Empyema

01/01/1999 - "Treatment with antibiotics and drainage of empyema resulted in a good outcome in the majority of cases."
04/01/1992 - "Early intrapleural drainage and appropriate antibiotics should be the mainstay of treatment for empyema for the majority of children in Zimbabwe."
12/01/2003 - "Continuous soft tube drainage with intrapleural fibrinolysis and antibiotics is a safe treatment for postpneumonectomy empyema in patients who are not appropriate candidates for operative management."
11/01/2002 - "Gemella empyema cured without antibiotics: a case report."
11/01/1999 - "Thoracic drainage, lavage and systemic administration of antibiotics improved his empyema. "

03/01/2012 - "Is streptokinase fibrinolysis the best treatment for empyema in pediatric patients? "
12/01/2018 - "Intrapleural streptokinase was effective for multi-loculated empyema even when it was administered more than 14 days after disease onset and four to six doses were superior to three doses."
12/01/2018 - "Intrapleural streptokinase is effective and safe for children with multi-loculated empyema regardless of the time from disease onset."
10/01/2003 - "Intrapleural Streptokinase is a safe and effective means of increasing the tube drainage in multiloculated Empyema without causing systemic fibrinolysis."
12/01/2018 - "This study compared the efficacy of administering intrapleural streptokinase to children with multi-loculated empyema within 14 days or at any time after disease onset. "

12/01/2001 - "We conclude that intrapleural instillation of urokinase in the management of parapneumonic empyema provides a better outcome and reduces the need for decortication."
05/01/2015 - "Urokinase and VATS are equally effective for septated empyema."
01/01/2019 - "Phase 1 trial of intrapleural LTI-01; single chain urokinase in complicated parapneumonic effusions or empyema."
04/01/2002 - "A randomised double blind placebo controlled trial of intrapleural urokinase was performed in children with parapneumonic empyema. "
04/01/2002 - "Randomised trial of intrapleural urokinase in the treatment of childhood empyema."

05/01/2012 - "Intrapleural instillation of Alteplase is significantly more effective than Placebo in patients with empyema and PPE (95% vs.12%). "
03/01/2015 - "Large-dose intrapleural alteplase is effective in facilitating pleural drainage in pediatric patients with complicated parapneumonic effusion or empyema. "
05/01/2012 - "A double blind randomized cross over trial to compare the rate of decortication, safety and efficacy of intrapleural instillation of Alteplase vs. Placebo in empyema and complicated parapneumonic effusions (CPE). "
03/01/2003 - "Controlled trials need to be conducted to investigate fully the efficacy, dosing, and safety of intrapleural alteplase in the treatment of patients with CPE and empyema."
01/01/2018 - "Patients, who received TT were more likely than non-TT patients to receive tissue plasminogen activator, develop an empyema, have fewer hospital-free days, and are discharged to rehabilitation rather than home. "

06/01/1999 - "Intrapleural instillation of fibrinolytic agents has been shown, in a number of studies, to be an effective and safe mode of treatment in complicated parapneumonic effusions and empyema, minimizing the need for surgical intervention. "
10/01/2010 - "The aim of the study is to systematically evaluate data from randomized controlled trials (RCTs) on the efficacy of using intrapleural fibrinolytic agents in the treatment of complicated parapneumonic effusions or empyema in children. "
06/01/2023 - "MEDLINE and EMBASE were searched through April 2022 to identify randomized controlled trials (RCTs) that investigated outcomes in patients with complicated parapneumonic effusion or empyema who were treated with intrapleural fibrinolytic agents. "
09/01/2007 - "Further studies with better research design to compare the fibrinolytic agent instillation and the VATS as the first step treatment of childhood empyema are needed."
03/01/2006 - "We performed a meta-analysis of all properly randomized trials comparing intrapleural fibrinolytic agents with placebo in adult patients with empyema and complicated parapneumonic effusions. "

