symptomatic stenosis (moderate-quality evidence) and highly beneficial for those with 70% to 99% stenosis (moderate-quality evidence)." 01/01/2017 - "Endarterectomy was of some benefit for participants with 50% to 69% symptomatic stenosis (moderate-quality evidence), and highly beneficial for those with 70% to 99% stenosis without near-occlusion (moderate-quality evidence). " 04/13/2011 - "Endarterectomy is of some benefit for 50% to 69% symptomatic stenosis and highly beneficial for 70% to 99% stenosis without near-occlusion. " 09/01/2005 - "Two large trials indicated that endarterectomy was less beneficial for symptomatic patients with internal carotid artery (ICA) near occlusion than for patients who had severe stenosis without near occlusion. " 11/01/1999 - "The efficacy of endarterectomy for patients with symptomatic high-grade stenosis of the extracranial carotid artery has been firmly established. "
5.	Pulmonary Embolism 01/01/2001 - "The median sternotomy approach for the treatment of chronic pulmonary thromboembolism was recently improved by Daily, Jamieson, and coworkers who adopted it for use under cardiopulmonary bypass with intermittent circulatory arrest; however, we have sometimes found that the circulatory arrest time was too short to complete thromboendarterectomy. " 08/01/2003 - "This case suggests that pulmonary thromboendarterectomy may be beneficial for patients with subacute pulmonary thromboembolism." 09/01/2005 - "Thromboendarterectomy is an effective treatment for chronic pulmonary thromboembolism. " 03/15/2005 - "Pulmonary thromboendarterectomy is an effective treatment for chronic pulmonary thromboembolism. " 07/01/2000 - "Immediately after pulmonary thromboendarterectomy for chronic pulmonary thromboembolism, NO inhalation improved oxygenation; at 12 h after surgery, NO inhalation resulted in decreased pulmonary vascular resistance, although both changes were small."

Related Drugs and Biologics

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3.	Homocysteine
4.	Soluble Guanylyl Cyclase
5.	Aspirin (Acetylsalicylic Acid)
6.	Epoprostenol (Prostacyclin)
7.	Fibrinogen (Factor I)
8.	Monoclonal Antibodies
9.	Platelet Aggregation Inhibitors (Antiplatelet Drugs)
10.	Retinaldehyde (Retinal)

Related Therapies and Procedures

1.	Therapeutics
2.	Carotid Endarterectomy
3.	Stents
4.	Coronary Artery Bypass (Coronary Artery Bypass Surgery)
5.	Cardiopulmonary Bypass (Heart-Lung Bypass)