Duodenal Obstruction

Hindrance of the passage of luminal contents in the DUODENUM. Duodenal obstruction can be partial or complete, and caused by intrinsic or extrinsic factors. Simple obstruction is associated with diminished or stopped flow of luminal contents. Strangulating obstruction is associated with impaired blood flow to the duodenum in addition to obstructed flow of luminal contents.

Also Known As:

Networked: 332 relevant articles (15 outcomes, 15 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1.	Vomiting
2.	Pancreatic Neoplasms (Pancreatic Cancer)
3.	Carcinoma (Carcinomatosis)
4.	Pain (Aches)
5.	Inflammation

Experts

1.	Shin, Ji Hoon: 3 articles (07/2008 - 02/2006)
2.	Song, Ho-Young: 3 articles (07/2008 - 02/2006)
3.	Lee, Sang Hyub: 2 articles (02/2015 - 06/2013)
4.	Li, Bing: 2 articles (01/2015 - 10/2013)
5.	Baron, Todd H: 2 articles (01/2015 - 09/2010)
6.	Park, Young Soo: 2 articles (06/2013 - 11/2008)
7.	Lee, Moon Sung: 2 articles (12/2012 - 10/2009)
8.	Moon, Jong Ho: 2 articles (12/2012 - 10/2009)
9.	Hong, Su Jin: 2 articles (12/2012 - 10/2009)
10.	Choi, Hyun Jong: 2 articles (12/2012 - 10/2009)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Duodenal Obstruction:

