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Circular DNA

Any of the covalently closed DNA molecules found in bacteria, many viruses, mitochondria, plastids, and plasmids. Small, polydisperse circular DNA's have also been observed in a number of eukaryotic organisms and are suggested to have homology with chromosomal DNA and the capacity to be inserted into, and excised from, chromosomal DNA. It is a fragment of DNA formed by a process of looping out and deletion, containing a constant region of the mu heavy chain and the 3'-part of the mu switch region. Circular DNA is a normal product of rearrangement among gene segments encoding the variable regions of immunoglobulin light and heavy chains, as well as the T-cell receptor. (Riger et al., Glossary of Genetics, 5th ed & Segen, Dictionary of Modern Medicine, 1992)
Also Known As:
DNA, Circular; Circular DNAs; DNAs, Circular
Networked: 578 relevant articles (24 outcomes, 28 trials/studies)

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Bio-Agent Context: Research Results

Experts

1. Dandri, Maura: 14 articles (01/2022 - 09/2006)
2. Guo, Haitao: 12 articles (11/2022 - 08/2012)
3. Zoulim, Fabien: 12 articles (01/2022 - 02/2002)
4. Protzer, Ulrike: 7 articles (01/2022 - 01/2008)
5. Yuan, Zhenghong: 7 articles (01/2022 - 02/2014)
6. Watashi, Koichi: 7 articles (12/2021 - 09/2014)
7. Cai, Dawei: 6 articles (01/2022 - 08/2012)
8. Seto, Wai-Kay: 6 articles (01/2022 - 01/2017)
9. Yuen, Man-Fung: 6 articles (01/2022 - 10/2006)
10. Baumert, Thomas F: 6 articles (12/2021 - 12/2003)

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1. Infections
2. Chronic Hepatitis B
3. Hepatocellular Carcinoma (Hepatoma)
4. Hepatitis B
5. Reinfection

Related Drugs and Biologics

1. Antiviral Agents (Antivirals)
2. Hepatitis B Surface Antigens (HBsAg)
3. DNA (Deoxyribonucleic Acid)
4. RNA (Ribonucleic Acid)
5. Biomarkers (Surrogate Marker)
6. Hepatitis B Core Antigens
7. pgRNA
8. Proteins (Proteins, Gene)
9. Messenger RNA (mRNA)
10. Nucleosides

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1. Therapeutics
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