10/01/2023 - "A total of 38 patients were found to have been treated with concurrent tPA and DNase for complicated parapneumonic effusion or empyema. "
04/01/2022 - "Although the use of t-PA and DNase has been well studied in the context of empyema, the literature is limited in regards to the use of these medications in MPEs. "
01/01/2022 - "DNase inhibits early biofilm formation in Pseudomonas aeruginosa- or Staphylococcus aureus-induced empyema models."
10/01/2020 - "Bronchopleural communication following intrapleural doses of tPA/DNase for empyema."
01/01/2018 - "Resolution of CPE/empyema with intrapleural tPA/DNase was achieved in two-thirds of the patients (n = 57). "

10/01/2010 - "There is little evidence that intrapleural fibrinolysis is more effective than normal saline in the local treatment of complicated parapneumonic effusions or empyema in children. "
02/01/2021 - "In (I+) group, the slow-flow irrigation drainage tube was placed along the primary pleural drainage tube into the empyema cavity, irrigated with normal saline. "
04/01/2007 - "After an empyema was verified by pleural fluid analysis at 24 h, SH 3 ml (30 mg) was introduced into the right pleural cavity in the treatment group, but normal saline 3 ml was used in the control group. "
06/01/2006 - "The aim of this study was to determine if tPA or rhDNase, or a combination of the two, is more effective than saline solution in the treatment of empyema in rabbits. "
01/30/1999 - "Simple parapneumonic effusions are managed by drainage with or without rinsing with normal saline, while in advanced empyema, instillations with fibrinolytic agents have proved safe and effective. "

07/27/1946 - "Gram-negative bacillus empyema cured by intrapleural penicillin."
05/31/1946 - "Prophylactic and curative value of penicillin in empyema following pulmonary exeresis; a study of 203 cases."
01/01/2003 - "Culture-negative childhood empyema is usually due to penicillin-sensitive Streptococcus pneumoniae capsular serotype 1."
03/01/2001 - "Outcome of children treated with penicillin and derivatives was good, including children with empyema and pneumatocele and two patients with penicillin-resistant S. "
03/01/1993 - "[Empyema caused by Pasteurella multocida resistant to penicillin]."

01/01/2017 - "A randomized controlled trial of adults with empyema recently demonstrated decreased length of stay in hospital in patients treated with intrapleurally administered dornase alfa and fibrinolytics compared to fibrinolytics alone. "
06/01/2006 - "The aim of this study was to determine if tPA or rhDNase, or a combination of the two, is more effective than saline solution in the treatment of empyema in rabbits. "
06/01/2006 - "The combination of alteplase and rhDNase is more effective in the treatment of rabbit empyema than either agent alone. "
06/01/2021 - "Intrapleural combination of tissue plasminogen activator and dornase alfa is a promising treatment for empyema in adults. "
06/01/2021 - "The intrapleural treatment of dornase alfa and tissue plasminogen activator as treatment of empyema was safe in ten children with empyema. "

09/01/1996 - "Bilateral empyema and pneumonia due to chloramphenicol-resistant Haemophilus influenzae type b."
12/01/1956 - "Bronchopneumonia, empyema, pneumothorax and bacteremia due to Salmonella choleraesuis (var. Kunzendorf) treated with chloramphenicol."
04/01/2012 - "suppuration: empyema and multiple abscesses were treated successfully with the combination of amikacin and chloramphenicol with good progression in the short and medium terms. "
01/01/2002 - "The aim of this study was to evaluate the efficacy of cefuroxime, compared with the combination of dicloxacillin/chloramphenicol, for the treatment of children with parapneumonic pleural effusion or empyema. "
01/01/2002 - "Forty patients, aged 3 months to 5 years, with pleural effusion or empyema were randomized to receive cefuroxime (100 mg/kg/day) IV (n=20) or chloramphenicol (100 mg/kg/day) plus dicloxacillin (200 mg/kg/day) IV (n=20). "