1.	Familial duodenal atresiaIBA 01/01/2015 - "Patients with refractory benign duodenal stenosis and malignant duodenal obstruction. " 08/01/2014 - "An upper gastrointestinal series revealed complete duodenal obstruction and duodenal atresia was confirmed at surgery. " 10/01/2008 - "There are few reports in the literature on the use of a laparoscopic approach for duodenal obstruction, particularly for duodenal atresia. " 05/01/2001 - "Duodenal atresia is associated with a higher incidence of associated congenital malformations than jejunoileal atresia, supporting the hypothesis that the duodenal obstruction occurs early in fetal life. " 01/01/2004 - "Palliative treatment for duodenal stenosis with an enteral stent is effective in enhancing the quality of life of patients with duodenal obstruction. "
2.	Adrenal Cortex Hormones (Corticosteroids)IBA 07/01/1998 - "Idiopathic retroperitoneal fibrosis with duodenal obstruction successfully treated with corticosteroids." 12/03/1966 - "Idiopathic retroperitoneal fibrosis with protein-losing enteropathy and duodenal obstruction successfully treated with corticosteroids." 12/18/1965 - " of these patients had symptoms of severe duodenal obstruction and were relieved by bypass procedures and vagotomy; one required surgery because of co-existent obstructive ileal disease: and two patients have improved on corticoids and salicylazosulfapyridine without surgery.In"
3.	Carbon MonoxideIBA 05/01/1955 - "Duodenal obstruction due to annular pancreas in a patient with co-existing gastric ulcer." 12/18/1965 - " of these patients had symptoms of severe duodenal obstruction and were relieved by bypass procedures and vagotomy; one required surgery because of co-existent obstructive ileal disease: and two patients have improved on corticoids and salicylazosulfapyridine without surgery.In"
4.	nitinolIBA 07/01/2006 - "Peroral placement of nitinol stents is an effective and easy method of mitigation for most patients with malignant gastro-duodenal obstructions. " 02/01/2006 - "Under fluoroscopic guidance, 82 patients (56 male and 26 female; mean age, 62.3 y) with malignant duodenal obstructions were treated with per oral placement of four types of self-expandable nitinol stents. " 02/01/2006 - "To assess the efficacy of fluoroscopic per oral placement of self-expandable nitinol stents in the palliative treatment of malignant duodenal obstructions. " 02/01/2006 - "Fluoroscopic per oral placement of self-expandable nitinol stents is an effective palliative treatment for malignant duodenal obstructions." 02/01/2006 - "Malignant duodenal obstructions: palliative treatment using self-expandable nitinol stents."
5.	Sulfasalazine (Azulfidine)FDA LinkGeneric 12/18/1965 - " of these patients had symptoms of severe duodenal obstruction and were relieved by bypass procedures and vagotomy; one required surgery because of co-existent obstructive ileal disease: and two patients have improved on corticoids and salicylazosulfapyridine without surgery.In"
6.	Kaposiform HemangioendotheliomaIBA 06/01/2014 - "Pancreatic kaposiform hemangioendothelioma presenting with duodenal obstruction and kasabach-merritt phenomenon: a neonate cured by whipple operation."
7.	BariumIBA 10/01/2010 - "Diagnostic methods for identifying duodenal obstruction by the SMA include upper gastrointestinal barium contrast studies, computed tomography scans, or angiography of the aorta with either contrast or magnetic resonance angiography. " 03/01/1999 - "Late diagnosis was made in eight babies and led to prolonged hospitalization (mean 20 days), although duodenal obstruction was demonstrated by barium study in all 13 patients. " 01/01/1992 - "A review of barium meal studies in 32 cases of congenital intrinsic duodenal obstruction (CDO) from the Adelaide Children's Hospital was performed to assess and measure pre and post operative duodenal dilatation. " 01/01/2015 - "A barium swallow revealed a duodenal obstruction at D3. " 05/01/2004 - "In all children, the diagnosis was made from plain abdominal X-ray, which showed the classic double-bubble appearance, and barium meal, which showed duodenal obstruction. "
8.	Congenital diaphragmatic herniaIBA 12/01/1997 - "Wandering spleen presenting as duodenal obstruction after repair of congenital diaphragmatic hernia." 02/01/2014 - "25 newborns participated on this study; among the treated conditions, congenital diaphragmatic hernia (1), Esophageal Atresia (4 complete repairs and 2 fistula ligation), duodenal obstruction (7), Gastroesophageal reflux disease (6 Nissen procedures, 4 including gastrostomy), Laparoscopic gastrostomy (2) Intestinal obstruction (two bowel resections, end to end anastomosis), and Hypertrophic pyloric stenosis (1). "
9.	Annular pancreasIBA 01/01/2015 - "Laparoscopic diagnosis and treatment of neonates with duodenal obstruction associated with an annular pancreas: report of 11 cases." 09/01/2012 - "Annular pancreas can initially present in childhood or adulthood with symptoms of duodenal obstruction and is diagnosed using a variety of imaging modalities. " 02/01/2012 - "Duodenal bypass is the procedure of choice for treating duodenal obstruction caused by the annular pancreas in both children and adults. " 01/01/2012 - "Annular pancreas associated with duodenal obstruction." 04/01/2011 - " report a case of 61 year female presenting with duodenal obstruction due to annular pancreas."
10.	DiamondIBA 01/01/2009 - "Kimura's diamond-shaped-duodenoduodenostomy (DSD) is a known technique for the correction of congenital intrinsic duodenal obstruction. " 10/01/1977 - "A diamond-shaped side-to-side duodenoduodenal anastomosis has been performed in nine consecutive cases of congenital duodenal obstruction, with satisfactory results. " 10/01/1977 - "Diamond-shaped anastomosis for congenital duodenal obstruction." 09/01/1990 - "During the period between 1974 and 1988 44 patients were treated for congenital intrinsic duodenal obstruction using a diamond-shaped anastomosis (35 atresias, including two multiple atresias and nine stenoses). " 12/01/1997 - "Analysis of data obtained from the patients revealed that the duodenal obstruction was the most successfully treated by diamond-shaped duodenoduodenostomy, jejunal obstruction by resection of the dilated oral blind end, tapering jejunoplasty and ileal obstruction by resection of the dilated blind end and anastomosis or ileostomy in case with peritonitis. "

