A catecholamine derivative with specificity for BETA-1 ADRENERGIC RECEPTORS. It is commonly used as a cardiotonic agent after CARDIAC SURGERY and during DOBUTAMINE STRESS ECHOCARDIOGRAPHY.
Also Known As:
Boehringer Ingelheim Brand of Dobutamine Hydrochloride; Dobucor; Dobuject; Dobutamin Fresenius; Dobutamin Hexal; Dobutamin Solvay; Dobutamin-ratiopharm; Dobutamina Inibsa; Dobutamina Rovi; Dobutamine (+)-Isomer; Dobutamine Hydrobromide; Dobutamine Hydrochloride; Dobutamine Lactobionate; Dobutamine Phosphate (1:1) Salt, (-)-Isomer; Dobutamine Tartrate; Dobutamine Tartrate (1:1), (R-(R*,R*))-Isomer; Dobutamine Tartrate (1:1), (S-(R*,R*))-Isomer; Dobutamine, (-)-Isomer; Dobutamine, Phosphate (1:1) Salt (+)-Isomer; Dobutrex; Eli Lilly Brand of Dobutamine Hydrochloride; Fresenius Brand of Dobutamine Hydrochloride; Hexal Brand of Dobutamine Hydrochloride; Inibsa Brand of Dobutamine Hydrochloride; Irisfarma Brand of Dobutamine Hydrochloride; Juste Brand of Dobutamine Hydrochloride; Kendrick Brand of Dobutamine Hydrochloride; Lilly 81929; Lilly Brand of Dobutamine Hydrochloride; Oxiken; Pisa Brand of Dobutamine Hydrochloride; Posiject; Rovi Brand of Dobutamine Hydrochloride; Solvay Brand of Dobutamine Hydrochloride; ratiopharm Brand of Dobutamine Hydrochloride; Dobutamin ratiopharm; Hydrobromide, Dobutamine; Hydrochloride, Dobutamine; Lactobionate, Dobutamine; Tartrate, Dobutamine; 1,2-Benzenediol, 4-(2-((3-(4-hydroxyphenyl)-1-methylpropyl)amino)ethyl)-, (+-)-
Networked: 3449 relevant articles (249 outcomes, 645 trials/studies)

Relationship Network

Drug Context: Research Results


1. Bax, Jeroen J: 58 articles (12/2015 - 06/2002)
2. Elhendy, Abdou: 51 articles (12/2011 - 06/2002)
3. Poldermans, Don: 50 articles (12/2011 - 06/2002)
4. Schinkel, Arend F L: 37 articles (10/2015 - 06/2002)
5. van Domburg, Ron T: 31 articles (10/2015 - 06/2002)
6. Bax, J J: 26 articles (05/2007 - 01/2000)
7. Marwick, Thomas H: 24 articles (06/2014 - 06/2002)
8. Poldermans, D: 20 articles (05/2007 - 06/2000)
9. Picano, Eugenio: 19 articles (02/2013 - 02/2003)
10. Biagini, Elena: 19 articles (12/2011 - 03/2004)

Related Diseases

1. Heart Failure
2. Myocardial Infarction
01/01/2000 - "We conclude that the restored positive T waves in Q-wave myocardial infarction indicate a significantly greater amount of viable myocardium than the negative T waves, showing better regional wall motion improvement with low-dose dobutamine stress."
12/01/1991 - "To assess the effects of coronary revascularization on viable but noncontractile myocardium, we examined 21 patients with a documented anterior acute myocardial infarction who had a significant improvement in wall motion abnormality evaluated by two-dimensional echocardiography in the infarct-related artery in response to low-dose dobutamine infusion. "
09/01/2000 - "The overall positive predictive value of improved regional wall motion after CABG did not vary with left ventricular ejection fraction, a history of myocardial infarction, or beta blocker use, and it varied little with diabetic status (range, 0.86-0.96) if regional wall motion improved with low-dose dobutamine before CABG. "
12/01/1991 - "We conclude that: (1) low-dose dobutamine infusion may identify viable but noncontractile myocardium in patients with acute myocardial infarction and (2) in these patients revascularization causes a greater improvement in left ventricular function over time when compared with a nonrevascularized group."
12/01/1997 - "Previous studies have shown that low dose dobutamine echocardiography was accurate for detecting reversible dysfunction after acute myocardial infarction (MI) but did not determine whether accuracy was improved by peak dose findings or influenced by the test interval or clinical or angiographic factors. "
3. Coronary Artery Disease (Coronary Atherosclerosis)
4. Ischemia
5. Left Ventricular Dysfunction

Related Drugs and Biologics

1. Dopamine (Intropin)
2. simendan (Levosimendan)
3. Amrinone (Amrinon)
4. Norepinephrine (Noradrenaline)
5. Nitroprusside (Sodium Nitroprusside)
6. Epinephrine (Adrenaline)
7. Milrinone (Primacor)
8. Dipyridamole (Persantine)
9. Enoximone
10. Brain Natriuretic Peptide (Natrecor)

Related Therapies and Procedures

1. Angioplasty (Angioplasty, Transluminal)
2. Resuscitation
3. Intravenous Infusions
4. Thrombolytic Therapy
5. Cardiopulmonary Bypass (Heart-Lung Bypass)