Cryptosporidiosis

02/01/2002 - "At the recommended levels, paromomycin reduced the oocyst output of birds by 67-82%, showing the highest efficacy of all drugs tested against avian cryptosporidiosis thus far. "
06/27/2000 - "The objective of this study was to evaluate the therapeutic efficacy of paromomycin against cryptosporidiosis in naturally infected lambs under field conditions. "
02/01/1993 - "Recent reports suggest that paromomycin may be useful in the treatment of intestinal cryptosporidiosis. "
11/16/2002 - "A prospective, controlled-blind field trial was conducted to evaluate the efficacy and safety of paromomycin sulphate, given for 10 days from birth, in preventing natural cryptosporidiosis in calves. "
08/01/1994 - "The present study aimed at investigating the efficiency of a recent antibiotic Aminosidine sulphate (Gabbroral) in experimental cryptosporidiosis. "

02/01/2004 - "Nitazoxanide is the first agent proven to be effective in cryptosporidiosis. "
01/01/2009 - "We hypothesised that a prolonged course of treatment with high dose nitazoxanide would be effective in treating cryptosporidiosis in HIV positive Zambian children. "
06/01/2012 - "Nitazoxanide was shown to be effective for cryptosporidiosis in the 1990s."
12/01/2004 - "Nitazoxanide is effective for cryptosporidiosis in immunocompetent and probably immunocompromised patients (with an alteration in the duration of treatment or the dosing regimen). "
08/01/1998 - "Nitazoxanide (NTZ), a drug currently being tested in human clinical trials for efficacy against chronic cryptosporidiosis, was assessed in cell culture and in two animal models. "

07/01/2005 - "The objective of this study was to evaluate the therapeutic efficacy of azithromycin treatment of cryptosporidiosis in naturally infected calves under field conditions. "
07/01/2002 - "To study the efficacy of short-term azithromycin in the management of cryptosporidiosis. "
07/01/2005 - "Efficacy of azithromycin dihydrate in treatment of cryptosporidiosis in naturally infected dairy calves."
07/01/2002 - "All 13 patients, who had symptoms of cryptosporidiosis, symptomatically improved with 5 days of treatment with azithromycin and became asymptomatic after 7 days of antibiotic, but stool sample was positive for cryptosporidium even after 7 days of therapy. "
07/01/2005 - "From the economic point view, authors suggest that the most effective dose of azithromycin for the treatment of cryptosporidiosis in calves should be at 1,500 mg/d for 7 days."

09/01/2010 - "Halofuginone lactate was shown to be effective in reducing clinical signs of cryptosporidiosis and environmental contamination. "
05/28/2014 - "The results demonstrated the efficacy of halofuginone lactate when given as a prophylactic treatment at 100 μg/kg BW during 10 days in reducing oocyst shedding, diarrhoea and mortality in goat kid cryptosporidiosis."
05/28/2014 - "Efficacy of halofuginone lactate against experimental cryptosporidiosis in goat neonates."
05/14/2011 - "To evaluate the efficacy of halofuginone lactate (Halocur; Intervet) when used prophylactically against cryptosporidiosis in dairy calves, 513 Holstein heifer calves were randomly distributed between two experimental groups. "
05/14/2011 - "Efficacy of halofuginone lactate in the prevention of cryptosporidiosis in dairy calves."

05/14/1999 - "Hyperimmune bovine colostrum specific for recombinant Cryptosporidium parvum antigen confers partial protection against cryptosporidiosis in immunosuppressed adult mice."
02/01/2015 - "The aim of the present study was to evaluate the antigen-detection capacity in the stool specimens using ELISA and oocyst detection by AP staining methods, for the diagnosis of human cryptosporidiosis. "
04/01/2011 - "This is the first report of the characterization of immune responses to cryptosporidiosis in Indian children and the first study to investigate human immune responses to the polymorphic gp40 antigen. "
11/22/2013 - "parvum EF-1α plays an essential role in mediating host cell entry by the parasite and, as such, could be a candidate vaccine antigen against cryptosporidiosis. "
10/01/2013 - "Antigen detection of Cryptosporidium spp by ELISA in stool can be a complementary tool in the diagnosis of cryptosporidiosis. "

