Dental Enamel Hypoplasia

An acquired or hereditary condition due to deficiency in the formation of tooth enamel (AMELOGENESIS). It is usually characterized by defective, thin, or malformed DENTAL ENAMEL. Risk factors for enamel hypoplasia include gene mutations, nutritional deficiencies, diseases, and environmental factors.
Also Known As:
Enamel Agenesis; Enamel Hypoplasia, Dental; Hypoplasia, Dental Enamel; Hypoplastic Enamel; Molar Incisor Hypomineralization; Ageneses, Enamel; Agenesis, Enamel; Enamel Ageneses; Enamel Hypoplasias; Enamel, Hypoplastic; Hypomineralization, Molar Incisor; Hypoplasia, Enamel; Hypoplasias, Enamel; Enamel Hypoplasia
Networked: 162 relevant articles (1 outcomes, 11 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Dental Caries (White Spot)
2. Cleft Lip (Harelip)
3. Abscess
4. Tooth Wear
5. X-Linked Dominant Hypophosphatemic Rickets (X-Linked Hypophosphatemia)


1. Brogårdh-Roth, Susanne: 3 articles (01/2015 - 01/2010)
2. Kim, J-W: 3 articles (04/2008 - 05/2004)
3. Matsson, Lars: 2 articles (01/2015 - 02/2011)
4. Masumo, Ray: 2 articles (05/2014 - 01/2012)
5. Billings, Ronald J: 2 articles (05/2014 - 04/2004)
6. Simmer, James P: 2 articles (01/2013 - 12/2002)
7. Phipps, Kathy R: 2 articles (09/2012 - 06/2010)
8. Griffin, R C: 2 articles (12/2009 - 01/2007)
9. Donlon, D: 2 articles (12/2009 - 01/2007)
10. Seow, W Kim: 2 articles (09/2009 - 01/2006)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Dental Enamel Hypoplasia:
1. CalciumIBA
2. FluoridesIBA
3. IronIBA
4. Vitamin DFDA LinkGeneric
5. Doxycycline (Vibramycin)FDA LinkGeneric
6. Dimenhydrinate (DMH)FDA LinkGeneric
7. Carbon MonoxideIBA
8. N 30IBA
9. TaurodontismIBA
10. Tetracycline (Achromycin)FDA LinkGeneric

Therapies and Procedures

1. Solid-State Lasers
2. Oral Hygiene (Dental Hygiene)
3. Parathyroidectomy
4. General Anesthesia
5. Crowns (Crown, Dental)
07/01/2014 - "MIM anomalies of the permanent first molars and deciduous second molars may include normal crowns with a constricted cervical region and thin, narrow, and short roots, whereas the affected maxillary central incisors may exhibit a hypoplastic enamel notch near the cervical third of the clinical crown. "
01/01/1995 - "The patient presented at the age of 8 years, and, following clinical and radiographic examination, a diagnosis was made of crown dilaceration with lingual displacement of the incisal third of the permanent mandibular central incisors, and hypoplastic enamel on all but the gingival third of their crowns. "
01/01/1997 - "Such preconditions may apply in the case of mandibulo-alveolar protrusion, anomalies where there is little or no option to fixing orthodontic appliances (enamel hypoplasia or shortened crowns), severe transversal discrepancies and skeletal dysgnathia with pronounced malpositioning in the alveolar process and the teeth. "
09/01/1999 - "This paper discusses the management of a patient with enamel hypoplasia using a combination of adhesive systems including enamel- and dentine-bonded veneers, dentine-bonded crowns, a cantilever resin-retained bridge, bonded amalgam restorations and chairside tin plating. "
04/01/2013 - "We show that tephra caused severe dental fluorosis, with bone fluoride levels up to 5,175 ppm. Among subadults, tephra caused pathologic development of newly emerging teeth typical of fluorosis, including enamel hypoplasia, breakages, pitting, mottling, and extremely rapid ablation of entire crowns down to underlying pulp cavities. "