Encephalomyelitis (Myeloencephalitis)

A general term indicating inflammation of the BRAIN and SPINAL CORD, often used to indicate an infectious process, but also applicable to a variety of autoimmune and toxic-metabolic conditions. There is significant overlap regarding the usage of this term and ENCEPHALITIS in the literature.
Also Known As:
Myeloencephalitis; Encephalomyelitis, Inflammatory; Inflammatory Encephalomyelitis; Myeloencephalitides
Networked: 862 relevant articles (55 outcomes, 63 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Multiple Sclerosis
2. Arthritis (Polyarthritis)
3. Inflammation
4. Autoimmune Diseases (Autoimmune Disease)
5. Demyelinating Diseases (Demyelinating Disease)


1. Lassmann, Hans: 10 articles (12/2015 - 07/2003)
2. Griffin, Diane E: 8 articles (08/2015 - 06/2003)
3. Bergmann, Cornelia C: 7 articles (01/2015 - 03/2008)
4. Stohlman, Stephen A: 7 articles (01/2015 - 03/2008)
5. Vincent, Angela: 7 articles (08/2014 - 12/2011)
6. Steinman, Lawrence: 6 articles (01/2015 - 09/2003)
7. Baumgärtner, Wolfgang: 6 articles (01/2015 - 08/2006)
8. Furr, M: 6 articles (09/2013 - 01/2000)
9. Matsumoto, Yoh: 6 articles (08/2011 - 05/2002)
10. Shin, T: 6 articles (12/2001 - 06/2000)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Encephalomyelitis:
1. PeptidesIBA
2. VaccinesIBA
3. Intravenous Immunoglobulins (IVIG)FDA Link
4. AntibodiesIBA
5. Amyloid (Amyloid Fibrils)IBA
6. Viral RNAIBA
7. toltrazurilIBA
8. Adrenal Cortex Hormones (Corticosteroids)IBA
01/01/2012 - "Nevertheless, TPE is currently used in severe acute forms of demyelinating disease (multiple sclerosis/acute encephalomyelitis) unresponsive to corticosteroids. "
12/01/1991 - "The immunomodulatory action of corticosteroids and the ability of central noradrenergic systems to activate the hypothalamic-pituitary-adrenal (HPA) axis led us to investigate the relationship between neuroendocrine status and the clinical course of encephalomyelitis (EAE) following adrenalectomy and depletion of noradrenaline (NA) centrally or peripherally. "
04/15/2013 - "Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS) has been described as a clinically and radiologically distinct pontine-predominant encephalomyelitis with a favorable response to high dose corticosteroids and usually requiring chronic immunosuppresive therapy. "
02/01/2010 - "The efficacy of high-dose corticosteroids, plasmapheresis, and intravenous immunoglobulins have been studied extensively in GBS, myasthenia gravis, and demyelinating disorders such as multiple sclerosis and acute demyelinating encephalomyelitis. "
01/01/2015 - "The efficacy of IVIG in children has been shown as first line treatment in Guillain-Barre syndrome, chronic inflammatory demyelinating polyneuropathy, multifocal motor neuropathy, dermatomyositis as a second-line drug in the combination with prednisolone or immunosuppressors in patients refractory to treatment with corticosteroids and cytostatics, myasthenic crisis in myasthenia gravis, exacerbations and short-term treatment of severe forms, non-responsiveness to acetylcholinesterase inhibitors, multiple sclerosis as second or third line of treatment in patients with relapsing-remitting course with intolerance to standard immunomodulatory therapy, acute multiple encephalomyelitis with no response to the treatment with high doses of corticosteroids, paraneoplastic syndromes, pharmacoresistant epilepsy and autoimmune encephalitis. "
9. 1- (2- (1- adamantyl)ethyl)- 1- pentyl- 3- (3- (4- pyridyl)propyl)ureaIBA
10. Proteins (Proteins, Gene)IBA

Therapies and Procedures

1. Thymectomy
2. Immunotherapy
3. Oral Administration
4. Plasmapheresis
5. Immunomodulation