Dermoid Cyst (Dermoid)

A tumor consisting of displaced ectodermal structures along the lines of embryonic fusion, the wall being formed of epithelium-lined connective tissue, including skin appendages, and containing keratin, sebum, and hair. (Stedman, 25th ed)

Also Known As:

Networked: 467 relevant articles (18 outcomes, 15 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1.	Ovarian Cysts (Ovarian Cyst)
2.	Neoplasms (Cancer)
3.	Cysts
4.	Meningioma (Meningiomas)
5.	Pituitary Neoplasms (Pituitary Adenoma)

Experts

1.	Nakamura, Hiromi: 4 articles (10/2014 - 05/2005)
2.	Takeda, Akihiro: 4 articles (10/2014 - 05/2005)
3.	Polak, Grzegorz: 3 articles (06/2015 - 08/2003)
4.	Kotarski, Jan: 3 articles (06/2015 - 08/2003)
5.	Imoto, Sanae: 3 articles (10/2014 - 11/2010)
6.	Barczyński, Bartłomiej: 2 articles (06/2015 - 01/2013)
7.	Bednarek, Wiesława: 2 articles (06/2015 - 01/2013)
8.	Kwon, Ji-Won: 2 articles (06/2015 - 01/2013)
9.	Kwaśniewski, Wojciech: 2 articles (06/2015 - 01/2013)
10.	Derewianka-Polak, Magdalena: 2 articles (06/2015 - 01/2013)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Dermoid Cyst:

1.	Interleukin-6 (Interleukin 6)IBA 02/01/2012 - "To the best of our knowledge, this is the first study to provide evidence of IL-6 production by CD68(+) cells in a dermoid cyst involved in MCD." 02/01/2012 - "Immunohistochemical analysis of the tissue sections showed IL-6 production in CD68-positive macrophage cells, which had infiltrated the dermoid cyst. " 02/01/2012 - "Removal of the cyst resulted in partial improvement in systemic symptoms accompanied by a decrease in serum IL-6, while complete improvement was obtained by treatment with an anti-IL-6 receptor antibody following resection of the dermoid cyst. "
2.	SiliconesIBA 09/01/2009 - "Bicanalicular silicone intubation at the beginning of surgery is helpful for the identification of the canaliculi and for the prevention of canalicular laceration during dermoid tumor excision."
3.	Bromodeoxyuridine (BrdU)IBA 09/01/1990 - "Both the BrdU-LI and the percentage of Ki-67 positive cells were significantly greater (P less than 0.005) in the group of clinically aggressive adult tumours, histologically identified as anaplastic astrocytomas and glioblastomas, than in the less aggressive ones (oligodendroglioma, meningiomas, schwannomas, pituitary adenomas, dermoid cyst) and in the cerebral metastatic localizations. "
4.	CholesterolIBA 01/01/1995 - "Surgical removal of the dermoid cyst which spilled cholesterol into the cavernous and intercavernous sinuses, allowed reduction of cholesterol levels in the postoperative period." 11/01/1998 - "Osseous changes in a cholesterol granuloma is better seen in CT scan, although MR imaging offers better differentiation from epidermoid or dermoid cysts and other subperiosteal process, as well as lacrimal fossa lesions. " 01/01/1995 - "Familial hypercholesterolemia and intracavernous venous spilling of cholesterol in a child with large suprasellar dermoid cyst. " 11/01/2010 - "Lumbar puncture revealed cholesterol crystals in the CSF and imaging studies revealed a sickle-shaped sacrum, partial rectal stenosis, and a communicating presacral meningocele with an epidermoid-dermoid mass. " 09/01/2007 - "There were two cases each of cholesterol granuloma, Langerhans' cell histiocytosis, and orbital dermoid. "
5.	Biological Tumor Markers (Tumor Markers)IBA 01/01/2012 - "Our study suggests that serum CA 19-9 is probably more accurate marker than other tumor markers in the ovarian dermoid cysts. " 05/01/1990 - "Clinical features of 174 pathologically confirmed dermoid cysts between Jan., 1985 and Aug., 1989 were reviewed, especially concerning tumor markers. " 01/01/2012 - "Tumor markers panel and tumor size of ovarian dermoid tumors in reproductive age." 01/01/2008 - "Squamous cell carcinomas originating from dermoid cysts are rare tumors especially seen in elderly patients with high levels of tumor markers (like CEA, SCCA). " 03/01/2008 - "To exclude malignancy and metastatising of dermoid cyst the determination of tumor markers (alpha-phetoprotein, beta-chorionic gonadotropin content) is indicated."
6.	papillary Thyroid cancerIBA 09/01/2012 - "Follicular variant of papillary thyroid carcinoma arising from a dermoid cyst: a rare malignancy in young women and review of the literature." 01/01/2013 - "Ovarian dermoid cyst serendipitously detected by pelvic radioiodine-(131)I uptake and by diffusion weighted MRI in a post-thyroidectomy case of papillary thyroid carcinoma." 08/18/2015 - "She was previously diagnosed with left ovarian dermoid cyst, right posterior mediastinal neurilemmoma, left forearm neurilemmoma, and papillary thyroid carcinoma, underwent operation treatment. " 12/01/2011 - "This study reports 3 unusual cases of malignant transformation in mature cystic teratoma of the ovary (dermoid cyst), namely carcinosarcoma, atypical choroid plexus papilloma, and papillary thyroid carcinoma, the last case involving both ovaries and with peritoneal dissemination. "
7.	Testosterone (Sustanon)FDA Link 06/01/2009 - "The dermoid was producing large amounts of testosterone from a nest of Leydig cells found pathologically in the mass. " 06/01/2009 - "In fact, there are no reported cases of virilization from a testosterone-producing ovarian dermoid in the adolescent female age group. " 08/01/1978 - "Ovarian vein catheterization studies revealed bilateral excess plasma testosterone and androstenedione secretion, and at surgery multiple dermoid cysts of both ovaries were found in association with polycystic ovaries. "
8.	antineoplaston A10 (A 10)IBA 05/01/1998 - "In the 55 women, 58 dermoid cysts (mean diameter 5.6 +/- 2.03 cm) were enucleated and removed at operative laparoscopy through a 10- to 12-mm cannula sleeve without intraoperative or postoperative complications. " 05/01/1998 - "Patients were randomly assigned to removal of dermoid cysts from the abdominal cavity with or without an endobag through a 10- to 12-mm cannula sleeve. " 07/01/2013 - "This is a case-report study for evaluation a couple with male factor infertility, who was a good candidate for intracytoplasmic sperm injection (ICSI), while a 10 cm dermoid cyst was found in the woman's right ovary. "
9.	squamous cell carcinoma-related antigenIBA 10/01/2007 - "In line with the literature, our study highlights the importance of the age of the patient, the size of dermoid cyst and its growth rate as well as squamous cell carcinoma (SCC) antigen serum level. " 04/01/1998 - "In 4 cases of squamous cell carcinoma arising in a dermoid cyst and 22 cases of dermoid cyst, we studied tissue expressions and serum levels of squamous cell carcinoma antigen (SCC), CA 19-9 and CA 125, and the mutation of the p53 tumor suppressor gene. "
10.	Transcription Factors (Transcription Factor)IBA 01/01/2012 - "To study clinical features and gene mutations within the paired-like homeodomain transcription factor 2 (PITX2) gene in a pedigree of bilateral limbal dermoids. "

