Cyclazocine

01/01/2000 - "Cyclazocine is a low-liability analgesic and potential therapeutic for the treatment of drug abuse. "

01/01/1974 - "A controlled study using cyclazocine in the treatment of narcotic addiction."
05/01/1968 - "Clinical studies of cyclazocine in the treatment of narcotic addiction."
09/01/1968 - "Basic concepts and use of cyclazocine in the treatment of narcotic addiction."
01/01/1967 - "Cyclazocine in the treatment of narcotic addiction."
06/01/1977 - "These results have important implications for drug abusers and for patients being treated for narcotic addiction with either a methadone maintenance program or a cyclazocine administration program."

05/01/1978 - "In order to characterize the discriminative stimulus properties of cyclazocine squirrel monkeys were trained to discriminate between intramuscular injections of 0.1 mg/kg of cyclazocine and drug vehicle in a discrete-trial avoidance paradigm in which a response on one of two levers would prevent or terminate the delivery of a mild electric shock to the tail. "
12/01/1979 - "The effects of morphine, pentazocine and cyclazocine were examined on a discrete-trial shock titration procedure. "
12/01/1979 - "At higher doses, morphine, pentazocine and cyclazocine increased median shock levels and decreased rates of responding in the absence of shock. "
12/01/1979 - "These effects were observed over a wider dose range with pentazocine and cyclazocine than with morphine; moreover, decreases in median shock level and increases in rates of responding in the absence of shock were of greater magnitude after pentazocine and cyclazocine than after morphine. "
12/01/1979 - "At a low dose, pentazocine, cyclazocine and morphine decreased median shock levels and increased rates of responding in the presence and in the absence of shock (i.e., during time out). "

04/01/1975 - "Duration studies in rodents were inconclusive, but in antagonism of morphine analgesia and miosis in the dog, oxilorphan was longer acting than naloxone and equivalent to dl-cyclazocine. "

10/01/1980 - "Cyclazocine in the treatment of opiate addiction: a review with recommendations."
11/01/1971 - "Cyclazocine treatment of opiate dependence: a progress report."
03/01/1970 - "A cyclazocine typology in opiate dependence."
05/01/1974 - "High-dose cyclazocine therapy of opiate dependence."
10/01/1980 - "The use of naloxone to alleviate side effects during cyclazocine induction and technological advances in implantable sustained-release devices may facilitate the effectiveness of cyclazocine treatment of opiate addiction. "