Dichloroethylenes

Toxic chlorinated unsaturated hydrocarbons. Include both the 1,1- and 1,2-dichloro isomers. Both isomers are toxic, but 1,1-dichloroethylene is the more potent CNS depressant and hepatotoxin. It is used in the manufacture of thermoplastic polymers.

Also Known As:

Chlorides, Vinylidene; Vinylidene Chlorides

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Halogenated Hydrocarbons: 42
    - Chlorinated Hydrocarbons: 240
      - Dichloroethylenes: 1
        vinylidene chloride: 40
        1,2-dichloroethylene: 3
        1,1-dichloroethylene epoxide: 1
        dichloroketene
  - Acyclic Hydrocarbons
    - Alkenes: 265
      - Ethylenes: 7
        Dichloroethylenes: 1
        vinylidene chloride: 40
        1,2-dichloroethylene: 3
        1,1-dichloroethylene epoxide: 1
        dichloroketene

Related Diseases

1.	Neural Tube Defects (Exencephaly) 05/01/1995 - "Odds ratios of > or = 1.50 were found for the following: total trihalomethanes with small for gestational age, central nervous system defects, oral cleft defects, and major cardiac defects; carbon tetrachloride with term low birth weight, small for gestational age, very low birth weight, total surveillance birth defects, central nervous system defects, neural tube defects, and oral cleft defects; trichloroethylene with central nervous system defects, neural tube defects, and oral cleft defects; tetrachloroethylene with oral cleft defects; total dichloroethylenes with central nervous system defects and oral cleft defects; benzene with neural tube defects and major cardiac defects; and 1,2-dichloroethane with major cardiac defects. "
2.	Congenital Abnormalities (Deformity) 05/01/1995 - "Odds ratios of > or = 1.50 were found for the following: total trihalomethanes with small for gestational age, central nervous system defects, oral cleft defects, and major cardiac defects; carbon tetrachloride with term low birth weight, small for gestational age, very low birth weight, total surveillance birth defects, central nervous system defects, neural tube defects, and oral cleft defects; trichloroethylene with central nervous system defects, neural tube defects, and oral cleft defects; tetrachloroethylene with oral cleft defects; total dichloroethylenes with central nervous system defects and oral cleft defects; benzene with neural tube defects and major cardiac defects; and 1,2-dichloroethane with major cardiac defects. "

Related Drugs and Biologics

1.	Trihalomethanes
2.	Trichloroethylene (Trichloroethene)
3.	Tetrachloroethylene (Tetrachloroethene)
4.	Carbon Tetrachloride (Tetrachloromethane)
5.	Benzene (Benzole)
6.	ethylene dichloride (1,2-dichloroethane)