Diethyl Pyrocarbonate (Diethylpyrocarbonate)

Preservative for wines, soft drinks, and fruit juices and a gentle esterifying agent.

Also Known As:

Diethylpyrocarbonate; Ethoxyformic Anhydride; Anhydride, Ethoxyformic; Dicarbonate, Diethyl; Oxydiformate, Diethyl; Pyrocarbonate, Diethyl; Diethyl Dicarbonate; Diethyl Oxydiformate; Pyrocarbonic Acid Diethyl Ester; Dicarbonic acid, diethyl ester

Networked: 22 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Carboxylic Acids: 973
  - Acyclic Acids
    - Formates: 7
      - Formic Acid Esters
        Diethyl Pyrocarbonate: 22
        dimethyl pyrocarbonate
        ethyl carbonate
        pyrocarbonic acid

Experts

1.	Da Poian, Andrea T: 2 articles (11/2007 - 01/2007)
2.	De Miranda, Joari: 2 articles (11/2007 - 01/2007)
3.	Schechter, Marcos C: 2 articles (11/2007 - 01/2007)
4.	Stauffer, Fausto: 2 articles (11/2007 - 01/2007)
5.	Cai, Qinghe: 1 article (12/2021)
6.	Cheng, Caitao: 1 article (12/2021)
7.	Feng, Yanqing: 1 article (12/2021)
8.	Feng, Yong: 1 article (12/2021)
9.	Guo, Peng: 1 article (12/2021)
10.	Ji, Lei: 1 article (12/2021)

Related Diseases

1.	Neuroblastoma 08/01/2001 - "The aim of this study was to explore and characterize the effect of the histidine-specific reagent diethylpyrocarbonate (DEPC) on the ERG (ether-à-go-go related gene) channels of whole-cell voltage-clamped NG108-15 neuroblastoma x glioma hybrid cells. "
2.	Glioma (Gliomas) 08/01/2001 - "The aim of this study was to explore and characterize the effect of the histidine-specific reagent diethylpyrocarbonate (DEPC) on the ERG (ether-à-go-go related gene) channels of whole-cell voltage-clamped NG108-15 neuroblastoma x glioma hybrid cells. "
3.	Vesicular Stomatitis 11/14/2007 - "We have demonstrated previously that modification of vesicular stomatitis virus (VSV) with diethylpyrocarbonate (DEPC) abolished the conformational changes on VSV glycoprotein and the fusion reaction induced by the virus. " 01/01/2007 - "We have demonstrated previously that modification of vesicular stomatitis virus (VSV) with diethylpyrocarbonate (DEPC) abolished conformational changes on VSV glycoprotein and the fusion reaction catalyzed by the virus. "
4.	Neoplasms (Cancer) 01/01/1980 - "Development of lung tumors can be observed in Kid: CFLP mice treated intragastrically with diethyl pyrocarbonate and ammonia. " 01/01/1980 - "The lung tumors may result from a carcinogenic substance, supposedly urethane, formed in vivo from diethyl pyrocarbonate in the presence of ammonia." 12/01/2021 - ": CCK-8: cell counting kit-8; CKAP2: Cytoskeleton associated protein 2; cDNA:complementary DNA; DAPI: 4',6-diamidino-2-phenylindole; DARS-AS1: DARS1 antisense RNA 1; DEPC: diethyl pyrocarbonate; DMEM-F12: Dulbecco's minimal essential medium/Ham's-F12; EMT: epithelial-mesenchymal transition; ERK: extracellular signal-regulated kinase; FAK: focal adhesion kinase; FBS: fetal bovine serum; GAPDH: glyceraldehyde-3-phosphate dehydrogenase; HCC: hepatocellular carcinoma; HE: hematoxylin-eosin; IHC: Immunohistochemistry; LIHC: Liver hepatocellular carcinoma; lncRNAs: long noncoding RNAs; MIAT: lncRNA myocardial infarction-related transcripts; MT: Mutant; NC: negative control; PBS: phosphate-buffered saline; PMSF: Phenylmethylsulfonyl fluoride; PVDF: polyvinylidene difluoride; RT: room temperature; RT-qPCR: real-time quantitative polymerase chain reaction; SDS-PAGE: sodium dodecyl sulfate-polyacrylamide gel electrophoresis; SPF: specific pathogen-free; TMAP: tumor-associated microtubule-associated protein; TUNEL: TdT-mediated dUTP nick end labeling; V: volume; WT: wild type."
5.	Hypersensitivity (Allergy) 08/11/1991 - "Site-specific intercalation at the triplex-duplex junction induces a conformational change which is detectable by hypersensitivity to diethylpyrocarbonate." 08/11/1991 - "Footprinting with diethylpyrocarbonate and dimethylsulphate revealed strong protection from modification of adenine residues within the triple-helix in concordance with their Hoogsteen pairing with the third strand, and a strong hypersensitivity to diethylpyrocarbonate at the first adenine of the duplex. " 04/11/1988 - "Binding of the bis-intercalators echinomycin and N,N'-di(9-acridinyl)spermidine or the mono-intercalators 9-aminoacridine and ethidium to DNA induces hypersensitivity of adenines towards reaction with diethyl pyrocarbonate. "

Related Drugs and Biologics

1.	Histidine (L-Histidine)
2.	Indicators and Reagents (Reagents)
3.	Ether (Diethyl Ether)
4.	Acids
5.	Sodium Dodecyl Sulfate (Sodium Lauryl Sulfate)
6.	Ligases (Synthetase)
7.	Glycoproteins (Glycoprotein)
8.	Glyceraldehyde-3-Phosphate Dehydrogenases (GAPD)
9.	Enzymes
10.	polyacrylamide