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Dicyclomine (Bentyl)

Subscribe to New Research on Dicyclomine

A muscarinic antagonist used as an antispasmodic and in urinary incontinence. It has little effect on glandular secretion or the cardiovascular system. It does have some local anesthetic properties and is used in gastrointestinal, biliary, and urinary tract spasms.

Also Known As:

Bentyl; Atlantis Brand of Dicyclomine Hydrochloride; Aventis Behring Brand of Dicyclomine Hydrochloride; Aventis Brand of Dicyclomine Hydrochloride; Bentylol; Di-Cyclonex; Di-Spaz; Dibent; Diclomin; Dicyclomine Hydrochloride; Florizel Brand of Dicyclomine Hydrochloride; Hauck Brand of Dicyclomine Hydrochloride; Hoechst Brand of Dicyclomine Hydrochloride; Lomine; Merbentyl; OR-Tyl; Ortega Brand of Dicyclomine Hydrochloride; Pasadena Brand of Dicyclomine Hydrochloride; Riva Brand of Dicyclomine Hydrochloride; Sigma Brand of Dicyclomine Hydrochloride; Spascol; Vangard Brand of Dicyclomine Hydrochloride; Vortech Brand of Dicyclomine Hydrochloride; Di Cyclonex; Di Spaz; Hydrochloride, Dicyclomine; OR Tyl; Dicycloverin; (1,1'-Bicyclohexyl)-1-carboxylic acid, 2-(diethylamino)ethyl ester

Networked: 65 relevant articles (8 outcomes, 3 trials/studies)

Relationship Network

Drug Context: Research Results

Organic Chemicals: 58
- Hydrocarbons: 412
  - Cyclic Hydrocarbons: 3
    - Alicyclic Hydrocarbons: 1
      - Cycloparaffins: 5
        Cyclohexanes: 2
        Dicyclomine: 65
        pyridoxine drug combination doxylamine dicyclomine: 48
- Carboxylic Acids: 83
  - Carbocyclic Acids
    - Cyclohexanecarboxylic Acids
      - Dicyclomine: 65
        pyridoxine drug combination doxylamine dicyclomine: 48

Experts

1.	Lembo, Anthony J: 2 articles (12/2015 - 07/2006)
2.	Dastidar, Sujata G: 2 articles (12/2004 - 11/2003)
3.	Nee, Judy: 1 article (12/2015)
4.	Zakari, Mohammed: 1 article (12/2015)
5.	Johnson, Jeremy D: 1 article (10/2015)
6.	Cocker, Katherine: 1 article (10/2015)
7.	Chang, Elisabeth: 1 article (10/2015)
8.	Sugumar, Ramya: 1 article (03/2013)
9.	Channaveera, Gokul Shetty: 1 article (03/2013)
10.	Mruthyunjaya, Shilpa: 1 article (03/2013)

Related Diseases

1.	Colic (Abdominal Cramps) 07/01/2006 - "While dicyclomine has been shown to be effective for colic, there are significant concerns about its safety, and the manufacturer has contraindicated its use in this population. " 06/01/1984 - "Dicyclomine eliminated colic in 15 of 24 (63%) infants, whereas placebo was effective in six of 24 (25%) (corrected X2 = 5.42, P = 0.02). " 01/19/1983 - "[Dicycloverin chloride solution--a remedy for severe infantile colic]." 01/01/2011 - "90 otherwise healthy 2-8 weeks old infants, born after gestational week 36, fulfilling the criteria for infantile colic and not medicated with dicyclomine, were included. " 07/01/2003 - "Dicyclomine hydrochloride is the only pharmacological treatment for infantile colic that has been consistently effective. "
2.	Abdominal Pain (Pain, Abdominal) 06/01/1981 - "It was concluded that over a 2-week period dicyclomine hydrochloride 40 mg 4 times a day is superior to placebo in improving the overall condition of the patient, decreasing abdominal pain, decreasing abdominal tenderness, and improving bowel habits. " 06/01/1981 - "During the 2-week double-blind study, the effects of dicyclomine hydrochloride compared to placebo were assesed by: 1) physicians' global evaluation of treatment, 2) patients' self-evaluation of treatment, and 3) patients' evaluation of duration of abdominal pain. " 07/01/2006 - "Dicyclomine and hyoscyamine, the two myorelaxants available in the United States, have not been proven effective in reducing abdominal pain in patients with IBS. " 05/01/1990 - "A randomised, double-blind study of mebeverine versus dicyclomine in the treatment of functional abdominal pain in young adults." 12/01/2015 - "Current treatments for diarrhea include mu-opioid agonists (i.e., loperamide, lomotil) and bile acid sequestrants (i.e., cholestyramine) while treatments for abdominal pain include antispasmodics (i.e., hyoscyamine, dicyclomine) and tricyclic antidepressants (i.e., amitriptyline). "
3.	Dyspepsia (Indigestion) 04/30/1988 - "Dicyclomine for idiopathic dyspepsia." 01/01/1984 - "Clearly patients like to take frequent treatment for dyspepsia, but symptom control is quite adequate if Merbentyl is given alone." 01/01/1984 - "Comparison of dicyclomine with antacid and without antacid in dyspepsia." 01/01/1984 - "In a study of forty-two patients with dyspepsia, hiatus hernia or duodenal ulcer, dicyclomine (Merbentyl) has been demonstrated to be effective in the control of the symptoms of this disorder. "
4.	Hernia (Hernias) 01/01/1984 - "In a study of forty-two patients with dyspepsia, hiatus hernia or duodenal ulcer, dicyclomine (Merbentyl) has been demonstrated to be effective in the control of the symptoms of this disorder. "
5.	Duodenal Ulcer (Curling's Ulcer) 01/01/1984 - "In a study of forty-two patients with dyspepsia, hiatus hernia or duodenal ulcer, dicyclomine (Merbentyl) has been demonstrated to be effective in the control of the symptoms of this disorder. "

Related Drugs and Biologics

1.	Dicyclomine (Bentyl)
2.	Pyridoxine (Pyridoxin)
3.	Doxylamine
4.	Atropine (Hyoscyamine)
5.	pyridoxine drug combination doxylamine dicyclomine (bendectin)
6.	Phenothiazines
7.	pyridoxine drug combination doxylamine
8.	oxybutynin (Tavor)
9.	Imipramine (Janimine)
10.	Scopolamine (Hyoscine)

Related Therapies and Procedures

1.	Therapeutics
2.	Aftercare (After-Treatment)