05/17/2000 - "The results of our study suggest that decoquinate should have little efficacy for treatment of neonatal bovine cryptosporidiosis if administered once per day and that any clinical improvement observed in treated calves may be due to factors unrelated to decoquinate's effect on C. "
04/01/1997 - "Decoquinate reduced the severity of cryptosporidiosis in group B kids. "
09/15/2003 - "Daily treatment with decoquinate at the dosage used in this study did not affect oocyst shedding or clinical signs associated with cryptosporidiosis. "
04/01/1997 - "The purpose of this trial was to evaluate the effects of decoquinate at 2.5 mg/kg/day for 21 days to prevent an experimental cryptosporidiosis in kids. "
08/27/2005 - "Effect of different decoquinate treatments on cryptosporidiosis in naturally infected cashmere goat kids."

12/01/2007 - "Halofuginone treatment was effective in preventing and in reducing the death rate of cryptosporidiosis in these flocks."
12/01/2007 - "Halofuginone was effective in the treatment of diarrhoea caused by cryptosporidiosis (P < 0.01). "
12/01/2007 - "The first trial was designed to assess the efficacy of halofuginone in treating lamb diarrhoea caused by cryptosporidiosis, and in preventing the disease, using two schemes; halofuginone given for seven and for three consecutive days respectively. "
10/01/2009 - "To develop more precise estimates of the effects of halofuginone on calf cryptosporidiosis, meta-analyses were performed, including studies on prophylactic and therapeutic treatment. "
12/01/2007 - "The third trial was designed to examine the ability of halofuginone to reduce the death rate in flocks with cryptosporidiosis. "

09/01/1990 - "Immunotherapeutic efficacy of bovine colostral immunoglobulins from a hyperimmunized cow against cryptosporidiosis in neonatal mice."
09/01/1994 - "Kinetic and isotypic analysis of specific immunoglobulins from crew members with cryptosporidiosis on a U.S. "
01/01/1982 - "A case of fatal cryptosporidiosis in a child with primary immunoglobulin deficiency is described. "
01/01/1982 - "Chronic malabsorption due to cryptosporidiosis in a child with immunoglobulin deficiency."
03/01/1995 - "The aim of this study was to explore the intestinal immunoglobulin (Ig) secretions in patients with AIDS and their relationships to cryptosporidiosis. "

05/14/1999 - "parvum can be elicited in preparturient cows by direct injection of recombinant pCP15/60 plasmid DNA and that passive protection against cryptosporidiosis can be obtained by treating immunosuppressed mice with immune colostrum before and after C. "
06/01/2014 - "In Our findings, PCR -DNA showed that diagnosis cryptosporidiosis 2.1% was more sensitive than IFA. "
08/01/2013 - "To conclude, this one-step quantitative PCR is well suited to the routine diagnosis of cryptosporidiosis since practical conditions, including DNA extraction, quantification using well-defined standards, and identification of the two main species infecting humans, have been positively assessed. "
02/01/2012 - "Genomic DNA samples (n = 167) from faeces from humans with diarrhoea and diagnosed as cryptosporidiosis, and 100 uninfected control subjects, were tested for adenovirus 40/41, norovirus, Clostridium difficile, Campylobacter, Salmonella, Shigella, Cryptosporidium and Giardia by multiplexed-tandem PCR, and also characterized by single-strand conformation polymorphism analysis (SSCP) and selective sequencing. "
02/01/2009 - "meleagridis were detected in 97, 44 and 2, respectively, of the 143 Cryptosporidium oocyst DNA samples originating from Australians with clinical cryptosporidiosis. "

07/04/2000 - "In vitro and in vivo efficacy of lasalocid for treatment of experimental cryptosporidiosis."
01/01/1996 - "For cryptosporidiosis, which can not be cured by a conventional symptomatic treatment, only Lasalocid-Na is available. "
06/01/2005 - "Treatment procedure in the present study with Lasalocid-Na was found to be suitable in combination with an adequate infusion therapy for the treatment of calves on farms with problems related to cryptosporidiosis. "
10/11/2014 - "Administration of lasalocid-NA is preventive against cryptosporidiosis of newborn calves."
06/01/2005 - "[Cryptosporidiosis in newborn calves in Ankara region: clinical, haematological findings and treatment with Lasalocid-NA]."

