HOME PRODUCTS SERVICES COMPANY CONTACT FAQ

Dihydralazine

Subscribe to New Research on Dihydralazine

1,4-Dihydrazinophthalazine. An antihypertensive agent with actions and uses similar to those of HYDRALAZINE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p354)

Also Known As:

Altana Pharma Oranienburg Brand of Dihydralazine Sulfate; Depressan; Dihydralazine Sulfate; Dihydrallazine; Dihydrazinophthalazin; Sulfate, Dihydralazine; 1,4-Phthalazinedione, 2,3-dihydro-, dihydrazone

Networked: 159 relevant articles (5 outcomes, 14 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Heterocyclic Compounds: 60
- 1-Ring Heterocyclic Compounds
  - Pyridazines: 5
    - Phthalazines
      - Hydralazine: 1656
        Dihydralazine: 159
        reserpine drug combination dihydralazine: 5
        obsilazin: 2
        tri-torrat

Experts

1.	Hanff, Lidwien M: 1 article (06/2015)
2.	Steegers, Eric A: 1 article (06/2015)
3.	Edens, Mireille A: 1 article (06/2015)
4.	Vulto, Arnold G: 1 article (06/2015)
5.	Bijvank, Sebastiaan W Nij: 1 article (06/2015)
6.	Roofthooft, Danielle W: 1 article (06/2015)
7.	Duvekot, Johannes J: 1 article (06/2015)
8.	Visser, Willy: 1 article (06/2015)
9.	Schaefer, Sebastian: 1 article (01/2013)
10.	Gut, Nadezda: 1 article (01/2013)

Related Diseases

1.	Hypertension (High Blood Pressure) 02/01/1998 - "In many countries dihydralazine is considered the drug of choice for treating hypertension in pregnancy, because it now has been used safely for about 30 years, and the introduction of a new drug in pregnancy is a difficult task with partially unknown hazards. " 05/14/1993 - "Dihydralazine, which is used in the treatment of hypertension, causes a long-lasting hypotensive action by a direct vasodilator effect on arteriolar smooth muscle. " 03/01/1993 - " Intravenous dihydralazine is relatively safe for the rapid reduction of high blood pressure." 06/01/1987 - "Dihydralazine is widely used for acute control of hypertension. " 06/01/1986 - "The use of dihydralazine infusion in the management of severe hypertension in pregnancy."
2.	Hepatitis 01/01/1983 - "Hepatitis occurred during the administration of dihydralazine, quickly improved when the administration of dihydralazine was interrupted, and worsened again when it was resumed. " 10/01/1999 - "Dihydralazine is known to induce immunoallergic hepatitis. " 06/01/1990 - "A specific marker of dihydralazine-induced hepatitis." 01/01/1990 - "In patients with drug hepatitis after dihydralazine 15 out of 17 patients are genetically slow acetylators and they show also a lower activity of phase I cytochrom P-450 catalyzed biotransformation reactions. " 01/01/1990 - "[Dihydralazine hepatitis. "
3.	Heart Failure 10/01/1985 - "The action, efficient dosage and tolerance of a pure vasodilator, dihydralazine, used for the treatment of severe heart failure were studied in 30 children aged 1 month to 14 years. " 01/01/1985 - "Dihydralazine, sold under the name of Nepressol, is the derivative of the hydrazinophthalazines used in France for the treatment of severe cardiac failure. " 07/01/1984 - "According to these results, although patients with severe heart failure may show impressive haemodynamic improvement upon acute administration of dihydralazine, in most cases this improvement cannot be maintained under long-term therapy." 07/01/1984 - "Loss of effectiveness of dihydralazine in the long-term treatment of chronic heart failure." 01/01/1982 - "[Acute and chronic effects of dihydralazine in severe congestive heart failure at rest and during exercise (author's transl)]."
4.	Hyperemia 10/03/1980 - "These data indicate that a reduction in pulmonary and systemic-venous congestion due to chronic decompensated cardiac failure can be achieved with isosorbide dinitrate and prazosin, while cardiac output can be improved only with prazosin and dihydralazine."
5.	Pre-Eclampsia (Preeclampsia) 04/01/2004 - "The impact of maternal plasma volume expansion and antihypertensive treatment with intravenous dihydralazine on fetal and maternal hemodynamics during pre-eclampsia: a clinical, echo-Doppler and viscometric study." 04/01/2004 - "To establish the effects of plasma volume expansion (PVE) followed by intravenous dihydralazine (DH) administration on maternal whole blood viscosity (WBV) and hematocrit, uteroplacental and fetoplacental downstream impedance and umbilical venous (UV) volume flow in pre-eclampsia. " 01/01/1985 - "The hemodynamic effects of intravenously infused dihydralazine (incremental doses up to 125 micrograms per minute during 60 minutes) were studied in ten women with acute or superimposed severe preeclampsia. " 11/01/1977 - "[Continuous flow perfusion of dihydralazine during pregnancy toxemia. " 08/01/2006 - "Antihypertensive therapy in patients with pre-eclampsia: A prospective randomised multicentre study comparing dihydralazine with urapidil."

Related Drugs and Biologics

1.	urapidil
2.	Ketanserin
3.	Sulfamethazine (Sulfadimidine)
4.	Antipyrine (Phenazone)
5.	Captopril (Capoten)
6.	Clonidine (ST 155)
7.	Nifedipine (Adalat)
8.	Isosorbide Dinitrate (Isordil)
9.	Prazosin (Minipress)
10.	Diazoxide (Hyperstat)

Related Therapies and Procedures

1.	Resuscitation
2.	Surgical Instruments (Clip)
3.	Intravenous Injections
4.	Intravenous Infusions
5.	Catheters