Therapies and Procedures

1.	Laparotomy 09/01/1999 - "Laparoscopy is safe and effective for dermoid cysts and allows shorter hospitalization than laparotomy. " 12/01/1996 - "The aim of our study was to compare laparoscopy with laparotomy for the removal of ovarian dermoid cysts. " 11/01/2011 - "Experienced laparoscopic surgeons should consider laparoscopy as an alternative to laparotomy in management of ovarian dermoid cysts in selected cases. " 12/01/2010 - "In 1999, at the age of 18, the patient had undergone enucleation of a dermoid cyst of the left ovary by laparotomy and a segment of the right ovary had been collected. " 07/01/2008 - "Cystoscopic evaluation followed by laparotomy and excision of ovarian dermoid along its extension to the urinary bladder is a rational approach. "
2.	Cystectomy 12/01/2009 - "Laparoscopic cystectomy is a safe and effective method of managing ovarian dermoid cysts in the pediatric and adolescent patient population." 05/01/1996 - "We compared the efficacy of two dissection methods of ovarian dermoid laparoscopic cystectomy in 41 women (age 17-38 yrs) who desired future fertility. " 09/01/1995 - "The safety and efficacy of laparoscopic ovarian dermoid cystectomy were evaluated in 40 women. " 04/01/2014 - "In the later part of our study we performed laparoscopic cystectomy and ovarian preservation in 40 cases, including 7 cases of dermoid, where we performed laparoscopic detorsion with dermoid cystectomy and ovarian preservation in the same sitting. " 11/01/2012 - "Laparoscopic dermoid cystectomy performed by mesial incision (33 patients, study group) or antimesial incision (34 patients, control group). "
3.	Tattooing 06/01/2015 - "To evaluate the efficacy of combined surgery of simple excision, corneal tattooing, and a sutureless limboconjunctival autograft in pediatric patients with grade 1 limbal dermoids. " 01/01/2013 - "To evaluate and report the efficacy of combined surgical excision and corneal tattooing in patients with limbal dermoids. " 01/01/2013 - "Simple keratectomy and corneal tattooing for limbal dermoids: results of a 3-year study." 06/01/2015 - "We treated 4 eyes of 4 patients with combined surgery of corneal tattooing and a sutureless limboconjunctival autograft with simple excision of limbal dermoids. " 06/01/2015 - "New surgical approach for limbal dermoids in children: simple excision, corneal tattooing, and sutureless limboconjunctival autograft."
4.	Rhinoplasty 05/01/2010 - "To assess the efficacy of excision of nasal dermoids through a closed rhinoplasty incision. " 01/01/2015 - "The remaining 32 patients had dermoids excised with an open approach (direct, bicoronal, or rhinoplasty). " 11/01/2010 - "The endoscopic-assisted, closed rhinoplasty approach allows for safe and complete excision of uncomplicated nasoglabellar dermoid cysts. " 11/01/2010 - "Patients with nasoglabellar dermoid cysts without intracranial communication were treated with the endoscopic-assisted, closed rhinoplasty approach. " 11/01/2010 - "Endoscopic-assisted, closed rhinoplasty approach for excision of nasoglabellar dermoid cysts."
5.	Ovariectomy (Oophorectomy) 08/01/2012 - "Early tumour removal is associated with an improved prognosis and a laparoscopic oophorectomy was performed following detection of a dermoid cyst. " 03/01/2015 - "Ovariectomy due to a dermoid cyst in an orangutan (Pongo pygmaeus)." 10/01/2007 - "Right salpingo-oophorectomy was performed with the histologic diagnosis of dermoid cyst. " 12/01/2006 - "Dermoid cyst enucleation was the most commonly applied procedure, while oophorectomy was the least frequent. " 05/01/2005 - "Because the symptom is nonspecific, the clinical features were confusing, especially in emergency cases; in two patients with adnexal torsion with dermoid cysts and one patient with adnexal torsion of a normal ovary, there was substantial delay in diagnosis, and salpingo-oophorectomy was required as a result. "