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Diatrizoate Meglumine (Gastrograffin)

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A versatile x-ray contrast medium for diagnostic radiology. It can be administered by most routes.

Also Known As:

Gastrograffin; Sinografin; Urovist; Amidotricoic Acid; Amidotrizoic Acid; Angiografin; Gastrografin; Gastrographin; Ioxeol; Meglumine Amidotrizoate; Reno 60; Reno M-Dip; Renograffin; Renografin; Renografin M-76; Triombrast; Triombrin; Urografin; Urografin 76; Verografin; Acid, Amidotricoic; Acid, Amidotrizoic; Amidotrizoate, Meglumine; Diatrizoate, Meglumine; Diatrizoate, Methylglucamine; Meglumine, Diatrizoate; Methylglucamine, Diatrizoate; Methylglucamine, Diatrizoic Acid; Reno M Dip; Reno MDip; Renografin M 76; Renografin M76; Diatrizoate Methylglucamine; Diatrizoic Acid Methylglucamine; Meglumine Diatrizoate; Methylglucamine Diatrizoate; D-Glucitol, 1-deoxy-1-(methylamino)-, 3,5-bis(acetylamino)-2,4,6-triiodobenzoate (salt)

Networked: 379 relevant articles (13 outcomes, 41 trials/studies)

Relationship Network

Drug Context: Research Results

Experts

1.	Weng, Te I: 2 articles (01/2013 - 04/2010)
2.	Bissett, I P: 2 articles (01/2007 - 01/2005)
3.	Parry, B R: 2 articles (01/2007 - 01/2005)
4.	Abbas, S: 2 articles (01/2007 - 01/2005)
5.	Pinto, Antonio: 2 articles (09/2006 - 03/2005)
6.	Romano, Luigia: 2 articles (09/2006 - 03/2005)
7.	Merola, Stefanella: 2 articles (09/2006 - 03/2005)
8.	Wang, H P: 2 articles (11/2001 - 07/2001)
9.	Chin, L W: 2 articles (11/2001 - 07/2001)
10.	Chen, W J: 2 articles (11/2001 - 07/2001)

Related Diseases

1.	Intestinal Obstruction (Obstruction, Intestinal) 11/01/2011 - "This study aims to determine the role of gastrografin in adhesive intestinal obstruction patients. " 01/01/2005 - "The search was conducted using MeSH terms: ''Intestinal obstruction'', ''water-soluble contrast'', "Adhesions" and "Gastrografin", and combined with the Cochrane Collaboration highly sensitive search strategy for identifying randomised controlled trials and controlled clinical trials. " 06/01/2013 - "A management protocol for adhesion intestinal obstruction with Gastrografin(®) is safe, reduces morbidity and mortality, and leads to a shorter hospital stay." 06/01/2013 - "All patients with adhesion intestinal obstruction without symptoms of strangulation were treated with Gastrografin(®), intravenous fluids and nasogastric tube. " 06/01/2013 - "To present a protocol to treat adhesion intestinal obstruction with Gastrografin(®) that is safe, and allows shorter hospital stays and shorter time between admission and surgery. "
2.	Cystic Fibrosis (Mucoviscidosis) 09/01/1973 - "The use of gastrografin in the relief of residual and late bowel obstruction in cystic fibrosis." 01/01/2007 - "Gastrograffin use orally or rectally may be helpful in the treatment of refractions distal intestinal obstruction syndrome in cystic fibrosis." 01/01/2007 - "Gastrograffin use in distal intestinal obstruction syndrome of cystic fibrosis." 10/01/1978 - "Two newborns with intestinal obstruction of the terminal ileum without mucoviscidosis were cured by Gastrografin enema. "
3.	Pain (Aches) 06/01/1996 - "Immediate postdilation parameters studies included: 1) severity of pain during dilation, 2) amount of blood on the dilator, 3) insufflation pressures during dilation, 4) esophageal emptying of gastrograffin (30 ml), and 5) esophageal emptying of barium sulfate (90 ml). " 12/01/1979 - "A second study showed no statistically significant difference in the incidence of pain between two groups of patients receiving either Renografin-45 (6% sodium diatrizoate, 39% meglumine diatrizoate) or Renografin-M-45 (45% meglumine diatrizoate)." 11/01/1984 - "Heat sensation in the Hexabrix group was distinctly lower than in those receiving Renografin, but the two groups did not differ with respect to average scores for pain. " 02/01/1983 - "Iohexol caused significantly less haemodynamic changes than Urografin and also the pain reactions were significantly reduced. " 12/01/1979 - "Four of 14 patients receiving meglumine diatrizoate experienced pain during venography, as compared to 14 of 17 patients receiving sodium diatrizoate (p less than 0.004). "
4.	Ileus 01/01/2016 - "The aim of this trial was to study the impact of oral Gastrografin(®) administration on postoperative prolonged ileus (PPI) after elective colorectal surgery. " 01/01/2016 - "A Double-Blinded Randomized Clinical Study on the Therapeutic Effect of Gastrografin(®) in Prolonged Postoperative Ileus After Elective Colorectal Surgery." 01/01/2016 - "Gastrografin(®) does not accelerate significantly the recovery of prolonged postoperative ileus after elective colorectal resection when compared with placebo. " 01/01/2016 - "We hypothesized that Gastrografin(®) may have therapeutic utility by accelerating the recovery of postoperative ileus after colorectal surgery. " 07/01/2015 - "To investigate the therapeutic value of Gastrografin in shortening duration of prolonged postoperative ileus (PPOI) after elective colorectal surgery. "
5.	Constipation 05/01/2002 - "Our results show that surfactant and Gastrografin are the most effective for the in vivo relief of constipation. " 05/01/2002 - "For relieving constipation in vivo, Gastrografin enema was most efficacious. " 12/01/2001 - "Symptoms included severe constipation (100%) and abdominal pain (84%); diagnostic workup included sitz marker study, anal manometry, and Gastrografin enema. "

Related Drugs and Biologics

1.	Diatrizoate Meglumine (Gastrograffin)
2.	Iopamidol (Isovue)
3.	Iohexol (Omnipaque)
4.	Vasodilator Agents (Vasodilators)
5.	Trypan Blue
6.	Povidone-Iodine (Betadine)
7.	iotrolan (Isovist)
8.	Diatrizoate (Hypaque)
9.	Barium
10.	Contrast Media

Related Therapies and Procedures

1.	Enema (Enemas)
2.	Decompression
3.	Prostatectomy (Retropubic Prostatectomy)
4.	Lymph Node Excision (Lymph Node Dissection)
5.	Oral Administration