Cyanoacrylates

A group of compounds having the general formula CH2=C(CN)-COOR; it polymerizes on contact with moisture; used as tissue adhesive; higher homologs have hemostatic and antibacterial properties.

Also Known As:

Networked: 798 relevant articles (86 outcomes, 80 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Kreuter, Jörg: 5 articles (08/2011 - 02/2006)
2.	Rossi, Giuseppe: 4 articles (12/2014 - 02/2010)
3.	Rimondi, Eugenio: 4 articles (12/2014 - 02/2010)
4.	Ferrari, Angelo Paulo: 4 articles (06/2014 - 06/2007)
5.	Lin, Han-Chieh: 4 articles (10/2013 - 01/2008)
6.	Hou, Ming-Chih: 4 articles (10/2013 - 01/2008)
7.	Lee, Shou-Dong: 4 articles (10/2013 - 01/2008)
8.	Liao, Wei-Chih: 4 articles (10/2013 - 01/2008)
9.	Singer, Adam J: 4 articles (05/2010 - 05/2004)
10.	Matsumoto, Akio: 4 articles (08/2005 - 11/2002)

Related Diseases

1.	Hemorrhage 06/01/2011 - "Cyanoacrylate injection is more effective than beta-blocker therapy in preventing first gastric variceal bleeding." 09/01/2013 - "In patients with difficult-to-control GI bleeding failing conventional endoscopic therapies, cyanoacrylate spray was effective in achieving immediate hemostasis. " 02/01/2009 - "In conclusion, the endoscopic treatment with cyanoacrylate of actively bleeding GV, as well as the prophylaxis of the re-bleeding, is a safe and effective procedure and should be considered as a first-line therapy, whenever available." 01/01/1998 - "Sutureless pericardial patches fastened to the myocardium with cyanoacrylate glue to control hemorrhage under critical situations were easy to apply, safe and effective in this series of patients." 06/01/2011 - "We compared the efficacy of cyanoacrylate injection and beta-blockers in primary prophylaxis of gastric variceal bleeding. "
2.	Esophageal and Gastric Varices (Esophageal Varices) 12/07/2014 - "More trials are needed to clarify the efficacy of TIPS compared with other treatment modalities, including cyanoacrylate injection and balloon retrograde transvenous obliteration of gastric varices. " 01/01/2011 - "Cyanoacrylate injection (CI) might have a better outcome than VBL in the treatment of esophageal varices (EV) in these patients. " 06/01/2010 - "Endoscopic injection of gastric varices with cyanoacrylate is effective in prevention of rebleeding. " 09/01/2003 - "Cyanoacrylate treatment of gastric varices is safe, clinically effective, and cost effective." 03/07/2015 - "Endoscopic variceal obliteration using a small volume of aliquots with repeated cyanoacrylate injection was an effective and safe option for the treatment of gastric varices in children."
3.	Varicose Veins (Varicose Vein) 12/25/2007 - "PTVE with cyanoacrylate is safe and effective for the obliteration of gastroesophageal varices in cirrhotic patients." 11/01/1987 - "Cyanoacrylate is a very useful substance for obliterating large esophagogastric varices. " 12/01/2012 - "Definitive comparisons between TIPS, endoscopic cyanoacrylate, and BRTO will be challenging because the incidence of this type of varix is insufficient for large trials. " 10/01/2014 - "We conclude that cyanoacrylate injection effectively manages ectopic duodenal varices and can be used with a simple application technique." 10/01/2014 - "The varix was injected with 1cc of cyanoacrylate. "
4.	Wounds and Injuries (Trauma) 10/01/2014 - "Octyl-cyanoacrylate skin adhesive is effective for wound closure in posterior spinal surgery without increased risk of wound complications." 01/01/2015 - "Hence this study was undertaken to study the effect of long chain cyanoacrylate as an adhesive for intraoral wound closure and also to explore its hemostatic and antibacterial effects. " 12/01/2014 - "Influence of preoperative skin sealing with cyanoacrylate on microbial contamination of surgical wounds following trauma surgery: a prospective, blinded, controlled observational study." 12/01/2008 - "Prior studies have compared the wound bursting strengths (WBSs) of the cyanoacrylates immediately after wound closure. " 11/01/2004 - "A random study for management of wound by cyanoacrylate glue in 213 patients, irrespective of age and sex with different types of wounds was carried out over a period of 4 years (1996-2000). "
5.	Corneal Perforation 09/01/2006 - "Cyanoacrylate glue is an effective and safe method for sealing small corneal perforations. " 12/01/2013 - "Using cyanoacrylate glue for corneal perforations: caution with use of a needle and syringe." 05/01/2013 - "Double drape tectonic patch with cyanoacrylate glue in the management of corneal perforation with iris incarceration." 01/01/2013 - "Similar findings were noted in a 23-year man following cyanoacrylate glue application for corneal perforation. " 04/01/2012 - "Management of nontraumatic corneal perforation with tectonic drape patch and cyanoacrylate glue."

Related Drugs and Biologics

1.	Tissue Adhesives (Tissue Adhesive)
2.	ethanolamine oleate (Ethamolin)
3.	Fibrin Tissue Adhesive (Fibrin Sealant)
4.	Ethiodized Oil (Ethiodol)
5.	Polysorbates (PSML)
6.	Enbucrilate
7.	Adhesives (Glues)
8.	polidocanol (Laureth)
9.	Silicones
10.	Polymers

Related Therapies and Procedures

1.	Sclerotherapy
2.	Bandages (Bandage)
3.	Ligation
4.	Surgical Portasystemic Shunt (Portosystemic Shunt)
5.	Surgical Instruments (Clip)