Dibenzylchlorethamine

01/01/1949 - "Mechanism of dibenamine protection against cyclopropane-epinephrine cardiac arrhythmias."
04/01/1948 - "Protection against cyclopropane-epinephrine induced cardiac arrhythmias by dibenamine and other agents."
03/01/1948 - "Dibenamine protection against cyclopropane-epinephrine cardiac arrhythmias."

06/01/1974 - "Dibenamine: selective protection against diethylnitrosamine-induced hepatic carcinogenesis but not oral, pharyngeal and esophageal carcinogenesis."

11/01/1952 - "Effect of dibenamine on renal blood flow in hemorrhagic shock."
08/01/1950 - "Impending hemorrhagic shock and the course of events following administration of dibenamine."
01/01/1947 - "The effect of dibenamine on the production of irreversible hemorrhagic shock."
12/01/1989 - "The studies on the mechanism of action indicate that the ACTH-induced reversal of hemorrhagic shock (a) is an extra-hormonal, adrenal-independent effect, because it is not affected by adrenalectomy and is shared by many ACTH-fragments practically devoid of corticotropic activity; (b) is antagonized by morphine in a surmontable way; (c) needs the functional integrity of the sympathetic nervous system (it is prevented by guanethidine, reserpine, and clonidine) and the availability of peripheral alpha-adrenoceptors (it is antagonized by dibenamine, prazosin and yohimbine, but not by practolol); (d) requires the integrity of afferent vagal fibers (it is almost completely abolished by vagotomy); (e) involves central cholinergic networks (it is antagonized by atropine sulphate, but not by atropine methyl bromide; and it is prevented by the intracerebroventricular injection of hemicholinium-3); (f) is associated with a massive increase in the volume of circulating blood, likely due to a mobilization from peripheral pooling sites (it is largely prevented by splenectomy or by suprahepatic veins ligature, and is associated with a restoration of the venous blood flow in peripheral vascular beds and with a normalization of venous PO2); (g) is associated with a restoration of heart and spleen adrenoceptors, whose number is significantly decreased during hemorrhagic shock. "

01/01/1958 - "Effect of dibenamine on renal function in dogs with ischaemic shock."
01/01/1957 - "The effect of dibenamine given at different stages of ischaemic shock on survival time in dogs, and on the oedema of their ligated limbs."
10/01/1957 - "[Effects of dibenamine given at different stages of ischemic shock on the edema of the injured extremity and survival of dogs]."
10/01/1959 - "Finally the prevention by dibenamine of both the Shwartzman reaction and endotoxic shock and death in rabbits with a normal flora demonstrates that adrenergic activity plays an indispensable role in both phenomena. "
07/01/1979 - "Pretreatment of burn- and tourniquet-traumatized mice with propranolol (25 mg/kg) significantly decreased shock mortality, while pretreatment with dibenamine (25 mg/kg) significantly lowered early mortality after endotoxin. "

05/01/1952 - "The use of dibenamine in pheochromocytoma and detection of pressor activity of the plasma by bio-assay."
11/11/1948 - "The use of dibenamine in pheochromocytoma; report of a case."
01/01/2020 - "Phenoxybenzamine (used in pheochromocytoma) and dibenamine had two-component-binding inhibition curves at all three receptors. "
05/03/1951 - "The use of dibenamine and norepinephrine in the operative treatment of pheochromocytoma; report of two cases."
04/23/1949 - "For diagnosis, clinic and surgical therapy of the pheochromocytoma; Histamine test and dibenamine."