03/01/2002 - "Because of reported efficacy of antibody-based immunotherapy, we studied the effect of inexpensive, commercially available oral bovine serum concentrate (BSC) in experimental cryptosporidiosis. "
01/01/1998 - "Passive antibody immunotherapy (PAI) for cryptosporidiosis is a treatment strategy that has been actively pursued in laboratory studies and early-stage clinical studies for the last decade. "
02/01/2012 - "No consistently effective parasite-specific pharmaceuticals or immunotherapies for control of cryptosporidiosis are presently available. "
11/01/2011 - "Cryptosporidiosis: host immune responses and the prospects for effective immunotherapies."
03/15/2000 - "No specific chemo- or immunotherapies exist to treat cryptosporidiosis and little molecular information is available to guide development of such therapies. "

03/01/2000 - "Since a fair number of cryptosporidiosis cases are still being reported in the New Orleans area after the introduction of highly active antiretroviral therapy, further studies are needed to provide insight into the existence of potential environmental sources of Cryptosporidium."
08/01/2014 - "Resolution of Cryptosporidiosis can be maintained with effective Highly Active Antiretroviral Therapy (HAART)."
01/01/2007 - "Cryptosporidiosis causes significant morbidity and mortality in human immunodeficiency virus (HIV)-infected patients who do not receive highly active antiretroviral therapy. "
12/01/2004 - "HIV-infected patients on highly active antiretroviral therapy have a dramatically lower incidence of cryptosporidiosis, attributable to the effects of intestinal immune reconstitution as well as the effect on the CD4 cell count. "
06/01/2004 - "[Highly Active AntiRetroviral Therapy and cryptosporidiosis]."

01/10/2011 - "Currently, drug therapy against cryptosporidiosis is limited making development of an effective vaccine attractive. "
07/01/2004 - "The slow development of anti-cryptosporidiosis chemotherapy is primarily due to the poor understanding on the basic metabolic pathways in this parasite. "
06/01/2004 - "In prospect, PIs could be valuable for the chemotherapy of cryptosporidiosis."
01/23/2004 - "Cryptosporidium parvum is a parasitic protozoan that causes the diarrheal disease cryptosporidiosis, for which no satisfactory chemotherapy is currently available. "
08/01/2003 - "This review focuses on chemotherapies used against the parasite, Cryptosporidium parvum, the causative agent of cryptosporidiosis. "

06/01/1993 - "The nodule became smaller in one patient when cholestasis improved after treatment for cryptosporidiosis. "
11/01/1989 - "Resolution of intestinal cryptosporidiosis after treatment of AIDS with AZT."
01/01/1996 - "We report two cases of cryptosporidiosis which were unusual because (i) extracellular invasive forms of the parasite were found in the bronchoalveolar lavage and (ii) the outcome was favorable in one patient after treatment with azithromycin."
04/01/1997 - "Resolution of AIDS associated cryptosporidiosis after treatment with indinavir."
04/01/1995 - "Maduramicin was also evaluated in a relapsing model of cryptosporidiosis in which the infection was observed to recur after treatments were discontinued. "

06/01/2005 - "Oral administration of hyperimmune anti-Cryptosporidium parvum ovine colostral whey confers a high level of protection against cryptosporidiosis in newborn NMRI mice."
04/01/1987 - "Oral administration of bovine colostrum anti-cryptosporidia antibody fails to alter the course of human cryptosporidiosis."