01/01/2004 - "On the basis of the study results and the literature review the authors conclude that the applied therapy yields good results in the treatment of postpulmonectomy empyema."
05/12/2022 - "We present the first reported case of empyema necessitans caused by Mycobacterium xenopi, which was treated successfully with antimycobacterial therapy. "
10/09/2020 - "Two patients diagnosed with BPF with empyema were selected to undergo surgery in our hospital because they could not be cured by conservative and endoscopic therapy for 1 or more years. "
10/09/2020 - "Thus, pedicled latissimus dorsi muscle flap transfer associated with conservative and endoscopic therapies for BPF with empyema is a useful treatment option, offering feasible and efficient management with promising results."
06/01/2004 - "Despite continued improvement in medical therapy, pediatric empyema remains a challenging problem for the surgeon. "

01/01/2006 - "Conversion thoracotomy should be liberally used if a chronic stage III empyema is found at VATS exploration since open decortication is still the best treatment modality for chronic empyema. "
01/01/2023 - "Open thoracotomy still plays an important role in the management of delayed and complicated cases of empyema and has always produced good results. "
10/01/1982 - "Early open thoracotomy to eliminate the empyema with decortication of the fibrinous peel and reexpansion of the lung has proven safe and effective for 25 years. "
01/01/2020 - "Decortication and pleurectomy via a posterolateral thoracotomy resulted in significant clinico-functional improvement in patients with chronic empyema, regardless of the bacteriology, side of occurrence of the lesion, smoking habit, or diabetic status of the patient."
01/01/2012 - "Thoracotomy and decortication in children with empyema can be safely done in Cameroon using a simple drainage system with good results compared to those in the literature."

09/01/2012 - "Therapeutic drainage with small-bore tube thoracostomy has been shown to be a safe and effective treatment of early stage empyema. "
01/01/2016 - "OPEN WINDOW THORACOSTOMY, STILL AN OPTION IN THE MANAGEMENT OF CHRONIC EMPYEMA: EXPERIENCE FROM AYDER REFERRAL HOSPITAL."
05/01/2006 - "Empyema was treated with tube thoracostomy, and full remission was observed after 33 d. "
02/01/1997 - "The Clagett open-window thoracostomy is performed to give patients with empyema improved quality of life and other outcomes. "
01/01/2012 - "The aim of this study was to review our experience with tube thoracostomy in the management of empyema thoracis in children. "

03/01/1991 - "As a sequel to a paper reporting good results obtained in 12 patients with empyema thoracis treated by thoracoscopic debridement and irrigation in our department, subsequent experience with a further 18 patients is reported. "
12/01/2003 - "This study analyzed whether video-assisted thoracoscopic debridement (VATD) as first-line treatment is effective in the management of pediatric parapneumonic empyema. "
01/01/2012 - "VATS debridement and decortication is safe and effective treatment in the management of stage II and stage III empyema thoracis."
10/01/2007 - "In fibrinopurulent empyema, VATS debridement is safe and effective, with minimal morbidity and no deaths. "
08/01/1995 - "Recently, Kern and Rodgers introduced thoracoscopic debridement as an adjunct to the management of children with empyema, with promising results. "

09/01/2008 - "-assisted thoracoscopy surgery was performed following failure of the prescribed antifungal treatment and chest tube drainage, and the empyema resolved completely 3 months postoperatively,with no evidence of recurrence after 5 months' follow-up."
06/01/1997 - "This study supports previous expert opinion statements and conclusions from retrospective analyses that early chest tube placement (relative to delayed chest tube placement) is beneficial for the treatment of empyema."
01/01/2018 - "Chest tube drainage with fibrinolytics is a cost-effective treatment option for parapneumonic effusion and empyema in children. "
12/01/1999 - "To determine if therapeutic thoracentesis is as effective as early chest tube placement or no drainage procedure in the treatment of early empyema in rabbits. "
11/01/2020 - "We wanted to compare efficacy of Thopaz™ with our conventional intercostal chest tube drain in patients undergoing decortications for empyema thoracis. "