Dysentery

Acute inflammation of the intestine associated with infectious DIARRHEA of various etiologies, generally acquired by eating contaminated food containing TOXINS, BIOLOGICAL derived from BACTERIA or other microorganisms. Dysentery is characterized initially by watery FECES then by bloody mucoid stools. It is often associated with ABDOMINAL PAIN; FEVER; and DEHYDRATION.

Also Known As:

Networked: 1128 relevant articles (48 outcomes, 114 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1.	Diarrhea
2.	Infection
3.	Measles
4.	Enteritis
5.	Amebic Dysentery (Amoebic Dysentery)

Experts

1.	Black, Robert E: 5 articles (03/2011 - 07/2004)
2.	Hampson, David J: 4 articles (11/2011 - 08/2002)
3.	Calzada, Fernando: 4 articles (05/2010 - 12/2006)
4.	Peng, Wei: 3 articles (11/2015 - 09/2008)
5.	Hampson, D J: 3 articles (01/2015 - 10/2000)
6.	Lazzerini, Marzia: 3 articles (01/2013 - 01/2008)
7.	Ronfani, Luca: 3 articles (01/2013 - 01/2008)
8.	Phillips, Nyree D: 3 articles (11/2011 - 08/2004)
9.	La, Tom: 3 articles (11/2011 - 08/2004)
10.	Sansonetti, Philippe J: 3 articles (09/2011 - 06/2002)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Dysentery:

1.	CarbadoxIBA 03/01/1973 - "Therapeutic efficacy of carbadox in field outbreaks of swine dysentery." 01/01/1987 - "Studies on the efficacy of Getroxel against Treponema hyodysenteriae and its role in the control of swine dysentery." 02/01/1973 - "Efficacy of carbadox in prevention of field outbreaks of swine dysentery." 01/01/2014 - "Carbadox is an in-feed antibiotic that is widely used in swine production to prevent dysentery and to improve feed efficiency. " 08/15/1990 - "Carbadox is a potentially effective prophylactic feed additive for the prevention of swine dysentery, but is mostly used in high dosages which are almost toxic for the animals, and used during unnecessary prolonged periods. "
2.	AntigensIBA 04/01/2000 - "These results indicate that CL antigen with high HA titer induces antibody production in cattle that provides effective protection against winter dysentery." 12/01/1988 - "The detection of Shigella antigens in feces in accordance with the results of the passive hemagglutination test is more effective than the bacteriological method for finding out persons infected with Shigella, especially in the absence of pronounced clinical manifestations of dysentery, and can be used in the study of the mechanism of the epidemic process. " 10/01/2002 - "Field study of bovine coronavirus vaccine enriched with hemagglutinating antigen for winter dysentery in dairy cows." 04/01/2000 - "Protection studies on winter dysentery caused by bovine coronavirus in cattle using antigens prepared from infected cell lysates." 10/01/1997 - "In this study, amplification of the invasion plasmid antigen H (ipaH) gene by PCR and standard culture methods was used to identify Shigella species or EIEC among 154 patients with dysentery, 154 age-matched controls, and family contacts in Thailand. "
3.	VaccinesIBA 07/01/1983 - "[Comparative immunomorphological study of the immunogenic activity of dysentery vaccines produced by different methods]." 01/01/1981 - "[Study of enteric dysentery vaccines and their efficacy on a rabbit intestinal loop model. " 10/01/1963 - "[STUDY ON DYSENTERY VACCINES]." 03/01/1949 - "Studies in dysentery vaccination; primary vaccination of children with polyvalent vaccines of Shigella." 10/01/1948 - "Studies in dysentery vaccination; primary vaccination of children with monovalent vaccines of Shigella."
4.	Anti-Bacterial Agents (Antibiotics)IBA 05/25/1963 - "1. CLINICAL STUDIES ON THE EFFECT OF ANTIBIOTICS IN DYSENTERY ON AGGLUTININ PRODUCTION]." 01/01/2011 - "Of these, 4, 232 (44.7%) were diagnosed with diarrhoea, with 130 of these being bloody (dysentery) therefore requiring antibiotics. " 04/01/2010 - "Antibiotics for the treatment of dysentery in children." 06/01/2007 - "Physicians might mistake some patients' clinical features of diarrhoea as features of dysentery, leading to unnecessary prescription of antibiotics." 09/01/2006 - "The current antibiotic guidelines in Fiji, recommend that antibiotics be used only for cases of moderate and severe dysentery. "
5.	tiamulinIBA 03/13/1982 - "Tiamulin at 30 ppm was shown to be highly effective in preventing the clinical signs of dysentery. " 06/21/1980 - "Tiamulin was found to be effective in the treatment of experimental swine dysentery when included in the drinking water at 22.5, 45 and 60 ppm for three and five days. " 10/31/1987 - "It was concluded that tiamulin was suitable for inclusion in the swine dysentery eradication programme in the GDR." 05/15/1986 - "Tiamulin in drinking water for treatment and development of immunity to swine dysentery." 09/10/1983 - "Tiamulin injection for the treatment of swine dysentery."
6.	Ciprofloxacin (Cipro)FDA LinkGeneric 12/01/2002 - "In this study twice daily ciprofloxacin for 3 days achieved clinical cure rates similar to those for the same dosage given for 5 days in children with Sd1 dysentery." 12/01/2002 - "This study compared the efficacy and safety of short course (3 days) and standard course (5 days) oral ciprofloxacin in children with Sd1 dysentery. " 10/01/2005 - "A case of haemolytic uraemic syndrome following dysentery due to ciprofloxacin-resistant Shigella dysenteriae serotype 1 is reported for the first time. " 12/01/2002 - "Children between 1 and 12 years of age with Sd1 dysentery were randomized to receive oral ciprofloxacin suspension 15 mg/kg every 12 h for 3 days followed by placebo for 2 days or ciprofloxacin suspension for 5 days. " 12/01/2002 - "Multicenter, randomized, double blind clinical trial of short course versus standard course oral ciprofloxacin for Shigella dysenteriae type 1 dysentery in children."
7.	Lincomycin (Lincocin)FDA Link 07/01/1978 - "All concentrations of lincomycin were effective for the treatment of swine dysentery by oral or by contact exposure. " 07/01/1978 - "Three experimental studies were conducted in 232 growing pigs (8 to 12 weeks old) to evaluate the therapeutic effects of various concentrations of lincomycin in drinking water, against swine dysentery experimentally transmitted, by oral inoculation or by contact-commingling exposure. " 02/01/1981 - "Therapeutic effects of parenteral administration of lincomycin on experimentally transmitted swine dysentery." 10/01/1979 - "Lincomycin levels for treatment of swine dysentery." 07/01/1978 - "The suggested optimal concentration was 33 mg of lincomycin/L of drinking water for the treatment of swine dysentery."
8.	RonidazoleIBA 07/01/1976 - "The addition of ronidazole to the drinking water at the concentration of 0.003% was effective for the treatment of experimentally induced swine dysentery in swine. " 07/01/1976 - "Ronidazole administered in the drinking water at concentrations of 0.012, 0.006, and 0.003% was effective for the treatment of swine dysentery. " 01/01/1985 - "Albino rats were used to study some remote side effects (total reproduction, embryotoxicity, and teratogenic action) of the Bulgaria Ronidazol-Pharmachim preparation, analogous to the one produced by the firm MS & D--USA (Ridzol 10 per cent water-soluble powder) used in veterinary practice as a prophylactic and therapeutic agent in the case of swine dysentery and turkey blackhead. " 03/01/1977 - "Clinical field evaluation of ronidazole for the treatment of swine dysentery." 07/01/1976 - "Ronidazole at concentrations of 0.0015% and 0.00075% aided in the treatment of swine dysentery and the development of immunity to the disease. "
9.	Formaldehyde (Formol)FDA Link 09/01/1977 - "The role of serum antitoxic antibody in protection against the dysentery caused by Shigella dysenteriae type 1 (Shiga's bacillus) was studied in monkeys fed 10(10) virulent organisms after parenteral immunization with a formalin-inactivated Shiga toxoid preparation standardized in mice. " 06/01/1943 - "Improved Technic for Isolation of Dysentery Bacteria from Stools by Formaldehyde Inactivation of Bacteriophage." 01/01/2015 - "Accordingly, FISH on formalin-fixed feces from clinically affected pigs can provide same-day identification and preliminary speciation of spirochetes associated with swine dysentery in North America. " 10/01/1998 - "pilosicoli in formalin-fixed colon tissue sections from pigs suffering from swine dysentery and porcine colonic spirochaetosis, respectively. " 10/01/1961 - "Concerning the formalin-alum vaccine of dysentery bacillus."
10.	Amdinocillin Pivoxil (Pivmecillinam)IBA 10/01/1995 - "To compare the efficacy of cefixime with that of pivamdinocillin in the treatment of adults with acute dysentery caused by Shigella infection. " 04/01/2010 - "We reviewed all literature reporting the effect of ciprofloxacin, ceftriaxone and pivmecillinam for the treatment of dysentery in children in the developing countries. " 04/01/2010 - "The antibiotics recommended by the WHO--ciprofloxacin, ceftriaxone and pivmecillinam--are effective in reducing the clinical and bacteriological signs and symptoms of dysentery and thus can be expected to decrease diarrhoea mortality attributable to dysentery." 04/01/2010 - "Ciprofloxacin, ceftriaxone and pivmecillinam are the antibiotics currently recommended by the World Health Organization (WHO) for the treatment of dysentery in children; yet there have been no reviews of the clinical effectiveness of these antibiotics in recent years. "

