Paroxysmal Dyspnea

A disorder characterized by sudden attacks of respiratory distress in at rest patients with HEART FAILURE and PULMONARY EDEMA. It usually occurs at night after several hours of sleep in a reclining position. Patients awaken with a feeling of suffocation, coughing, a cold sweat, and TACHYCARDIA. When there is significant WHEEZING, it is called cardiac asthma.

Also Known As:

Networked: 15 relevant articles (1 outcomes, 1 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1.	Asthma (Bronchial Asthma)
2.	Respiratory Sounds (Crackle)
3.	Cough
4.	Renal Insufficiency (Renal Failure)
5.	Stroke (Strokes)

Experts

1.	Schulman, Peter: 1 article (01/2012)
2.	Bockorny, Bruno: 1 article (01/2012)
3.	Bona, Robert: 1 article (01/2012)
4.	Bockorny, Margarita: 1 article (01/2012)
5.	Chakravarty, Saneka: 1 article (01/2012)
6.	Levin, Regina A: 1 article (02/2010)
7.	Gartner, James A: 1 article (02/2010)
8.	Chen, Song: 1 article (02/2010)
9.	Schulz, Henk: 1 article (01/2009)
10.	Karimi-Nejad, Yasmin: 1 article (01/2009)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Paroxysmal Dyspnea:

1.	Bronchodilator Agents (Bronchodilators)IBA 08/01/2008 - "The bases for diagnosis were ranked as follows: 1) recurrent paroxysmal dyspnea or symptoms such as wheezing and cough (86%); 2) detection of wheezing on auscultation (78%); 3) improvement in symptoms or auscultation findings after using bronchodilators (56%); 4) improvement in symptoms or auscultation findings after using inhaled corticosteroids (55%); 5) diagnosis of asthma by another physician (46%); and 6) spirometry findings (31%). "
2.	Adrenal Cortex Hormones (Corticosteroids)IBA 08/01/2008 - "The bases for diagnosis were ranked as follows: 1) recurrent paroxysmal dyspnea or symptoms such as wheezing and cough (86%); 2) detection of wheezing on auscultation (78%); 3) improvement in symptoms or auscultation findings after using bronchodilators (56%); 4) improvement in symptoms or auscultation findings after using inhaled corticosteroids (55%); 5) diagnosis of asthma by another physician (46%); and 6) spirometry findings (31%). "
3.	formoterol (Oxis)FDA Link 01/01/2009 - "The aim of this study was to examine whether asthma, cardiac or all-cause mortality and morbidity were increased with formoterol use. "
4.	Endothelin-1 (Endothelin 1)IBA 01/09/2009 - "Endothelin-1 overproduction has been implicated in a heterogeneous list of diseases including systemic and pulmonary hypertension, stroke and asthma, cardiac and renal failure. "
5.	Propranolol (Inderal)FDA LinkGeneric 10/01/1973 - "[Propranolol in attacks of paroxysmal dyspnea in the tetralogy of Fallot]."
6.	Prednisolone (Predate)FDA LinkGeneric 04/01/1991 - "[Clinical and physiological features of chronic pulmonary emphysema with paroxysmal dyspnea attacks masquerading as bronchial asthma--improvement of respiratory function after combination therapy of intravenous aminophylline and subcutaneous epinephrine following daily oral administration of prednisolone]."
7.	Pilocarpine (Ocusert)FDA LinkGeneric 08/01/2002 - "Pilocarpine must therefore be used with caution in patients with asthma, cardiac arrhythmia, iridocyclitis, and closed-angle glaucoma. "
8.	Immunoglobulin E (IgE)IBA 10/01/1992 - "Baseline spirometries, blood eosinophil counts, serum IgE levels, sputum eosinophil counts, family history of asthma, and history of paroxysmal dyspnea did not vary across responders and non-responders. "
9.	Epinephrine (Adrenaline)FDA LinkGeneric 04/01/1991 - "[Clinical and physiological features of chronic pulmonary emphysema with paroxysmal dyspnea attacks masquerading as bronchial asthma--improvement of respiratory function after combination therapy of intravenous aminophylline and subcutaneous epinephrine following daily oral administration of prednisolone]."
10.	Dexamethasone (Maxidex)FDA LinkGeneric 01/01/2012 - "She presented with new symptoms of exertional dyspnea, paroxysmal nocturnal dyspnea, and orthopnea after a 4th cycle of a bortezomib/dexamethasone-based chemotherapy. "

Therapies and Procedures

1.	Hemodilution 01/01/1943 - "THE RELATION OF POSTURAL HEMODILUTION TO PAROXYSMAL DYSPNEA."
2.	Renal Dialysis (Hemodialysis) 10/01/2001 - "We report the case of a patient undergoing long-term hemodialysis admitted to hospital for diagnosis of recurrent face and neck edema influenced by dialysis sessions with paroxysmal dyspnea. "
3.	Drug Therapy (Chemotherapy) 01/01/2012 - "She presented with new symptoms of exertional dyspnea, paroxysmal nocturnal dyspnea, and orthopnea after a 4th cycle of a bortezomib/dexamethasone-based chemotherapy. "
4.	Oral Administration 04/01/1991 - "[Clinical and physiological features of chronic pulmonary emphysema with paroxysmal dyspnea attacks masquerading as bronchial asthma--improvement of respiratory function after combination therapy of intravenous aminophylline and subcutaneous epinephrine following daily oral administration of prednisolone]."