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Dentin Sensitivity

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Also Known As:

Dentine Hypersensitivity; Dentine Sensitivity; Dentin Hypersensitivities; Dentin Sensitivities; Dentine Hypersensitivities; Dentine Sensitivities; Hypersensitivities, Dentin; Hypersensitivities, Dentine; Hypersensitivity, Dentin; Hypersensitivity, Dentine; Sensitivities, Dentin; Sensitivities, Dentine; Sensitivity, Dentin; Sensitivity, Dentine; Dentin Hypersensitivity

Networked: 384 relevant articles (110 outcomes, 132 trials/studies)

Relationship Network

Disease Context: Research Results

Stomatognathic Diseases: 372
- Tooth Diseases: 15
  - Dentin Sensitivity: 384

Related Diseases

1.	Pain (Aches)
2.	Gingival Recession
3.	Dental Caries (White Spot)
4.	Hypersensitivity (Allergy)
5.	Calculi (Calculus)

Experts

1.	DeVizio, William: 13 articles (04/2013 - 01/2009)
2.	Mateo, Luis R: 12 articles (04/2013 - 01/2009)
3.	Zhang, Yun Po: 10 articles (03/2013 - 01/2009)
4.	DeVizio, W: 10 articles (01/2012 - 06/2000)
5.	Cummins, D: 9 articles (01/2011 - 01/2009)
6.	Ishikawa, Kunio: 7 articles (01/2010 - 08/2002)
7.	Kawasaki, Akiko: 7 articles (01/2010 - 08/2002)
8.	Ebisu, Shigeyuki: 7 articles (01/2010 - 08/2002)
9.	Matsuo, Takashi: 7 articles (01/2010 - 08/2002)
10.	Suge, Toshiyuki: 7 articles (01/2010 - 08/2002)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Dentin Sensitivity:

1.	Arginine (L-Arginine)FDA Link 03/01/2013 - "The results of this study support the conclusion that the Arginine Mouthwash provides a significant reduction in dentin hypersensitivity after eight weeks of product use as compared to a Negative Control mouthwash." 03/01/2013 - "The efficacy of 8% Arginine-CaCO₃ applications on dentine hypersensitivity following periodontal therapy: a clinical and scanning electron microscopic study." 10/01/2014 - "8% Arginine paste was found to be more effective than Gluma desensitizer in providing immediate relief from dentine hypersensitivity and also sustained the effect significantly for a period of 30 days. " 10/01/2013 - "Arginine-containing toothpastes are a promising new treatment for dentin hypersensitivity (DH), which afflicts a considerable number of patients. " 05/01/2013 - "The aim of this study was to evaluate the clinical efficacy of an in-office desensitizing paste containing 8% arginine and calcium carbonate relative to calcium carbonate alone in the reduction of dentin hypersensitivity in a randomized, double-blind, split-mouth clinical trial. "
2.	ToothpastesIBA 05/01/2010 - "This clinical study demonstrated that the new Pro-Argin formula toothpaste provided a significant reduction in dentin hypersensitivity when used over a period of 8 weeks. " 12/01/2013 - "Study suggests dentine bonding agents provided better relief from dentine hypersensitivity than a desensitising toothpaste." 01/01/2005 - "This study demonstrated that the new toothpaste was effective in reducing dentine hypersensitivity. " 12/01/2011 - "As the innovative bioactive glass-containing toothpaste occlude dentinal tubules and resist acid challenge, it may be useful for the treatment of dentine hypersensitivity and dentine remineralization." 02/01/2013 - "A 3-day randomised clinical study investigating the efficacy of two toothpastes, designed to occlude dentine tubules, for the treatment of dentine hypersensitivity."
3.	Dentifrices (Dentifrice)IBA 12/01/1984 - "There was a difference in the time it took the dentifrices to achieve a statistically significant reduction in dentin sensitivity." 06/01/2010 - "Several dentifrices have shown to be effective in reducing dentine hypersensitivity (DH), but more effective products are needed. " 09/01/2010 - "To assess the efficacy of a novel stannous-containing dentifrice in the reduction of dentin hypersensitivity when compared to a marketed positive control dentifrice. " 05/01/2013 - "Measurement of dentin hypersensitivity with the Jay Sensitivity Sensor Probe and the Yeaple probe to compare relief from dentin hypersensitivity by dentifrices." 05/01/2013 - "A comparison of dentifrices for clinical relief from dentin hypersensitivity using the Jay Sensitivity Sensor Probe."
4.	Calcium Carbonate (Limestone)FDA Link 05/01/2013 - "The aim of this study was to evaluate the clinical efficacy of an in-office desensitizing paste containing 8% arginine and calcium carbonate relative to calcium carbonate alone in the reduction of dentin hypersensitivity in a randomized, double-blind, split-mouth clinical trial. " 02/01/2015 - "Efficacy of a combined in-office/home-use desensitizing system containing 8% arginine and calcium carbonate in reducing dentin hypersensitivity: an 8-week randomized clinical study." 06/01/2012 - "To evaluate the clinical efficacy of a professional prophylaxis paste containing 8% arginine-calcium carbonate in the reduction of dentin hypersensitivity used as a pre-procedural application compared to a commercially-available prophylaxis paste. " 06/01/2012 - "This paper provides an overview of the etiology of dentin hypersensitivity, the discovery and development of measures for combating the problem, and the available data on the clinical efficacy of products based on 8% arginine and calcium carbonate." 03/01/2009 - "Clinical evaluation of the efficacy of an in-office desensitizing paste containing 8% arginine and calcium carbonate in providing instant and lasting relief of dentin hypersensitivity."
5.	FluoridesIBA 02/01/1978 - "It was concluded that topical applications of fluoride are modestly effective for treatment of dentin hypersensitivity, but the most rapid and effective relief follows fluoride iontophoresis. " 10/01/2004 - "Dentine hypersensitivity: a randomised, double-blind placebo-controlled study of the efficacy of a fluoride-sensitive teeth mouthrinse." 06/01/2013 - "Clinical evaluation of the efficacy of fluoride adhesive tape (F-PVA) in reducing dentin hypersensitivity." 07/01/2006 - "Treating cervical dentin hypersensitivity with fluoride varnish: a randomized clinical study." 01/01/2016 - "And with their ability to release fluoride locally, FBGs make interesting candidates for various clinical applications, dentinal tubule occlusion in the treatment of dentin hypersensitivity. "
6.	Sodium Fluoride (Ossin)FDA Link 05/01/2012 - "It was concluded that all the desensitizing agents were capable of reducing dentin hypersensitivity, with the exception of the placebo and the sodium fluoride groups." 09/01/1979 - "[Clinical effects of topical application of F-Varnish and 2% sodium fluoride solution in dentin sensitivity]." 11/01/1945 - "Sodium fluoride therapy for combating dentin sensitivity and gingival decay." 07/01/2005 - "The aim of the present study was to evaluate clinically and under scanning electron microscopy (SEM) the efficacy of Nd:YAG laser irradiation alone and in combination with 5% sodium fluoride varnish in the management of dentin hypersensitivity. " 07/01/2005 - "The number of patent tubules also progressively decreased from group 1 through group 4. The combination of Nd:YAG laser and 5% sodium fluoride varnish seems to show an impressive efficacy, when compared to either treatment alone, in treating dentin hypersensitivity. "
