Dermoid Cyst (Dermoid)

A tumor consisting of displaced ectodermal structures along the lines of embryonic fusion, the wall being formed of epithelium-lined connective tissue, including skin appendages, and containing keratin, sebum, and hair. (Stedman, 25th ed)

Also Known As:

Networked: 621 relevant articles (25 outcomes, 24 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1.	Cysts
2.	Ovarian Cysts (Ovarian Cyst)
3.	Neoplasms (Cancer)
4.	Neurilemmoma (Schwannoma)
5.	Meningioma (Meningiomas)

Experts

1.	Morioka, Takato: 4 articles (01/2022 - 01/2007)
2.	Nakamura, Hiromi: 4 articles (10/2014 - 05/2005)
3.	Takeda, Akihiro: 4 articles (10/2014 - 05/2005)
4.	Shimogawa, Takafumi: 3 articles (01/2022 - 06/2016)
5.	Suzuki, Satoshi O: 3 articles (01/2022 - 06/2016)
6.	Kotarski, Jan: 3 articles (06/2015 - 08/2003)
7.	Polak, Grzegorz: 3 articles (06/2015 - 08/2003)
8.	Imoto, Sanae: 3 articles (10/2014 - 11/2010)
9.	Mukae, Nobutaka: 2 articles (01/2022 - 01/2020)
10.	Murakami, Nobuya: 2 articles (01/2022 - 01/2020)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Dermoid Cyst:

1.	Interleukin-6 (Interleukin 6)IBA 02/01/2012 - "To the best of our knowledge, this is the first study to provide evidence of IL-6 production by CD68(+) cells in a dermoid cyst involved in MCD." 02/01/2012 - "Immunohistochemical analysis of the tissue sections showed IL-6 production in CD68-positive macrophage cells, which had infiltrated the dermoid cyst. " 02/01/2012 - "Removal of the cyst resulted in partial improvement in systemic symptoms accompanied by a decrease in serum IL-6, while complete improvement was obtained by treatment with an anti-IL-6 receptor antibody following resection of the dermoid cyst. "
2.	Fibrin Tissue Adhesive (Fibrin Sealant)IBA 01/01/2023 - "To observe the clinical efficacy of the combined use of small incision lenticule extraction (SMILE)-derived lenticule patches in corneal dermoid excision, with fixation of the lenticule patches assisted by fibrin glue. " 01/01/2023 - "Treatment of corneal dermoid with lenticules from small incision lenticule extraction surgery: a surgery assisted by fibrin glue." 06/03/2016 - "Sutureless Lamellar Corneoscleral Patch Graft With Fibrin Sealant for Limbal Dermoid Removal." 11/01/2017 - "Combined interface tattooing and fibrin glue-assisted sutureless corneal resurfacing with donor lenticule obtained from small-incision lenticule extraction for limbal dermoid." 02/01/2011 - "Fibrin-glue assisted multilayered amniotic membrane transplantation in surgical management of pediatric corneal limbal dermoid: a novel approach."
3.	SiliconesIBA 09/01/2009 - "Bicanalicular silicone intubation at the beginning of surgery is helpful for the identification of the canaliculi and for the prevention of canalicular laceration during dermoid tumor excision."
4.	Bromodeoxyuridine (BrdU)IBA 09/01/1990 - "Both the BrdU-LI and the percentage of Ki-67 positive cells were significantly greater (P less than 0.005) in the group of clinically aggressive adult tumours, histologically identified as anaplastic astrocytomas and glioblastomas, than in the less aggressive ones (oligodendroglioma, meningiomas, schwannomas, pituitary adenomas, dermoid cyst) and in the cerebral metastatic localizations. "
5.	diazonaphthalenedisulfonic acid (NDS)IBA 01/01/2023 - "The study aimed to present the comparative analysis of midline congenital upper lip sinuses (MCULS) and nasal dermoids (NDs). " 10/01/2022 - "The study covered 24 surgically treated pediatric patients with nasal dermoids (NDs). " 08/29/2023 - "Developmental midline nasal masses including nasal dermoids (NDs), encephaloceles (EPHCs), and nasal glial heterotopias (NGHs) are a consequence of disrupted embryonal developmental processes in the frontonasal region. " 08/01/2011 - "Midline congenital lesions are rare and commonly comprise nasal dermoids (NDs), encephaloceles, and gliomas. "
6.	LipidsIBA 08/01/1986 - "[Electron microscopic study and lipid analysis of subcutaneous dermoid cyst]." 09/01/2020 - "Subconjunctival Lipid Leakage From Deep Orbital Dermoid Cysts." 07/01/2012 - "AIRP best cases in radiologic-pathologic correlation: Spinal conus dermoid cyst with lipid dissemination." 09/01/2011 - "Almost all intracranial dermoid cysts typically display low-density lesions on plain computerized tomography (CT) scans due to abundant lipids content. " 11/01/2003 - "Their most typical aspect is the presence of a low-density mass on CT, allowing an easy radiologic diagnosis of dermoid cyst containing lipids. "
7.	CholesterolIBA 01/01/1995 - "Surgical removal of the dermoid cyst which spilled cholesterol into the cavernous and intercavernous sinuses, allowed reduction of cholesterol levels in the postoperative period." 11/01/1998 - "Osseous changes in a cholesterol granuloma is better seen in CT scan, although MR imaging offers better differentiation from epidermoid or dermoid cysts and other subperiosteal process, as well as lacrimal fossa lesions. " 01/01/1995 - "Familial hypercholesterolemia and intracavernous venous spilling of cholesterol in a child with large suprasellar dermoid cyst. " 11/01/2010 - "Lumbar puncture revealed cholesterol crystals in the CSF and imaging studies revealed a sickle-shaped sacrum, partial rectal stenosis, and a communicating presacral meningocele with an epidermoid-dermoid mass. " 09/01/2007 - "There were two cases each of cholesterol granuloma, Langerhans' cell histiocytosis, and orbital dermoid. "
8.	Tumor Biomarkers (Tumor Markers)IBA 01/01/2012 - "Our study suggests that serum CA 19-9 is probably more accurate marker than other tumor markers in the ovarian dermoid cysts. " 01/01/2008 - "We suggest that besides ultrasonography and computed tomography, serum CA 19-9 level could be a useful tumor marker in the diagnosis of dermoid cysts." 01/01/2008 - "We found 43 cases of dermoid cysts that were operated on at our clinic, and whose tumor marker CA 19-9 was studied before the operation. " 01/01/2008 - "CA 19-9 can be a useful tumor marker in ovarian dermoid cysts." 05/01/1990 - "Clinical features of 174 pathologically confirmed dermoid cysts between Jan., 1985 and Aug., 1989 were reviewed, especially concerning tumor markers. "
9.	squamous cell carcinoma-related antigenIBA 10/01/2007 - "In line with the literature, our study highlights the importance of the age of the patient, the size of dermoid cyst and its growth rate as well as squamous cell carcinoma (SCC) antigen serum level. " 04/01/1998 - "In 4 cases of squamous cell carcinoma arising in a dermoid cyst and 22 cases of dermoid cyst, we studied tissue expressions and serum levels of squamous cell carcinoma antigen (SCC), CA 19-9 and CA 125, and the mutation of the p53 tumor suppressor gene. " 05/01/2023 - "Patients with ruptured cysts had significantly higher serum C-reactive protein (CRP), cancer antigen 125 (CA125), carbohydrate antigen 19-9 (CA19-9), and squamous cell carcinoma antigen (SCC) levels compared with patients with uncomplicated dermoid cysts or cysts with torsion. "
10.	Testosterone (Sustanon)FDA Link 06/01/2009 - "The dermoid was producing large amounts of testosterone from a nest of Leydig cells found pathologically in the mass. " 06/01/2009 - "In fact, there are no reported cases of virilization from a testosterone-producing ovarian dermoid in the adolescent female age group. " 08/01/1978 - "Ovarian vein catheterization studies revealed bilateral excess plasma testosterone and androstenedione secretion, and at surgery multiple dermoid cysts of both ovaries were found in association with polycystic ovaries. "

