Dimethyl Suberimidate

The methyl imidoester of suberic acid used to produce cross links in proteins. Each end of the imidoester will react with an amino group in the protein molecule to form an amidine.

Also Known As:

Networked: 6 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Jin, Choong Eun: 1 article (01/2018)
2.	Koo, Bonhan: 1 article (01/2018)
3.	Lee, Eun Yeong: 1 article (01/2018)
4.	Liu, Huifang: 1 article (01/2018)
5.	Shin, Yong: 1 article (01/2018)
6.	Yun, Kyusik: 1 article (01/2018)
7.	Zhao, Fei: 1 article (01/2018)
8.	Zhong, Linlin: 1 article (01/2018)

Related Diseases

1.	Neoplasms (Cancer) 08/01/1980 - "The relative activity of rat IgE oligomers in eliciting secretion from mast cells and tumor basophils was examined using stable oligomers prepared by cross-linking IgE with dimethyl suberimidate. " 06/01/1982 - "Conformational changes of hexokinase from ascites tumor cells have been studied by chemical modification of lysine residues with imidoesters with the following results: 1) The membrane-bound enzyme, in contrast to the soluble enzyme, is not inactivated by treatment with dimethyl suberimidate, which suggests (a) lysine residue(s) essential for the activity that is protected in the membrane-bound enzyme. "
2.	Thrombasthenia (Glanzmann Thrombasthenia) 04/01/1996 - "Furthermore, the effect of HDL3 was abolished after covalent modification of HDL3 with dimethylsuberimidate and was not observed in platelets from Glanzmann thrombasthenia type 1 which do not express GP IIb/IIIa, as well as in platelets preincubated with anti-GP IIb/IIIa polyclonal antibodies. "
3.	Shock 05/01/1991 - "Twenty biopsies were fixed in dimethylsuberimidate and shock-frozen in slush nitrogen. "
4.	Rupture 01/01/2018 - "This binary nanomaterial couples a zinc oxide nanomultigonal shuttle (ZnO NMS) for cell membrane rupture without detergent and temperature control and diatomaceous earth with dimethyl suberimidate complex (DDS) for the capture and isolation of nucleic acids (NA) from cells. "
5.	Tick-Borne Encephalitis (Encephalitis, Tick Borne) 02/01/1980 - "Tick-borne encephalitis (TBE) virus was crosslinked by dimethylsuberimidate (DMS) and the cleavable dimetyl 3,3'-dithiobispropionimidate (DTBP). "

Related Drugs and Biologics

1.	Platelet Membrane Glycoprotein IIb
2.	Zinc Oxide
3.	Nucleic Acids
4.	Nitrogen
5.	Lysine (L-Lysine)
6.	Diatomaceous Earth (Kieselguhr)
7.	Imidoesters
8.	Immunoglobulin E (IgE)
9.	Hexokinase
10.	Enzymes