7.	fluorophosphate (sodium monofluorophosphate)FDA Link 02/18/2011 - "The dentine hypersensitivity was evaluated by a subject self-perceived short, sharp pain in visual analogue scale (VAS) in response to a blast of cold air from a triple syringe administered to a tooth surface in 1 cm. Test toothpastes, containing 5.53% potassium citrate and 0.76% sodium monofluorophosphate, and control toothpastes, containing only 0.76% sodium monofluorophosphate were delivered to the study subjects in the test and control group respectively. " 08/01/2015 - "To compare the efficacy of an anhydrous dentifrice containing 0.454% w/w stannous fluoride and a negative control dentifrice containing 1,000 ppm fluoride, as sodium monofluorophosphate, at reducing dentin hypersensitivity over 8 weeks with twice-daily brushing. " 03/01/2013 - "To compare the efficacy of a 0.454% w/w stannous fluoride containing anhydrous dentifrice and a negative control dentifrice containing 1,000 ppm fluoride (as sodium monofluorophosphate) at reducing dentin hypersensitivity over an 8-week period, following twice daily brushing. " 01/01/2005 - "The purpose of this study was to investigate the effect of a new toothpaste containing an antiplaque and antiinflammatory agent (0.3% triclosan), a desensitizing agent (5% potassium nitrate) and an anticaries agent (0.76% sodium monofluorophosphate (SMFP)) on gingival health, plaque formation and dentine hypersensitivity in a 12-week home study. " 05/01/2010 - "To present the results of an 8-week dentin hypersensitivity clinical study in which the efficacy of a new Pro-Argin formula toothpaste, with gentle whitening benefits, containing 8.0% arginine, a high cleaning calcium carbonate system, and 1450 ppm fluoride as sodium monofluorophosphate (MFP) was compared to that of a commercial Pro-Argin formula toothpaste containing 8.0% arginine, calcium carbonate, and 1450 ppm fluoride as MFP and a negative control toothpaste containing calcium carbonate and 1450 ppm fluoride as MFP. "
8.	PotassiumIBA 01/01/2000 - "The efficacy of potassium salts as agents for treating dentin hypersensitivity." 01/01/2006 - "Randomised controlled trials (RCTs) in which the effect on dentine hypersensitivity of potassium containing toothpastes was tested against non-potassium containing control toothpastes. " 01/01/2015 - "Dentin hypersensitivity is treated using materials that occlude the dentinal tubules or release potassium ions that induce nerve desensitization. " 03/01/2013 - "Arginine regimen provided the greatest reduction in Tactile and Air-Blast dentine hypersensitivity compared to potassium and negative control regimens; and provides faster dentine hypersensitivity relief than potassium regimen." 07/01/2007 - "Effects of potassium ions on dentine sensitivity in man."
9.	potassium nitrate (saltpeter)IBA 11/01/1996 - "Efficacy of a potassium nitrate mouthwash in alleviating cervical dentine sensitivity (CDS)." 01/01/2001 - "No strong evidence is available supporting the efficacy of potassium nitrate toothpaste for dentine hypersensitivity." 04/01/2003 - "Evaluation of the efficacy of two potassium nitrate bioadhesive gels (5% and 10%) in the treatment of dentine hypersensitivity. " 05/01/2013 - "The aim of this randomized controlled clinical trial was to investigate the effect of a new Iranian toothpaste and a commercially available toothpaste containing desensitizing agent (5% potassium nitrate) on dentine hypersensitivity in a 24-week study. " 01/01/2001 - "Randomised clinical trials (RCTs) in which the effect on dentine hypersensitivity of potassium nitrate toothpastes were tested against non-potassium nitrate containing placebo toothpastes. "
10.	Silicon Dioxide (Sand)FDA LinkGeneric 07/01/2011 - "To evaluate the laboratory dentin occlusion efficacy and effects on dentin permeability of a new multi-benefit dentifrice in order to gain insight into the mechanism of action of a novel technology for dentin hypersensitivity relief based on a specially-designed silica and copolymer system. " 01/01/2009 - "The study also showed that this new arginine toothpaste provided significantly greater reductions (p < 0.05) in dentin hypersensitivity in response to tactile (16.2%, 22.4%, and 21.4%) and air blast (16.2%, 29.2%, and 63.4%) stimuli than the benchmark commercial toothpaste containing 2% potassium ion and 1450 ppm NaF in a silica base, after two, four, and eight weeks of product use, respectively. " 01/01/2010 - "A comparative clinical study investigating the efficacy of a dentifrice containing 8% strontium acetate and 1040 ppm fluoride in a silica base and a control dentifrice containing 1450 ppm fluoride in a silica base to provide immediate relief of dentin hypersensitivity." 01/01/2011 - "The test toothpaste containing 8% strontium acetate and 1040 ppm fluoride as NaF in a silica base, when used for a single topical application and twice-daily brushing for seven days, does not provide statistically significant relief of dentin hypersensitivity compared to a negative control toothpaste containing 1100 ppm fluoride as NaF in a silica base. " 01/01/2009 - "The study also showed that the new arginine toothpaste provided significantly greater reductions (p < 0.05) in dentin hypersensitivity in response to tactile (38.9%, 28.8%, and 11.6%) and air blast (16.8%, 26.4%, and 33.8%) stimuli than the benchmark commercial desensitizing toothpaste containing 2% potassium ion and 1450 ppm fluoride as NaF in a silica base, after two weeks, four weeks, and eight weeks of product use, respectively. "