Therapies and Procedures

1.	Cystectomy 11/01/2020 - "There is a lack of consensus among gynaecologists regarding the optimal surgical treatment modalities for ovarian dermoid cysts; however, laparoscopic cystectomy is the gold standard for the surgical treatment of dermoid cysts. " 01/01/2021 - "Laparoscopic single-site "in-bag" ovarian dermoid cystectomy is feasible, effective, and safe in pregnant patients with a large adnexal mass. " 12/01/2009 - "Laparoscopic cystectomy is a safe and effective method of managing ovarian dermoid cysts in the pediatric and adolescent patient population." 05/01/1996 - "We compared the efficacy of two dissection methods of ovarian dermoid laparoscopic cystectomy in 41 women (age 17-38 yrs) who desired future fertility. " 09/01/1995 - "The safety and efficacy of laparoscopic ovarian dermoid cystectomy were evaluated in 40 women. "
2.	Laparotomy 09/01/1999 - "Laparoscopy is safe and effective for dermoid cysts and allows shorter hospitalization than laparotomy. " 12/01/1996 - "The aim of our study was to compare laparoscopy with laparotomy for the removal of ovarian dermoid cysts. " 11/01/2022 - "Laparoscopy versus laparotomy for pediatric ovarian dermoid." 06/01/2022 - "Laparoscopy versus laparotomy for pediatric ovarian dermoids." 06/01/2021 - "After laparotomy and open surgery transit through a left vertical incision, the histopathologic examination revealed a retroperitoneal dermoid cyst. "
3.	Corneal Transplantation (Keratoplasty) 01/01/2002 - "Excision with lamellar keratoplasty appears to be an effective means of management for extensive limbal dermoid. " 01/01/2019 - "To evaluate the safety and efficacy of lamellar keratoplasty using preserved donor corneas to treat limbal dermoids. " 01/01/2023 - "Herein, we present a case of deep limbal dermoid treated with surgical resection and lamellar keratoplasty using microkeratome-assisted anterior lamellar graft." 01/01/2023 - "Lamellar Keratoplasty Using Microkeratome-Assisted Anterior Lamellar Graft in the Management of Deep Limbal Dermoid: A Case Report." 07/01/2021 - "Limbal dermoid excision and lamellar keratoplasty were performed in the left eye and followed by a simple excision of the limbal dermoid in the right eye. "
4.	Tattooing 06/01/2015 - "To evaluate the efficacy of combined surgery of simple excision, corneal tattooing, and a sutureless limboconjunctival autograft in pediatric patients with grade 1 limbal dermoids. " 01/01/2013 - "To evaluate and report the efficacy of combined surgical excision and corneal tattooing in patients with limbal dermoids. " 01/01/2023 - "Based on the results of this study, our innovative surgical method which includes complete excision with corneal tattooing and limbal conjunctival autograft can be a simple and safe procedure that achieves long standing cosmesis with limbal dermoids." 01/01/2023 - "All patients who were referred to our clinic for limbal dermoid, and underwent a combined surgery of complete excision, corneal tattooing, and a sutureless limbal conjunctival autograft were retrospectively reviewed. " 01/01/2023 - "To report a long-term outcome of the novel combined surgical method of complete excision, corneal tattooing, and a sutureless limbal conjunctival autograft for limbal dermoid. "
5.	Transplantation 01/01/2023 - "Seventeen eyes of 17 patients with corneal dermoid were treated with dermoid removal combined with SMILE-derived lenticule transplantation. " 12/01/2020 - "To report the surgical management of extensive epibulbar dermoids with autologous oral mucous membrane transplantation. " 12/01/2020 - "Surgical management of large bilateral epibulbar dermoids with autologous oral mucous membrane transplantation." 11/01/2018 - "Here we report a rare case of progressive, large pediatric corneal limbal dermoid in a newborn, managed with tissue glue-assisted monolayer amniotic membrane transplantation. " 11/01/2018 - "Progressive large pediatric corneal limbal dermoid management with tissue glue-assisted monolayer amniotic membrane transplantation: A case report."