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DNA Virus Infections

Subscribe to New Research on DNA Virus Infections

Also Known As:

Infections, DNA Virus; DNA Virus Infection; Infection, DNA Virus; Virus Infection, DNA; Virus Infections, DNA

Networked: 41 relevant articles (2 outcomes, 2 trials/studies)

Relationship Network

Disease Context: Research Results

Virus Diseases: 1820
- DNA Virus Infections: 41

Related Diseases

1.	Leukemia
2.	Infection
3.	Acquired Immunodeficiency Syndrome (AIDS)
4.	HIV Infections (HIV Infection)
5.	Papilloma (Papillomatosis)

Experts

1.	Chen, Zhijian J: 3 articles (09/2013 - 02/2013)
2.	Sun, Lijun: 3 articles (09/2013 - 02/2013)
3.	Wu, Jiaxi: 3 articles (09/2013 - 02/2013)
4.	De Clercq, Erik: 3 articles (01/2013 - 09/2008)
5.	Ferguson, Brian J: 2 articles (12/2015 - 01/2013)
6.	Du, Fenghe: 2 articles (02/2013 - 02/2013)
7.	Chen, Xiang: 2 articles (02/2013 - 02/2013)
8.	Huang, Tianzhi: 2 articles (01/2013 - 01/2012)
9.	Zhang, Xiaobo: 2 articles (01/2013 - 01/2012)
10.	Hupp, Ted R: 2 articles (11/2009 - 05/2009)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to DNA Virus Infections:

1.	CytosineIBA 05/01/2011 - "Treatment of BKV nephropathy with cidofovir (CDV) {(S)-1-[3-hydroxy-2-(phosphonomethoxy)propyl]cytosine (HPMPC)}, an acyclic phosphonate analogue of dCMP with a broad antiviral activity against DNA virus infections, has been proposed. " 07/01/1977 - "Certain D-arabinosyl nucleosides, notably arabinosyl cytosine (araC) and arabinosyl adenine (araA), are useful in the treatment of certain leukemias and some DNA virus infections, respectively. " 12/01/1976 - "Certain D-arabinosyl nucleosides, notably D-arabinosyl cytosine (araC) and D-arabinosyl adenine (araA), are useful in the treatment of certain leukemias and some DNA virus infections, respectively. "
2.	NucleosidesIBA 07/01/1977 - "Certain D-arabinosyl nucleosides, notably arabinosyl cytosine (araC) and arabinosyl adenine (araA), are useful in the treatment of certain leukemias and some DNA virus infections, respectively. " 12/01/1976 - "Certain D-arabinosyl nucleosides, notably D-arabinosyl cytosine (araC) and D-arabinosyl adenine (araA), are useful in the treatment of certain leukemias and some DNA virus infections, respectively. "
3.	Adenine FDA LinkGeneric 07/01/1977 - "Certain D-arabinosyl nucleosides, notably arabinosyl cytosine (araC) and arabinosyl adenine (araA), are useful in the treatment of certain leukemias and some DNA virus infections, respectively. " 12/01/1976 - "Certain D-arabinosyl nucleosides, notably D-arabinosyl cytosine (araC) and D-arabinosyl adenine (araA), are useful in the treatment of certain leukemias and some DNA virus infections, respectively. "
4.	RNA (Ribonucleic Acid)IBA 03/01/1999 - "Recent studies in murine models of both RNA and DNA virus infections have begun to shed new light on the potential function for TCRgammadelta cells in antiviral immunity. " 09/01/2015 - "While dsRNA staining was primarily observed in the cytoplasm, nuclear staining was also present in some RNA and DNA virus infections. " 01/01/2015 - "Our results indicate that chTRAF3 plays important roles in defending against both RNA and DNA virus infection. " 07/17/2012 - "Moreover, LSm14A is essential for early-phase induction of IFN-β after either RNA or DNA virus infection. " 03/01/2007 - "Following the conceptual development of virus resistance strategies ranging from coat protein-mediated interference of virus propagation to RNA-mediated virus gene silencing, much progress has been achieved to protect plants against RNA and DNA virus infections. "
5.	Drug CombinationsIBA 02/01/1965 - "FURTHER STUDIES OF DRUG COMBINATIONS FOR COMPLETE CURE OF DNA VIRUS INFECTION IN CULTURED CELLS." 08/01/1964 - "COMPLETE CURE OF DNA VIRUS INFECTION IN CULTURED CELLS BY DRUG COMBINATIONS."
6.	DNA (Deoxyribonucleic Acid)IBA 02/15/2013 - "DNA transfection or DNA virus infection of mammalian cells also triggered cGAMP production. " 12/16/2010 - "However, Riplet was dispensable for the production of IFN in response to B-DNA and DNA virus infection. " 01/01/1987 - "There is now evidence that members of all five families of double stranded DNA-containing human viruses have been associated with unusual clinical manifestations in AIDS patients, and the significance of DNA virus infections in patients with AIDS is discussed." 02/15/2013 - "Knockdown of cGAS inhibited IRF3 activation and interferon-β induction by DNA transfection or DNA virus infection. " 09/20/2013 - "Here, we show that cells from cGAS-deficient (cGas(-/-)) mice, including fibroblasts, macrophages, and dendritic cells, failed to produce type I interferons and other cytokines in response to DNA transfection or DNA virus infection. "
7.	cidofovir (Vistide)FDA Link 11/01/2002 - "An increasing number of reports have appeared on the use of cidofovir for the treatment of other severe DNA virus infections in immunocompromised patients. " 11/01/2002 - "Role of cidofovir in the treatment of DNA virus infections, other than CMV infections, in immunocompromised patients." 04/01/2007 - "Although formally approved only for the treatment of human cytomegalovirus (HCMV) retinitis in AIDS patients, cidofovir has been used successfully in the treatment of various other DNA virus infections, particularly human papilloma virus (HPV)-associated lesions. " 05/01/2011 - "Treatment of BKV nephropathy with cidofovir (CDV) {(S)-1-[3-hydroxy-2-(phosphonomethoxy)propyl]cytosine (HPMPC)}, an acyclic phosphonate analogue of dCMP with a broad antiviral activity against DNA virus infections, has been proposed. " 01/01/2013 - "These compounds have revolutionized the antiviral drug field with several drugs that have been approved for the treatment of various DNA virus infections (cidofovir), hepatitis B (adefovir), and AIDS (HIV infection; tenofovir). "
8.	InterferonsIBA 02/15/2013 - "Knockdown of cGAS inhibited IRF3 activation and interferon-β induction by DNA transfection or DNA virus infection. " 12/01/2007 - "Our data suggest that IFN-alpha-induced antiviral program is able to discriminate host cellular DNA from episomal viral DNA and might represent a novel pathway of interferon mediate innate defense against DNA virus infections." 10/30/1986 - "Here we report that both TNF-alpha and TNF-beta have antiviral activity and synergize with interferons (IFNs) in the induction of resistance to both RNA and DNA virus infection in diverse cell types. " 01/01/2010 - "This has prompted me to highlight some of the hallmarks that played an important role in my own search of a selective therapy of viral infections: i.e., the induction of interferon by double-stranded RNA [such as poly(I).poly(C)], allowing the cloning and expression of beta-interferon; the discovery of the reverse transcriptase (RT) (and HIV as a retrovirus depending for its replication on RT), allowing the identification and development of a wide variety of RT inhibitors, nowadays used for the treatment of AIDS; the specificity of herpesvirus inhibitors such as acyclovir and BVDU, in the treatment of HSV and VZV infections; the role of acyclic nucleoside phosphonates (tenofovir, adefovir and cidofovir) in the treatment of HIV, HBV and DNA virus infections; and that of the NNRTIs (leading from TIBO to rilpivirine) as an essential part of the current anti-HIV drug cocktails. "
9.	Phosphotransferases (Kinase)IBA 08/12/2015 - "Receptor interacting protein kinase-3 (RIP3) is an essential kinase for necroptotic cell death signaling and has been implicated in antiviral cell death signaling upon DNA virus infection. " 06/14/2007 - "DNA virus infection can elicit the DNA damage response in host cells, including ATM kinase activation and H2AX phosphorylation. " 05/01/2009 - "We demonstrate that distinct stress-activated kinases, including ataxia telangiectasia mutated (ATM), casein kinase 1 (CK1) and AMP-activated protein kinase (AMPK), mediate phosphorylation of a key phospho-acceptor site in the p53 transactivation domain in response to diverse stresses including ionizing radiation, DNA virus infection, and elevation in the intracellular AMP/ATP ratio. "
10.	tenofovir FDA Link 01/01/2013 - "These compounds have revolutionized the antiviral drug field with several drugs that have been approved for the treatment of various DNA virus infections (cidofovir), hepatitis B (adefovir), and AIDS (HIV infection; tenofovir). " 09/01/2006 - "It describes the development of research which led to the discovery of several structurally related potent antivirals and ultimately resulted in the development of drugs directed against HIV, HBV and DNA-virus infections in general, namely adefovir, cidofovir and tenofovir. " 01/01/2010 - "This has prompted me to highlight some of the hallmarks that played an important role in my own search of a selective therapy of viral infections: i.e., the induction of interferon by double-stranded RNA [such as poly(I).poly(C)], allowing the cloning and expression of beta-interferon; the discovery of the reverse transcriptase (RT) (and HIV as a retrovirus depending for its replication on RT), allowing the identification and development of a wide variety of RT inhibitors, nowadays used for the treatment of AIDS; the specificity of herpesvirus inhibitors such as acyclovir and BVDU, in the treatment of HSV and VZV infections; the role of acyclic nucleoside phosphonates (tenofovir, adefovir and cidofovir) in the treatment of HIV, HBV and DNA virus infections; and that of the NNRTIs (leading from TIBO to rilpivirine) as an essential part of the current anti-HIV drug cocktails. "

Therapies and Procedures

1.	Transplantation (Transplant Recipients) 04/01/2010 - "Etiology of DNA virus infections in liver transplant recipients with neonatal hepatitis." 09/01/2005 - "No difference was observed between the two treatment groups with respect to detection of CMV DNA, virus infections other than CMV, acute rejection episodes, and serum creatinine levels at 3 and 6 months following transplantation. "
2.	Transplants (Transplant) 12/01/1981 - "A number of functional similarities exist between the chicken MHC and that of other species such as regulation of graft rejection, graft-versus-host reaction (GVHR) and mixed lymphocyte reactions (MLR), mitogenic and immune responsiveness and resistance to RNA and DNA virus infection. "