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Deamino Arginine Vasopressin (Desmopressin)

Subscribe to New Research on Deamino Arginine Vasopressin

A synthetic analog of the pituitary hormone, ARGININE VASOPRESSIN. Its action is mediated by the VASOPRESSIN receptor V2. It has prolonged antidiuretic activity, but little pressor effects. It also modulates levels of circulating FACTOR VIII and VON WILLEBRAND FACTOR.

Also Known As:

Desmopressin; DDAVP; Desmopressin Acetate; Minirin; 1-Deamino-8-D-arginine Vasopressin; 1-Desamino-8-arginine Vasopressin; Adiuretin; Adiuretin SD; Apo-Desmopressin; Apotex Brand of Deamino Arginine Vasopressin; Desmogalen; Desmopressin Monoacetate; Desmopressin Monoacetate, Trihydrate; Desmopressine Ferring; Desmospray; Desmotabs; Ferring Brand 1 of Desmopressin Acetate; Ferring Brand 2 of Desmopressin Acetate; Galen Brand of Desmopressin Acetate; Hoyer Brand of Desmopressin Acetate; IQFA Brand of Desmopressin Acetate; Minurin; Nocutil; Norgine Brand of Desmopressin Acetate; Octim; Octostim; Acetate, Desmopressin; Arginine Vasopressin, Deamino; Ferring, Desmopressine; Monoacetate, Desmopressin; Monoacetate, Trihydrate Desmopressin; Trihydrate Desmopressin Monoacetate; Vasopressin, 1-Deamino-8-D-arginine; Vasopressin, 1-Desamino-8-arginine; Vasopressin, Deamino Arginine; Vasopressin, 1-(3-mercaptopropanoic acid)-8-D-arginine-

Networked: 1999 relevant articles (285 outcomes, 298 trials/studies)

Relationship Network

Drug Context: Research Results

Experts

1.	Federici, Augusto B: 17 articles (06/2014 - 02/2002)
2.	Federici, A B: 15 articles (01/2010 - 02/2000)
3.	Alonso, Daniel F: 14 articles (01/2015 - 09/2002)
4.	Franchini, Massimo: 14 articles (10/2013 - 06/2002)
5.	Nørgaard, Jens Peter: 13 articles (11/2015 - 10/2006)
6.	Eggert, Paul: 13 articles (08/2015 - 01/2002)
7.	Ripoll, Giselle V: 13 articles (01/2015 - 09/2002)
8.	Gomez, Daniel E: 12 articles (01/2015 - 09/2002)
9.	Mannucci, P M: 11 articles (08/2011 - 03/2000)
10.	Vande Walle, Johan: 10 articles (09/2015 - 09/2007)

Related Diseases

1.	Nocturnal Enuresis (Bedwetting) 07/01/2004 - "Alarms are the most effective treatment for nocturnal enuresis in children, but desmopressin may be considered for temporary relief." 07/01/1993 - "Seven of 10 children with nocturnal enuresis who receive desmopressin stop their bedwetting completely or reduce it significantly, with best results noted in children over 10 years of age. " 02/01/2008 - "In this issue Ferrara et al. present an important placebo-controlled, three-arm, double-blind, double-dummy, study on the treatment of nocturnal enuresis, demonstrating that homotoxicology is superior to placebo but less effective than desmopressin. " 07/01/2004 - "The study included 259 children suffering from PNE (92 girls, 167 boys, aged 5-18 years): 42 children were relieved from bedwetting after urotherapy and 136 children had a complete response to desmopressin. " 08/01/2015 - "Although desmopressin therapy is effective in treating polyuric monosymptomatic nocturnal enuresis (MNE), the relatively high rates of recurrence are problematic. "
2.	Hemorrhage 06/01/2010 - "Desmopressin was effective and safe in preventing significant bleeding at delivery in most of these patients." 05/01/2001 - "Using study-defined guidelines, patients evaluated the efficacy of high-dose DDAVP intranasal spray (1.5 mg mL(-1)) as 'excellent' or 'good' in 743 (95%) of 784 bleeding episodes. " 11/01/2015 - "After 1 dose of DDAVP, bleeding improved significantly and the recipient had an unremarkable recovery. " 01/01/2014 - "There was no significant reduction in bleeding for those who received DDAVP which questions the validity of this practice. " 01/01/2012 - "In conclusion, this review shows that DDAVP in selected cases is effective in reducing bleeding complications associated with pregnancy and childbirth with a good safety record. "
3.	Nocturia 12/01/2005 - "The mean frequency of nocturia was 6.1 before desmopressin and most (86%) patients had an improvement in nocturia within 1-12 weeks of treatment with desmopressin. " 05/01/1995 - "The purpose of the present study was to assess the efficacy of desmopressin in patients with PD with significant nocturia. " 01/01/2013 - "To compare efficacy of desmopressin for treatment of nocturia between patients with normal and high nocturnal bladder capacity index (NBCi). " 09/01/2013 - "Treatment with 50 μg desmopressin, the minimum effective dose, provided sustained improvement of nocturia throughout the study and meaningful benefits to patients with an improved safety profile." 09/01/2013 - "Previous studies suggest a lower dose of desmopressin orally disintegrating tablet may be effective in females compared to males with nocturia. "
4.	Polyuria 08/15/2008 - "Desmopressin is most effective in children with nocturnal polyuria and normal bladder capacity. " 09/01/1985 - "All patients had a significant reduction of their polyuria after a peroral dose of 50 micrograms DDAVP. " 11/01/2015 - "Desmopressin is an effective treatment for nocturnal polyuria in elderly women, where conservative treatment has failed. " 07/01/1999 - "Desmopressin is an effective treatment for nocturnal polyuria in some elderly men. " 07/01/1999 - "To assess whether desmopressin (1-desamino 8-d-arginine vasopressin) is safe and effective in the treatment of nocturnal polyuria in elderly men. "
5.	Enuresis 01/01/1999 - "The Swedish Enuresis Trial has produced some very positive results on the long-term use of desmopressin, showing a 61% response rate (> 50% reduction in wet nights). " 06/01/2004 - "Since antidiuretic treatment with desmopressin in the evening has proven effective against enuresis, it would not be surprising if diuretic treatment in the afternoon would have similar effects. " 03/01/1995 - "The efficacy of desmopressin in the treatment of functional enuresis, known for 15 years, has received very little attention in the psychiatric literature. " 12/01/2010 - "Following first line treatment 77.8% of the desmopressin group and 82% of the enuresis alarm group achieved a successful result, including full response in 37% and 50% of the groups, respectively (p=0.433). " 06/01/2012 - "Despite the small sample size of patients with ASD, our data show a favorable trend toward efficacy of desmopressin and anticholinergic therapy in these children with enuresis and DVS."

Related Drugs and Biologics

1.	Deamino Arginine Vasopressin (Desmopressin)
2.	Arginine Vasopressin (Argipressin)
3.	Vasopressins (Vasopressin)
4.	Factor VIII (Coagulation Factor VIII)
5.	Adrenocorticotropic Hormone (ACTH)
6.	Hormones
7.	oxybutynin (Tavor)
8.	Tablets
9.	von Willebrand Factor
10.	Diclofenac (SR 38)

Related Therapies and Procedures

1.	Intranasal Administration
2.	Drug Therapy (Chemotherapy)
3.	Coronary Artery Bypass (Coronary Artery Bypass Surgery)
4.	Intrauterine Devices (Intrauterine Device)
5.	Cardiopulmonary Bypass (Heart-Lung Bypass)