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DEET (DET)

A compound used as a topical insect repellent that may cause irritation to eyes and mucous membranes, but not to the skin.

Also Known As:

DET; DETA; R 209; DEET, 2,5-di-Me-Analog; N,N-Diethyl-2,5-dimethylbenzamide; N,N-Diethyl-3-methylbenzamide; N,N-Diethyl-m-toluamide; N,N-Diethyltoluamide; R-209; N,N Diethyl 3 methylbenzamide; N,N Diethyl m toluamide; N,N Diethyltoluamide; R209; Benzamide, N,N-diethyl-3-methyl-

Networked: 264 relevant articles (29 outcomes, 42 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 58
- Amides: 231
  - Benzamides: 80
    - DEET: 264
- Carboxylic Acids: 83
  - Carbocyclic Acids
    - Benzoic Acids: 18
      - Benzamides: 80
        DEET: 264
        rebemide: 9
        Diethyltoluamide-20
        N,N-diethyl-3-hydroxymethylbenzamide
        N-ethyl-3-toluamide
        Pellit

Experts

1.	Picano, Eugenio: 8 articles (09/2008 - 04/2002)
2.	Xue, Rui-De: 7 articles (06/2014 - 11/2002)
3.	Sicari, Rosa: 6 articles (09/2008 - 02/2003)
4.	Ahn, Young-Joon: 5 articles (09/2015 - 07/2002)
5.	Qualls, Whitney A: 4 articles (06/2012 - 11/2011)
6.	Cortigiani, Lauro: 4 articles (09/2008 - 02/2003)
7.	Shyur, Lie-Fen: 3 articles (03/2013 - 02/2010)
8.	Nishiyama, Nobuhiro: 3 articles (06/2012 - 07/2009)
9.	Kataoka, Kazunori: 3 articles (06/2012 - 07/2009)
10.	Bowers, Doria F: 3 articles (06/2012 - 11/2011)

Related Diseases

1.	Bites and Stings (Sting) 09/01/2009 - "However, DEET-impregnated fabric strips at a concentration of 1.5 mg/cm(2) provided 4 h complete protection against mosquito bites and the reduction of man-landing rate varied between 51.21 and 100%. " 09/01/2009 - "The DEET-impregnated anklets, wristbands, shoulder and pocket fabric strips at a concentration of 2 mg/cm(2) provided 5 h complete protection against mosquitoes bites and the reduction of man-landing rate varied between 65.85 and 100%. " 02/01/2009 - "Thus, it can be concluded that while G10 and Insect Block 28 exhibited similarly powerful repellent activities with complete (100%) protection, 25% DEET was effective in minimizing bites with 99.68% protection. " 04/01/2011 - "There was no statistically significant differences in per cent protection against mosquito bites between Advanced Odomos and DEET cream (P>0.05) in respective doses. " 12/01/2010 - "This mosquito activation allowed the measurement of a significant reduction in the number of landings to bite on the warm body with increasing doses of deet (0.4 to 3.8 microg/cm2). "
2.	Malaria 03/01/2004 - "DEET mosquito repellent provides personal protection against malaria: a household randomized trial in an Afghan refugee camp in Pakistan." 01/01/2015 - "Repellent efficacy of DEET, MyggA, neem (Azedirachta indica) oil and chinaberry (Melia azedarach) oil against Anopheles arabiensis, the principal malaria vector in Ethiopia." 03/01/2008 - "DEET microencapsulation: a slow-release formulation enhancing the residual efficacy of bed nets against malaria vectors." 03/01/2004 - "DEET mosquito repellent sold through social marketing provides personal protection against malaria in an area of all-night mosquito biting and partial coverage of insecticide-treated nets: a case-control study of effectiveness." 01/01/2014 - "This study assessed whether 15% DEET topical repellent used in combination with LLINs can prevent greater malaria transmission than placebo and LLINs, in rural Tanzania. "
3.	Infection 06/01/1998 - "Radiolabeling and tracer studies confirmed that 7.5% DEET applied to the skin prior to infection was highly effective in preventing schistosomular migration to the lungs." 03/01/2004 - "DEET (diethyl-3-methylbenzamide), the widely used mosquito repellent, has the potential to prevent malarial infection but hitherto there has been no study demonstrating this possibility during normal everyday use. " 03/01/2012 - "Together, these results indicate that behavioral changes in mosquito host-seeking, blood feeding and sensitivity to DEET occurred in mosquitoes after SINV infection and dissemination." 03/01/2012 - "Ae. aegypti mosquitoes with a disseminated SINV infection fed an average of 4 h sooner than uninfected mosquitoes when offered a bloodmeal contained inside a DEET (N,N-diethyl-3-methylbenzamide) saturated (30%) bovine sausage casing. " 03/01/2012 - "Sindbis virus infection alters blood feeding responses and DEET repellency in Aedes aegypti (Diptera: Culicidae)."
4.	Neoplasms (Cancer) 01/01/2010 - "Optimism was significantly related to positive health practices (r = .209, p <.05) and cervical cancer screening knowledge (r = .224, p <.05) but not significantly related to previous cervical cancer screening behavior or screening frequency. " 05/01/2001 - "Transfection of FGF-BP into the SCCs Det 562 and FaDu did not promote tumor growth more than controls, and peri-tumoral microvessel density was lower in FGF-BP-transfected than in control tumors. " 11/01/1987 - "Of the DET patients, 100 constituted an ongoing surveillance group (354 colonoscopies) in which LGD was common, being seen on at least one occasion in 33% of patients (16.4% of examinations), but HGD was noted only once with a Dukes A cancer found at surgery. " 10/16/1969 - "[Det Norske Radiumhospitalet: the Tumor Center of Norway]." 01/01/2009 - "Systemic chemotherapies are associated with limited response rates and significant toxicity in patients with malignant digestive endocrine tumors (DET). "
5.	Body Weight (Weight, Body) 01/01/2011 - "Det treatment significantly attenuated food intake, body weight gain and fat mass gain relative to the Glar and Veh in high-fat fed animals, mirroring observations in humans. " 06/01/2008 - "No-observed-effect-levels (NOELs) of 200, 300, and 100mg/kg body weight (BW) were used as endpoints for DEET for acute, subchronic, and chronic exposures, respectively. " 01/01/1983 - "DEET, when applied dermally, did not alter sperm count, sperm morphology, sperm viability, body weight or food consumption at any dose level tested." 02/01/1996 - "A fourth experiment involved the determination of ADME patterns after dermal administration of [14C]DEET at a single low dose of 100 mg DEET/kg body weight. " 02/01/1996 - "Three experiments involved the determination of ADME patterns after oral administration of [14C]DEET as: 1) a single low dose (100 mg DEET/kg body weight); 2) a single high dose (500 mg DEET/kg body weight); and 3) a repeated low dose (100 mg DEET/kg body weight daily for 14 days). "

Related Drugs and Biologics

1.	Permethrin (Ambush)
2.	DEET (DET)
3.	Insect Repellents
4.	picaridin
5.	detomidine
6.	Ketamine
7.	polyethylene glycol-block-polyaspartic acid
8.	polyethylene glycol bis(succinimidyl succinate)
9.	zolazepam drug combination tiletamine
10.	ethyl- 3- (N- n- butyl- N- acetyl)aminopropionate

Related Therapies and Procedures

1.	Angioplasty (Angioplasty, Transluminal)
2.	Mosquito Nets
3.	Transplants (Transplant)
4.	Lasers (Laser)
5.	Renal Dialysis (Hemodialysis)