Therapies and Procedures

1.	Traditional Medicine (Folk Remedies) 12/04/2015 - "The Condalia buxifolia root bark infusion is used in traditional medicine in Brazil as antipyretic, anti-inflammatory and against dysentery. " 12/01/2015 - "salicaria has been long used in traditional medicine for chronic diarrhoea, dysentery, leucorrhoea and blood-spitting, genotoxic potential of the plant should be evaluated not only with regard to potential effects in the aquatic ecosystem, but also assessing its safe use as a medicinal herb. " 01/01/2015 - "The use of plants for the treatment of dysentery and other diseases in traditional medicine has increased on the basis of these rich traditional medicine systems. " 01/01/2014 - "(Oleaceae) has been commonly used in the traditional medicine in dysentery, diarrhoea and bellyache in China. " 06/01/2013 - "The sim fruit (Rhodomyrtus tomentosa) has long been used in folk medicine to treat diarrhoea, dysentery, and to boost the immune system. "
2.	Chinese Traditional Medicine (Traditional Chinese Medicine) 11/22/2013 - "The pestalotiopsones are fungal metabolites isolated from an endophytic fungus Pestalotiopsis sp. found in the mangrove Rhizophora mucronata, used in traditional Chinese medicine to treat symptoms of dysentery. " 03/13/2015 - "Galla chinensis has been popularly used in traditional Chinese medicine which is beneficial for the treatment of various diseases, such as inflammation, dysentery, toxicosis and sore. " 01/01/2001 - "It is widely used in traditional Chinese medicine as an antimicrobial in the treatment of dysentery and infectious diarrhea. " 01/01/2012 - "Plants belonging to the genus Broussonetia (Moraceae), which grow naturally in Asian and Pacific countries, have long been used in traditional Chinese medicine to treat various conditions, particularly tinea, dysentery, hernia and oedema. " 08/01/2008 - "Radix Sophorae Flavescentis is a traditional Chinese medicine, which is the roots of Sophora flavescens and is used to treat abscess, dysentery, eczema and skin itch. "
3.	Oral Administration 12/01/1995 - "Shedder swine were inoculated with S hyodysenteriae by oral administration of 20 g of diced colon from swine infected with swine dysentery. " 09/01/1987 - "The method makes preconditions for the production of a live attenuated dysentery vaccine for oral administration." 08/01/1970 - "Dysentery produced by oral administration of the colonic contents of cynomolgus monkeys infected with Shigella flexneri 2a." 08/01/1976 - "In contrast to the pattern of disease seen after oral administration, cecal inoculation resulted in clinical disease in 64% of animals, of which 94% manifested dysentery alone, rarely preceded by mild diarrhea. " 05/01/1965 - "The parent Shigella strain caused a fatal enteric infection when fed to starved guinea pigs, and signs of dysentery followed its oral administration to monkeys. "
4.	Injections 11/01/1984 - "In monkey tests two injections of ribosomal vaccine obtained by PEG fractionation ensured a high protective effect against dysentery. " 09/01/1978 - "The authors studied the immunological shifts in the blood and saliva of 357 adults immunized with live enteral dysentery Sonne vaccine from a spontaneous mutant according to different schemes (1, 2, 3, 4 injections at 2--3-day intervals. " 01/25/1902 - "THE TREATMENT OF DYSENTERY BY RECTAL INJECTIONS." 03/01/1949 - "Studies in dysentery vaccination; response of children to booster injections of Shigella vaccines." 10/31/1987 - "Swine dysentery control in the German Democratic Republic and the suitability of injections of tiamulin for the programme."
5.	Catheters 06/01/2007 - "Consecutive pathological and immunological alterations during experimentally induced swine dysentery - a study performed by repeated endoscopy and biopsy samplings through an intestinal cannula." 06/01/2007 - "Endoscopy through an intestinal cannula made it possible to follow the development of intestinal alterations in vivo and describe the sequential events during the course of swine dysentery. " 01/01/1999 - "Ten nonpregnant, BCV seropositive, adult dairy cows were inoculated with winter dysentery (WD) (n = 8) or calf diarrhea (CD) (n = 2) strains of BCV intranasally and orally (n = 2) or through a surgically-placed duodenal catheter (n = 8) with and without dexamethasone treatment or feeding ice water. "