Therapies and Procedures

1.	Solid-State Lasers 03/01/2004 - "Nd: YAG laser is safe and highly effective in treating dentine hypersensitivity." 10/01/2014 - "CO2 and Er:YAG laser are effective in treating dentin hypersensitivity and reducing its symptoms. " 06/01/2002 - "Promising results using Nd:YAG laser against dentin hypersensitivity have been reported. " 05/01/2014 - "Clinical and scanning electron microscopy evaluation of the Er,Cr:YSGG laser therapy for treating dentine hypersensitivity: short-term, randomised, controlled study." 03/01/2013 - "Comparative evaluation of the effects of Nd:YAG laser and a desensitizer agent on the treatment of dentin hypersensitivity: a clinical study."
2.	Lasers (Laser) 01/01/2015 - "The n-CAP and the laser were effective in reducing dentin hypersensitivity. " 01/01/2003 - "We concluded that the laser irradiation was effective in the treatment of cervical dentin hypersensitivity after 6 months." 12/01/2004 - "The purpose of this in vitro study was to verify the efficacy of Nd:YAG pulsed laser at 1064 nm in sealing dentinal tubules in vitro, with its resulting morphological changes using clinical parameters applicable to the treatment of dentin hypersensitivity. " 06/01/2013 - "This systematic review and meta-analysis assessed the efficacy of lasers in reducing dentin hypersensitivity (DH) as compared with placebo or no treatment. " 02/01/2015 - "The aim of this randomized, longitudinal clinical study was to evaluate different protocols for dentin hypersensitivity treatment with low-power laser at different dosages, desensitizing agent, and associations, for a period of 6 months. "
3.	Semiconductor Lasers 01/01/2014 - "The study concluded that application of diode laser (810 nm) was effective for the reduction of dentine hypersensitivity." 08/01/2009 - "Immediate efficacy of diode laser application in the treatment of dentine hypersensitivity in periodontal maintenance patients: a randomized clinical trial." 06/01/2008 - "To compare the clinical efficacy of the GaAlAs laser and dentin bonding agent in treating dentin hypersensitivity. " 01/01/2014 - "The aim of this study was to evaluate the use of diode laser (810 nm) in the treatment of cervical dentine hypersensitivity. " 01/01/2013 - "In Vitro Study of Dentin Hypersensitivity Treated by 980-nm Diode Laser."
4.	Dental Scaling 06/01/2004 - "Subgingival scaling and root-planing can induce the occurrence of root dentin hypersensitivity,therefore, desensitization treatment should be considered as a part of periodontal treatment plan." 12/01/1992 - "Patients were excluded if the dentin hypersensitivity could have been caused by cervical abrasion/erosion lesions deeper than 1 mm, cracked-tooth syndrome, caries lesions, operative caries treatment, and/or periodontal surgery or root scaling within the last 6 months. " 03/01/2009 - "To determine the efficacy of an in-office desensitizing paste containing 8% arginine and calcium carbonate relative to that of a commercially-available pumice prophylaxis paste in reducing dentin hypersensitivity instantly after a single application following a dental scaling procedure and to establish the duration of sensitivity relief over a period of 4 weeks and 12 weeks. " 02/01/2015 - "To determine the efficacy in reducing dentin hypersensitivity (DHS) of a combined in-office and home-use desensitizing system, each product containing 8% arginine and calcium carbonate (Test), following a dental scaling procedure, compared to the combination of a conventional prophylactic paste and a potassium nitrate dentifrice (Control), in a group of patients with known dentin hypersensitivity. " 04/01/2013 - "The aim of this single-site, randomized, controlled, double-blind, 3-arm parallel study was to determine the effectiveness of a prophylaxis paste containing 15% calcium sodium phosphosilicate (CSPS; NovaMin(®) ) with and without fluoride in reducing dentine hypersensitivity immediately after a single application and 28 days following dental scaling and root planing. "
5.	Oral Hygiene (Dental Hygiene) 03/01/2013 - "Dentin hypersensitivity (DHS) is a problematic clinical entity that may become an increasing clinical problem for dentists to treat as a consequence of patients retaining their teeth throughout life and improved oral hygiene practices. " 09/01/2003 - "The aim of this study was to establish the prevalence of dentine hypersensitivity and to examine some associated aetiological factors in a cross-sectional study of patients visiting the Periodontology and Oral Hygiene Clinic at Prince Phillip Dental Hospital, Hong Kong over a three-week period. " 03/01/2013 - "Correct diagnosis of dentin hypersensitivity including a patient's history screening and a brief clinical examination in combination with the identification of etiologic and predisposing factors, particularly dietary and oral hygiene habits associated with erosion and abrasion, is essential. " 01/01/1991 - "Traumatic oral hygiene procedures, excessive use of acid containing dietary fluids and certain dental treatments have been implicated in the occurrence of dentine hypersensitivity. " 07/01/2014 - "Gingival recessions may occur without any symptoms but may give rise to the patient concern about poor esthetics, dentine hypersensitivity, inability to perform oral hygiene procedures, and loss of the tooth. "