Therapies and Procedures

1.	Stents 02/01/2015 - "The newly designed stent is associated with a high degree of technical success and good clinical outcome and may be clinically effective in the management of malignant distal duodenal obstruction." 06/01/2013 - "The use of uncovered stents may be a preferred option for duodenal obstruction secondary to pancreaticobiliary malignancies, since they were effective in preventing stent migration and tended to have longer patency than covered stents. " 08/01/2007 - "Placement of a self-expandable metallic stent is clinically effective in patients with unresectable gastric outlet or duodenal obstruction. " 05/01/2002 - "The aim of the study was to determine the efficacy of the endoscopic placement of metal self expanding duodenal stents for the palliation of malignant duodenal obstruction. " 04/01/2003 - "This study reports our experience with the use of self-expanding metal stents in the palliation of malignant gastric duodenal obstruction. "
2.	Gastric Bypass (Roux-en-Y Gastric Bypass) 01/01/2008 - "However, debate continues concerning the efficacy of gastrojejunostomy at preventing duodenal obstruction. " 06/01/2012 - "Endoscopic vs. laparoscopic gastrojejunostomy for duodenal obstruction: a randomized study in a porcine model." 02/01/2012 - "The purpose of this study was to develop a model for an entirely endoscopic gastrojejunostomy to treat duodenal obstruction, and to compare this with the laparoscopic technique. " 02/01/2012 - "Endoscopic vs. laparoscopic gastrojejunostomy for duodenal obstruction: a randomized study in a porcine model." 12/01/2014 - "Duodenal obstruction by compression from the superior mesenteric artery (SMA) can be managed using minimally invasive techniques initially developed for bariatric patients requiring gastric bypass. "
3.	Vagotomy 07/01/1997 - "Duodenal obstruction was relieved by gastrojejunostomy in eight patients, gastrojejunostomy and vagotomy in eight patients, gastroduodenostomy and vagotomy in two patients, vagotomy with Finney pyloroplasty in one patient, duodenoplasty with vagotomy in one patient and Whipple procedure in four patients. " 06/01/1983 - "Indeed, choledochoduodenostomy, which has been carried out in combination with either gastrojejunostomy and vagotomy in the presence of duodenal obstruction or with pericystojejunostomy for the treatment of pancreatic pseudocyst, has been shown to be the treatment of choice." 06/01/1982 - "In the third patient, who had mural inflammation in the distal stomach and presumably in the duodenum as well, vagotomy and gastrojejunostomy relieved severe duodenal obstruction but not pain. " 12/18/1965 - " of these patients had symptoms of severe duodenal obstruction and were relieved by bypass procedures and vagotomy; one required surgery because of co-existent obstructive ileal disease: and two patients have improved on corticoids and salicylazosulfapyridine without surgery.In"
4.	Palliative Care (Palliative Medicine) 12/01/2012 - "Uncovered SEMS placement is effective as a first-line palliative therapy for inoperable malignant duodenal obstruction. " 12/01/2012 - "Uncovered self-expandable metallic stent placement as a first-line palliative therapy in unresectable malignant duodenal obstruction." 04/01/2006 - "We evaluated palliative treatment for unresectable malignant stomach pyloric region and the duodenal obstruction using covered self-expandable metallic stent (SEMS). " 04/01/2003 - "Self-expandable metal stents placed endoscopically provide a safe, less invasive palliative treatment option with good clinical outcome in the management of malignant gastric outlet-duodenal obstruction." 07/01/2002 - "Use of stents in the palliative treatment of malignant gastric outlet and duodenal obstruction."
5.	Laparotomy 09/01/2013 - "We conclude that the umbilical approach with this novel U-to-u umbilicoplasty to treat congenital duodenal obstruction in the newborn is a safe and effective method and a good alternative to the standard transverse laparotomy approach." 07/01/2015 - "Congenital duodenal obstruction is traditionally managed by laparotomy. " 01/01/2014 - "She had a history of laparotomy because of duodenal obstruction 2 years ago. " 10/01/2012 - "But, after laparotomy, she was finally diagnosed as a case of recurrent duodenal obstruction due to Congenital Duodenal Web (Wind-Soak Variety) with a central hole in the fourth part of the duodenum. " 12/01/2011 - "Exploratory laparotomy unexpectedly revealed a high insertion of the duodenum at the ligament of Treitz, with upward displacement and SMA compression leading to duodenal obstruction. "