Ellagic Acid

A fused four ring compound occurring free or combined in galls. Isolated from the kino of Eucalyptus maculata Hook and E. Hemipholia F. Muell. Activates Factor XII of the blood clotting system which also causes kinin release; used in research and as a dye.

Also Known As:

Networked: 702 relevant articles (70 outcomes, 174 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Tomás-Barberán, Francisco A: 11 articles (03/2017 - 01/2005)
2.	Sarkaki, Alireza: 10 articles (05/2020 - 01/2015)
3.	González-Sarrías, Antonio: 10 articles (03/2017 - 06/2009)
4.	Espín, Juan Carlos: 9 articles (03/2017 - 01/2005)
5.	Dianat, Mahin: 7 articles (06/2020 - 03/2015)
6.	Farbood, Yaghoub: 7 articles (01/2019 - 05/2013)
7.	Naghizadeh, Bahareh: 6 articles (10/2016 - 05/2013)
8.	Badavi, Mohammad: 5 articles (06/2020 - 03/2015)
9.	Farbood, Yaghoob: 5 articles (05/2020 - 01/2015)
10.	Khodadadi, Ali: 5 articles (04/2017 - 01/2015)

Related Diseases

1.	Carcinogenesis 05/28/1993 - "The aims of this study were to define the cumulative exposure of Canadian smokers to NNK and to characterize the efficacy of ellagic acid to inhibit lung tumorigenesis induced by NNK. " 03/15/1984 - "Protection against 3-methylcholanthrene-induced skin tumorigenesis in Balb/C mice by ellagic acid." 02/01/2001 - "Although ellagic acid, an abundant component in these berries, has been shown to inhibit carcinogenesis both in vivo and in vitro, several studies have reported that other compounds in the berries may also contribute to the observed inhibitory effect. " 01/01/2017 - "Beneficial influence of ellagic acid on biochemical indexes associated with experimentally induced colon carcinogenesis." 10/15/2008 - "The content of ellagic acid (EA), a naturally occurring inhibitor of carcinogenesis, was determined in chestnut fruits and bark. "
2.	Neoplasms (Cancer) 09/01/2023 - "At present, the analysis of the anti-tumor mechanism of ellagic acid is slightly lacking, so this study comprehensively searched the literature on the anti-tumor mechanism of ellagic acid in various databases, reviewed the research progress of the anti-tumor effect and mechanism of ellagic acid, in order to provide reference and theoretical basis for the further development and application of ellagic acid." 02/01/2021 - "Ellagic acid and human cancers: a systems pharmacology and docking study to identify principal hub genes and main mechanisms of action." 04/01/2020 - "Antiinflammatory and anti-cancer activities of pomegranate and its constituent, ellagic acid: Evidence from cellular, animal, and clinical studies." 02/01/2014 - "The objective of the present study was to evaluate the sensitivity to and possible apoptosis mechanism induced by ellagic acid in neuronal tumor cells. " 01/01/2013 - "This study is the first to show that, in addition to being considered a possible agent for preventing tumor growth, ellagic acid possesses potent antiplatelet properties. "
3.	Inflammation (Inflammations) 08/01/2010 - "Therefore, dietary and pharmacological interventions with berries rich in ellagic acid may be promising treatment strategies interrupting skin wrinkle and inflammation associated with chronic UV exposure leading to photoageing." 11/01/2022 - "Ellagic Acid may reduce oxidative stress level and prevent induction of inflammation and cell death against hepatic IR." 01/01/2022 - "Dietary supplementation ellagic acid on the growth, intestinal immune response, microbiota, and inflammation in weaned piglets." 01/01/2020 - "Ellagic acid protects Caco-2 cell monolayers against inflammation-induced permeabilization." 01/01/2020 - "Ellagic Acid Prevents Oxidative Stress, Inflammation, and Histopathological Alterations in Acrylamide-Induced Hepatotoxicity in Wistar Rats."
4.	Infections 12/01/2018 - "In Vivo Efficacy of Ellagic Acid against Candida albicans in a Drosophila melanogaster Infection Model." 01/01/2019 - "We used an infection model to evaluate the anticryptosporidial activity of ellagic acid (EA), an NDK inhibitor. " 03/01/2018 - "We conclude that ellagic acid can inhibit HIV-1 infection without cytotoxicity. " 03/01/2018 - "Anti-HIV-1NPO3 activity of ellagic acid was investigated at a multiplicity of infection (MOI) of 0.01. " 01/01/2018 - "Antimicrobial activity of ellagic acid against Helicobacter pylori isolates from India and during infections in mice."
5.	Reperfusion Injury 01/01/2012 - "We aimed to investigate the possible protective effects of ellagic acid (EA) on the liver and remote organs against the hepatic ischemia-reperfusion injury. " 02/01/2020 - "Ellagic Acid Ameliorates Renal Ischemic-Reperfusion Injury Through NOX4/JAK/STAT Signaling Pathway." 11/01/2022 - "Ellagic Acid Alleviates Mice Intestinal Ischemia-Reperfusion Injury: A Study Based on Transcriptomics Combined with Functional Experiments." 06/18/2022 - "Ellagic acid Alleviates hepatic ischemia-reperfusion injury in C57 mice via the Caspase-1-GSDMD pathway." 01/01/2012 - "In our experiments ellagic acid reduced the liver oxidative stress induced by ischemia-reperfusion injury. "

Related Drugs and Biologics

1.	Antioxidants
2.	Resveratrol
3.	Cisplatin (Platino)
4.	Polyphenols
5.	Quercetin
6.	Phytochemicals
7.	Flavonoids
8.	DNA (Deoxyribonucleic Acid)
9.	Phenol (Carbolic Acid)
10.	Estrogens (Estrogen)

Related Therapies and Procedures

1.	Aftercare (After-Treatment)
2.	Therapeutics
3.	Microspheres (Microsphere)
4.	Drug Therapy (Chemotherapy)
5.	Chemoprevention