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Cyanamide (Calcium Carbimide)

A cyanide compound which has been used as a fertilizer, defoliant and in many manufacturing processes. It often occurs as the calcium salt, sometimes also referred to as cyanamide. The citrated calcium salt is used in the treatment of alcoholism.

Also Known As:

Calcium Carbimide; Calcium Cyanamide; Colme; Temposil; Abstem; Carbimide; Cyanamide, Calcium (1:1) Salt; Cyanamide, Calcium (2:1) Salt; Cyanamide, Calcium Salt; Ipsen Brand of Calcium Carbimide; Calcium Cyanamide, Citrated; Calcium Salt Cyanamide; Carbimide, Calcium; Cyanamide, Calcium; Cyanamide, Citrated Calcium; Citrated Calcium Cyanamide

Networked: 118 relevant articles (5 outcomes, 9 trials/studies)

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Bio-Agent Context: Research Results

Experts

1.	Preedy, Victor R: 3 articles (07/2006 - 12/2003)
2.	Rubio, Sebastián: 2 articles (03/2014 - 05/2012)
3.	Pérez, Francisco J: 2 articles (03/2014 - 05/2012)
4.	Venkateswari, Jaganatha: 2 articles (11/2009 - 06/2008)
5.	Pang, Xuequn: 2 articles (11/2009 - 06/2008)
6.	Halaly, Tamar: 2 articles (11/2009 - 06/2008)
7.	Lavee, Shimon: 2 articles (11/2009 - 06/2008)
8.	Or, Etti: 2 articles (11/2009 - 06/2008)
9.	Foti, Caterina: 2 articles (01/2008 - 05/2003)
10.	Bonamonte, Domenico: 2 articles (01/2008 - 05/2003)

Related Diseases

1.	Alcoholism (Alcohol Abuse) 12/08/2012 - "Cyanamide has been used for decades for medical intentions in the treatment of alcoholism and for agricultural purposes as a plant growth regulator and bud-breaking agent. " 01/01/2008 - "Cyanamide is a chemical substance used in the treatment of chronic alcoholism as well in agriculture as a fertilizer. " 03/01/2005 - "A 46-year-old Japanese man is described in whom a generalized eruption developed about 1 month after taking cyanamide, a drug for alcoholism. " 09/01/1997 - "We administered cyanamide for alcoholism. " 11/01/1989 - "Calcium carbimide in alcoholism treatment. "
2.	Vitiligo 03/01/2013 - "Taken together, these studies not only identify cyanamide as a potential novel treatment for hyperpigmentary disorders, but also identify 9-cis retinoic acid as a pigment stimulatory agent that may have clinical utility in the treatment of hypopigmentary disorders, such as vitiligo."
3.	Body Weight (Weight, Body) 08/01/2002 - "Cyanamide was administered intraperitoneally (25 mg/kg body weight) to the cyanamide-treated group. " 01/01/1991 - "In male human volunteers a mean of 40% of oral administered cyanamide (mean dose 0.25 mg/kg body weight) was excreted via the urine as acetylcyanamide. " 01/01/1989 - "In addition to a delay in the increase of body weight as compared with the control group, the rats receiving cyanamide underwent a marked dispersion of the transaminase and LDH values. " 01/01/1989 - "Two experimental groups received cyanamide intraperitoneally, at a dose of 1 and 16 mg per kg of body weight, for 8 weeks. " 08/15/1986 - "Effects of cyanamide on body weight and brain monoamines and metabolites in rats."
4.	Dermatitis 09/01/1997 - "Cyanamide showed positive results in the drug lymphocyte stimulation test (198%) and the patch test led to the diagnosis of granulocytopenia and dermatitis induced by cyanamide. " 03/01/2014 - "Allergic dermatitis from cyanamide for chronic alcoholism detoxification." 09/01/1997 - "We report a 64-year-old male with granulocytopenia and dermatitis due to cyanamide treatment. " 10/04/2008 - "To identify the cause of the dermatitis, a patch test with calcium cyanamide and its breakdown products, cyanamide, urea and ammonium bicarbonate, was carried out on four cows. "
5.	Agranulocytosis (Granulocytopenia) 09/01/1997 - "To our knowledge, this is the first report of a case with granulocytopenia induced by cyanamide." 09/01/1997 - "Cyanamide-induced granulocytopenia." 09/01/1997 - "Cyanamide showed positive results in the drug lymphocyte stimulation test (198%) and the patch test led to the diagnosis of granulocytopenia and dermatitis induced by cyanamide. " 09/01/1997 - "We report a 64-year-old male with granulocytopenia and dermatitis due to cyanamide treatment. " 10/01/1990 - "[Agranulocytosis related to calcium cyanamide (Colme)]."

Related Drugs and Biologics

1.	Disulfiram (Antabuse)
2.	Tretinoin (Retinoic Acid)
3.	Alcohol Deterrents
4.	Ethanol (Ethyl Alcohol)
5.	Acetaldehyde
6.	Cyanamide (Calcium Carbimide)
7.	Aldehyde Dehydrogenase
8.	Messenger RNA (mRNA)
9.	Hydrogen
10.	Urea (Carbamide)

Related Therapies and Procedures

1.	Oral Administration
2.	Transplantation (Transplant Recipients)
3.	Intraperitoneal Injections
4.	Drug Therapy (Chemotherapy)
5.	Adrenalectomy