Dimethylformamide

11/01/1981 - "Protection against hyperthermic cell killing of mouse mammary adenocarcinoma cells in vitro by N,N-dimethylformamide."
07/01/1981 - "Selective modification of the X ray survival response of two mouse mammary adenocarcinoma sublines by N,N-dimethylformamide."
10/01/1990 - "Human colonic adenocarcinoma DLD-1 cells were grown under conditions which induce characteristics of differentiated cells using medium containing 0.8% N,N-dimethylformamide in order to study alterations in glycosphingolipid glycosyltransferase activities during this process. "
01/01/1995 - "It has previously been observed that allyl isothiocyanate, a compound naturally present in the diet, is more cytotoxic toward the human colorectal adenocarcinoma cell line HT29 in its control transformed state than after exposure to sodium butyrate or to dimethylformamide, which slow growth and induce differentiation (detransformation). "
10/01/1990 - "Alteration of lacto-series glycolipid glycosyltransferase activities in human colonic adenocarcinoma DLD-1 cells after culture in N,N-dimethylformamide-containing medium."

04/01/2017 - "The ultrasound-assisted extraction of Ixora coccinea flowers improved of the ursolic acid isolationMethanolic extract from flowers of I. coccinea provided, by ultrasound irradiation, after KOH-impregnated silica in chromatography column, the ursolic acid in 35% yieldThe ursolic acid and four derivatives were prepared and assayed against two lung cancer and four leukaemia cell linesThe ursolic acid and their 3-oxo-derivative, in general, were more cytotoxic when compared to cisplatin, used as positive control Abbreviations used: MTT: 3,4,5-dimethylthiazol-2-yl-2,5-diphenyltetrazolium bromide, RP: reverse phase, TLC: thin layer chromatography, KOH: potassium hydroxide, IR: infrared, DMF: dimethylformamide, DMSO: dimethyl sulfoxide, TEA: triethylamine, RT: room temperature, EtOAc: ethyl acetate, MeOH: methanol, i-PrOH: iso-propanol, NMR: nuclear magnetic resonance, MDR: multiple drug resistance, RPMI: Roswell Park Memorial Institute."

03/01/1987 - "Dimethylformamide has been used as a model inducer in carcinoma and fibroblastic models. "
10/01/1985 - "N,N-dimethylformamide (DMF) induces differentiation of human colon carcinoma (DLD-1) cells in culture and reduces their tumorigenicity in nude mice. "
10/01/1985 - "Ultrastructural evidence of dimethylformamide-induced differentiation of cultured human colon carcinoma cells. "
01/01/1982 - "Alteration of the survival response of two human colon carcinoma subpopulations to x-irradiation by N,N-dimethylformamide."
03/15/1980 - "Cells from these lines and clones and cells from an established human colon carcinoma cell line were treated in vitro with N,N-dimethylformamide (DMF) and were compared to untreated cells according to two general sets of criteria. "

04/20/2023 - "In this paper, the clinical data of a case of accidental poisoning of dimethylformamide in a traffic accident was analyzed. "
04/20/2023 - "[A case of dimethylformamide poisoning caused by skin contact]."
12/01/2020 - "Excessive exposure to N,N-dimethylformamide (DMF) can lead to occupational liver poisoning in workers; however, the underlying mechanism is not fully clarified. "
12/20/2018 - "Objective: By analyzing the examination results of physical examination of workers exposed to DMF among 32 factories in some areas of a province, to investigate the working years of dimethylformamide (DMF) poisoning and the impact on the health status of exposed workers, and to explore the targeted intervention strategies. "
11/20/2016 - "[Clinical analysis of acute dimethylformamide poisoning]."

08/01/2007 - "29 (1990) 5197-5200, for synthesis and structural characterization, DMF=dimethylformamide] (NSC #624662) by using a panel of ca. 50 human cancer cells, showed growth inhibition factor GI(50) values as low as 20microM against several cancer lines, with an average value 54.4microM. "
04/01/2000 - "Dimethylformamide (DMF) has been suspected to associate with cancers in exposed workers, whereas there has been inadequate evidence for carcinogenicity in experimental animals. "
05/01/1989 - "A case-control study of cancer among du pont employees with potential for exposure to dimethylformamide."
02/15/1989 - "The anti-tumor activity of the putative differentiation-inducing agent dimethylformamide (DMF) was assessed in 7 head-and-neck xenograft (HNX) lines transplanted into nude mice. "
11/01/1985 - "In vitro effects of N,N-dimethylformamide on sublethal and potentially lethal damage recovery processes after X-irradiation in heterogeneous human colon tumor cells."