Creatine

05/01/2005 - "Although the results of this study demonstrated reduced fatigue rates in patients during high-intensity sprint intervals, further research is necessary in examining the efficacy of low-dose, short-term creatine supplementation."
06/01/1998 - "The results indicated that creatine supplementation in comparison with placebo treatment during rapid body mass reduction may help to maintain muscle PT and W(PT)1 at high angular velocities, not influencing Wmax and the rate of fatigue development during Wmax, but affecting adversely Ws max. "
01/01/1995 - "The fatigue resistance of creatine-depleted muscle was significantly improved, but tended to decrease by suspension and creatine supply, although it was still better than that in the control diet group. "
06/01/1997 - "Improved fatigue resistance not associated with maximum oxygen consumption in creatine-depleted rats."
01/01/2014 - "This study aimed to examine the effects of intermittent isometric fatigue on maximal voluntary contraction (MVC) strength, percent voluntary activation (%VA), peak twitch force (PTF), peak rate of force development (PRFD), half relaxation time (HRT), and maximal compound action potential (M-wave) amplitude of the soleus and medial gastrocnemius muscles before and after creatine (Cr) loading. "

09/01/2015 - "Creatine supplementation has been associated with increased cancer risk. "
06/01/2015 - "There were no statistically significant differences between benign and malignant tumors in the NAA-to-creatine and lipid-to-creatine ratios (p = 0.263 and 0.120, respectively). "
05/01/2013 - "A tendency for a significant positive correlation was found between normalized tumor creatine and Met uptake in the anaplastic tumors. "
12/01/2009 - "Higher perfusion and creatine within nonenhancing tumor in the presurgery MR were associated with subsequent tumor growth. "
12/01/2007 - "Tumors could not be discriminated when using metabolite ratios or ADC values alone, nor could they be differentiated using creatine (Cr) as an internal reference even in combination with ADC values. "

01/01/2003 - "Creatine has been shown to be effective in several animal models of neurodegenerative diseases and currently is being evaluated in early stage trials in PD. "
05/01/2011 - "Creatine, therefore, shows great promise in the treatment of a variety of neurodegenerative diseases."
05/01/2011 - "We carried out a number of studies of the neuroprotective effects of creatine in transgenic mouse models of neurodegenerative diseases. "
04/01/2015 - "There has been recent interest in creatine for its neuroprotective effects in neurodegenerative diseases and its potential as a therapeutic agent. "
01/01/2014 - "However, new uses for creatine have emerged suggesting that it may be important in preventing or delaying the onset of neurodegenerative diseases associated with aging. "

01/01/2013 - "However, using magnitude-based inference, supplementation with creatine post workout is possibly more beneficial in comparison to pre workout supplementation with regards to FFM, FM and 1-RM BP. The mean change in the PRE-SUPP and POST-SUPP groups for body weight (BW kg), FFM (kg), FM (kg) and 1-RM bench press (kg) were as follows, respectively: Mean ± SD; BW: 0.4 ± 2.2 vs. 0.8 ± 0.9; FFM: 0.9 ± 1.8 vs. 2.0 ± 1.2; FM: -0.1 ± 2.0 vs. -1.2 ± 1.6; Bench Press 1-RM: 6.6 ± 8.2 vs. 7.6 ± 6.1. Qualitative inference represents the likelihood that the true value will have the observed magnitude. "
06/01/2003 - "Significantly improved motor performance was present in both the 6- and 8-week treatment paradigms, while reduced body weight loss was only observed in creatine-supplemented R6/2 mice started at 6 weeks. "
06/15/2000 - "Body weight and motor performance on the rotarod test were significantly improved in creatine-supplemented R6/2 mice, whereas the onset of diabetes was markedly delayed. "
02/01/2014 - "Creatine supplementation significantly increased body weights of the athletes of endurance trial. "
06/01/2012 - "The purpose of this study was to examine the effects of 7 days of supplementation with 20 g·d⁻¹ of creatine monohydrate (CM) on mean power (MP) and peak power (PP) from the Wingate anaerobic test (WAnT), body weight (BW), 1-repetition maximum (1RM) bilateral leg extension (LE) strength, and 1RM bench press (BP) strength. "

05/01/2008 - "Protective effects of some creatine derivatives in brain tissue anoxia."
04/01/2008 - "Maternal creatine improved postnatal growth after birth hypoxia. "
02/14/2003 - "Addition of creatine, a compound that is known to afford protection against severe neuronal damage from longer periods of anoxia, prevented PS potentiation at a concentration of 10 mM, but not at a concentration of 1 mM. In addition, while 1 mM creatine by itself did not show any effect on PS amplitude of control slices, 10 mM creatine decreased PS amplitude also in such control slices, that had not been exposed to anoxia. "
10/27/2011 - "Using a model of intrapartum hypoxia in the precocial spiny mouse (Acomys cahirinus), the present study assessed the potential for maternal creatine supplementation during pregnancy to protect the developing brain from the effects of birth hypoxia. "
11/01/2010 - "This study demonstrates that creatine loading before birth significantly protects the diaphragm from hypoxia-induced damage at birth."