Emulsions

Colloids formed by the combination of two immiscible liquids such as oil and water. Lipid-in-water emulsions are usually liquid, like milk or lotion. Water-in-lipid emulsions tend to be creams. The formation of emulsions may be aided by amphiphatic molecules that surround one component of the system to form MICELLES.

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Networked: 4178 relevant articles (394 outcomes, 652 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Puder, Mark: 32 articles (01/2022 - 03/2008)
2.	Gura, Kathleen M: 29 articles (01/2022 - 03/2008)
3.	Mayer, Konstantin: 19 articles (06/2020 - 05/2002)
4.	Maranhão, Raul C: 18 articles (03/2014 - 04/2002)
5.	Sohn, Ju-Tae: 15 articles (01/2022 - 02/2016)
6.	Baudouin, Christophe: 13 articles (06/2022 - 08/2009)
7.	Reed, Steven G: 13 articles (10/2019 - 05/2009)
8.	Garrigue, Jean-Sébastien: 12 articles (01/2021 - 10/2012)
9.	Amrane, Mourad: 11 articles (07/2020 - 06/2016)
10.	Ismail, Dahlia: 11 articles (07/2020 - 06/2016)

Related Diseases

1.	Neoplasms (Cancer) 02/01/2023 - "HLA-I transgenic mice administered DSP-7888 Emulsion plus anti-PD-1 experienced significantly greater reductions in tumor size than mice treated with either agent alone. " 01/01/2023 - "Treatment with PSO nano-emulsions caused a significant reduction in the tumor size and weight, in a dose dependent manner, compared to tumor control group. " 03/01/1982 - "In the SC-SC system at the dose of 0.2 mg/kg or 1.0 mg/kg, the mice administered with the emulsion ADM (emulsion ADM group) showed prolonged survival time and stronger inhibitory effect of the tumor growth than free ADM group, and at 1.0 mg/kg, showed statistically significant different inhibition of the tumor growth from free ADM group. " 08/01/1981 - "Immunization of guinea pigs with a mixture of irradiated syngeneic tumor cells plus mycobacterial cell walls in an oil-in-water emulsion eradicated tumor cells remaining in lymph nodes after limited surgery for stage II experimental cancer and prevented progression of the disease to stage III. Tumor intravenously implanted in the lungs of animals after limited surgery for stage II disease was also eliminated by immunization." 02/10/2023 - "In this study, we aimed to develop a mitochondria-targeting emulsion, using DQA and α-TOS (DTOS), for cancer treatment. "
2.	Dry Eye Syndromes (Dry Eye Syndrome) 11/01/2012 - "Cationic emulsions (CEs), developed as vehicles for lipophilic drugs, have been shown to be safe and effective for the treatment of dry eye. " 12/01/2008 - "CsA emulsion is approved by the FDA for the treatment of dry eye, while clinical trials of this agent have demonstrated efficacy and safety of CsA. " 01/01/2015 - "A single-center, open-label study consisting of two visits over the course of approximately 2 weeks was conducted to evaluate the efficacy of Retaine™ ophthalmic emulsion in improving the signs and symptoms of dry eye. " 10/01/2014 - "Ocular tolerability and efficacy of a cationic emulsion in patients with mild to moderate dry eye disease - a randomised comparative study." 11/04/2016 - "Efficacy and safety of a cationic emulsion in the treatment of moderate to severe dry eye disease: a randomized controlled study."
3.	Infections 10/03/2021 - "This study demonstrated the impacts of oil-in-water emulsion adjuvant on sRSV vaccination and the potential roles of NK and NKT cells in protection and respiratory disease after adjuvanted RSV vaccination and infection in a mouse model." 03/01/2009 - "This study suggests that polyacrylate nanoparticle-containing emulsions may afford promising opportunities for treating both skin and systemic infections." 12/01/2022 - "The primary outcome included total and categorical CR-BSI rates expressed as the average with standard error (SE) number of infections per 1000 fat emulsion days. " 10/03/2021 - "Natural killer cells contribute to enhanced respiratory disease after oil-in-water emulsion adjuvanted vaccination against respiratory syncytial virus and infection." 06/23/2021 - "Results suggest that a Pickering emulsion is able to improve physical interactions between the conidia and their surroundings, while weakening the host through a plethora of mechanisms, increasing the chance of an acute infection."
4.	Inflammation (Inflammations) 03/01/2018 - "Oxidative stress and inflammation which were increased significantly in CCl4 control group showed improvement on administration of the three different oil emulsions. " 12/01/2021 - "The present study aimed to compare the efficacy of 0.1% CsA CE with that of 0.05% CsA emulsion for ocular surface damage and inflammation in the cases of murine DE with different severities. " 09/05/2022 - "Few studies have focused on the role and mechanism of emulsions in inflammation relief. " 02/01/2021 - "Therefore, this study evaluated the effect of a nano-emulsion based on this herbal derivative (NCS) against VBm-induced inflammation in Wistar rats. " 06/30/2023 - "Pathological tissue sections showed that inflammatory cells in the epidermis, dermis, and basal layer were significantly reduced, and the granulation tissue was proliferated in the inflammation-targeted emulsion gel group and the non-targeted emulsion gel group. "
5.	Hepatocellular Carcinoma (Hepatoma) 01/01/2018 - "To compare the stability of stable and unstable water-in-oil emulsions and the efficacy and safety of these emulsions in a single-center, prospective double-blind trial of transarterial chemoembolization for hepatocellular carcinoma (HCC). " 09/01/2012 - "The purpose of this study was to evaluate the safety and effectiveness of ultraselective TAI (UTI) of a W/O/W emulsion for hepatocellular carcinoma (HCC). " 08/01/2011 - "The purpose of this study was to evaluate the safety and effectiveness of transcatheter arterial infusion (TAI) of W/O/W emulsion via a cystic artery for hepatocellular carcinoma (HCC). " 11/01/2007 - "This study was to retrospectively compare the effectiveness of transarterial embolization (TAE) using a lipidol emulsion for large lesion of hepatocellular carcinoma (HCC). " 01/01/2023 - "STATEMENT OF SIGNIFICANCE: Conventional transarterial chemoembolization (TACE) formulations are rapidly dissociated due to the instability of the emulsion, resulting in insufficient local drug concentrations in hepatocellular carcinoma (HCC). "

Related Drugs and Biologics

1.	Lipids
2.	Cyclosporine (Ciclosporin)
3.	Vaccines
4.	Fish Oils
5.	Ethiodized Oil (Ethiodol)
6.	Oxygen (Dioxygen)
7.	Triglycerides (Triacylglycerol)
8.	Fluorocarbons
9.	Solvents
10.	Emulsions

Related Therapies and Procedures

1.	Therapeutics
2.	Drug Therapy (Chemotherapy)
3.	Parenteral Nutrition
4.	Injections
5.	Resuscitation